Abstract
Genital warts are one of the most common sexually transmitted infections caused by the human papilloma virus. Persons with genital warts may be infected by several types of human papilloma viruses: various types may have antagonistic or synergistic interactions, causing regression or recurrence of the existing lesions. No specific antiviral therapy is currently available. The treatment includes removal of symptomatic lesions on the skin and mucous surfaces. Apart from classical surgical procedures, local destruction of lesions is performed using various chemical and physical agents, whereas systemic therapy includes administration of agents promoting the immune system. The efficacy of treatment is not identical in all cases, and relapses are still inevitable. Combination therapy is often an alternative to monotherapy, while vaccine has an important role in prevention of genital warts.