Abstract
The aim of this study was to present the cases with family history of type 1 diabetes in a group of pediatric patients from the Clinic of Pediatrics, Constanta County Hospital, and to analyze the risk for relatives conferred by presence of particular DR genotypes. 8 out of 60 index cases had relatives affected with type 1 diabetes (13.33%). Of these, four had firstdegree relatives affected (6.67%) and were presented here. Although high-risk genotypes were more frequent in the group of familial cases, no association was found between DR genotype and family history of type 1 diabetes when statistical significance was tested (p value 0.119).