Abstract
While computer programs were purely tools for people to perform their creative activities 50 years ago, computer programs today, so called Artificial Intelligence(AI), can create intellectual products independently from people. The US has a leading role over all other countries in top-tier AI research, as well as most AI-related patent application filing. Does the US protect such inventions? If not, how does the US deal with liability concerning AI application? How does the development of AI call for intellectual property right law reforms in the US? The paper aims at addressing the above questions. Moreover, the paper provides a comprehensive analysis on AI-related patent in the US in comparison with the Vietnamese legal system. Descriptive legal research, analytical approach, comparison of legislation and case studies are employed in the paper.