Skip to main content
Have a personal or library account? Click to login
Determination of Zeranol and its Metabolites in Bovine Muscle Tissue with Gas Chromatography-Mass Spectrometry Cover

Determination of Zeranol and its Metabolites in Bovine Muscle Tissue with Gas Chromatography-Mass Spectrometry

Journal of Veterinary Research
Volume 56 (2012): Issue 3 (September 2012)
By: ,   and    
Open Access
|Jan 2013
References

References

  1. 1. ARO SOP 475B, Method validation using ResVal .Validation according to EC/2002/657, RIVM.
    Search in Google Scholar
  2. 2. Baldwin R.S., Williams R.D., Terry M.K.: Zeranol: a review of the metabolism, toxicology, and analytical methods for detection of tissue residues. Regul Toxicol Pharmacol 1983,, 9-25.
    Open DOISearch in Google Scholar
  3. 3. Blokland M.H., Sterk S.S., Stephany R.W., Launay F.M., Kennedy D.G., Van Ginkel L.A.: Determination of resorcylic acid lactones in biological samples by GC- MS. Discrimination between illegal use and contamination with fusarium toxins. Anal Bioanal Chem 2006,, 1221-1227.
    Open DOISearch in Google Scholar
  4. 4. Chichila T.M.P., Silvestre D., Covey T.R., Henion J.D.: Distribution of zeranol in bovine tissues determined by selected ion monitoring capillary gas chromatography/mass spectrometry. J Anal Toxicol 1988,, 310-318.
    Open DOISearch in Google Scholar
  5. 5. Daeseleire E., Vandeputte R., van Peteghem C.: Validation of multi-residue methods for the detection of anabolic steroids by GC-MS in muscle tissues and urine samples from cattle. Analyst 1998,, 2595-2598.
    Open DOISearch in Google Scholar
  6. 6. Erasmuson A.F., Scahill B.G., West D.M.: Natural zeranol (α-zearalanol) in the urine of pasture-fed animals. J Agr Food Chem 1994,, 2721-2725.
    Open DOISearch in Google Scholar
  7. 7. European Commission SANCO/2004/2726 Guidelines for the implementation of decision 2002/657/EC rev 4- December 2008.
    Search in Google Scholar
  8. 8. European Community Council Directive 96/22/EC of 29 April 1996 concerning the prohibition on the use in stockfarming of certain substances having a hormonal or thyreostatic action and of β-agonists, and repealing Directives 81/602/EEC, 88/146/EEC and 88/299/EEC. Off J Eur Commun L125:3.
    Search in Google Scholar
  9. 9. European Community Council Directive 96/23/EC of 29 April 1996 on measures to monitor certain substances and residues thereof in live animals and animal products and repealing Directives 85/358/EEC and 86/469/EEC and Decisions 89/187/EEC and 91/664/EEC. Off J Eur Commun L125:10.
    Search in Google Scholar
  10. 10. European Community Commission Decision No. 2002/657/EC of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretations of results. Off J Eur Commun L221:8.
    Search in Google Scholar
  11. 11. Fang X., Chen J., Gua D., Wang G.: Detection and identification of zeranol in chicken or rabbit liver by liquid chromatography-electrospray tandem mass spectrometry. J AOAC Int 2002,, 841-847.
    Open DOISearch in Google Scholar
  12. 12. ISO/11843: Capability of Detection (Part 1): Terms and Definitions (Part 2): Methodology in the Linear Calibration Case (2000).
    Search in Google Scholar
  13. 13. Jodlbauer J., Zöllner J., Lindner W.: Determination of zeranol, taleranol, zearalenone, α- and β-zearalenol in urine and tissue by high-performance liquid chromatography-tandem mass spectrometry. Chromatographia 2000,, 681-687.
    Open DOISearch in Google Scholar
  14. 14. Jonker M., Egmond H., Stephany R.W.: CRL-documents 389002096, pp. 39, December 1999.
    Search in Google Scholar
  15. 15. Kennedy D.G., Hewitt S.A., McEvoy J.D.G., Curie J.W., Cannavan A., Blanchflower W.J., Elliot C.T.: Zearalenon is formed fromspp. toxins in cattle. Food Addit Contam 1998,, 393-400.
    Open DOISearch in Google Scholar
  16. 16. Launay F.M., Young P.B., Sterk S.S., Blokland M.H., Kennedy D.G.: Confirmatory assay for zeranol, taleranol and thespp. toxins in bovine urine using liquid chromatography-tandem mass spectrometry Food Addit Contam 2004,, 52-62.
    Open DOISearch in Google Scholar
  17. 17. McCollum F.T.: Implanting beef calves and stocker cattle. Agricultural Communications 1998, L-2291, No. 4, The Texas A&M University System.
    Search in Google Scholar
  18. 18. Migdalof B.H., Dugger H.A., Heider J.G., Coombs R.A., Terry M.K.: Biotransformation of zeranol: disposition and metabolism in the female rat, rabbit, dog, monkey and man. Xenobiotica 1983,, 209-221.
    Open DOISearch in Google Scholar
  19. 19. Miles Ch.O., Erasmuson A.F., Wilkins A.L., Towers N.R., Smith B.L., Garthwaite I., Scahill B.G., Hansen R.P.: Ovine metabolism of zearalenone to -zearalanol (zeranol). J Agr Food Chem 1996,, 3244-3250.
    Open DOISearch in Google Scholar
  20. 20. Quintana J.B., Carpinteiro J., Rodríguez I., Lorenzo R.A., Carro A.M., Cela R.: Determination of natural and synthetic estrogens in water by gas chromatography with mass spectrometric detection. J Chromatogr A 2004,, 177-185.
    Open DOISearch in Google Scholar
  21. 21. Stolker A.A.M., Brinkman U.A.Th.: Analytical strategies for residue analysis of veterinary drugs and growth-promoting agents in food-producing animals-a review. J Chromatogr A 2005,, 15-53.
    Open DOISearch in Google Scholar
  22. 22. Van Bennekom E.O., Brouwer L., Laurant E.H.M., Hooijering H., Nielen M.W.F.: Confirmatory analysis method for zeranol, its metabolites and related mycotoxin in urine by liquid chromatography-negative ion electrospray tandem mass spectrometry. Anal Chim Acta 2002,, 151-160.
    Open DOISearch in Google Scholar
  23. 23. Vermeire D.A.: Implanting Cattle II: Implant Choices. Baby Doll Nutrition News, 1997, No. 4.
    Search in Google Scholar
  24. 24. Wolthers B.G., Kraan G.P.B.: Clinical aplications of gas chromatography and gas chromatography-mass spectrometry of steroids. J Chromatogr A 1999,, 247-274.
    Open DOISearch in Google Scholar
  25. 25. Woźniak B., Wojtoń B.: Detection of anabolic hormone residues in the urine and muscles of food-producing animals by HPTLC with application of extraction into a solid phase. Bull Vet Inst Pulawy 1996,, 55-59.
    Search in Google Scholar
  26. 26. Zöllner P., Jodlbauer J., Kleinova M., Kahlbacher H., Kuhn T., Hochsteiner W., Lindner W.: Concentration levels of zearalenone and its metabolites in urine, muscle tissue, and liver samples of pigs fed with mycotoxincontaminated oats. J Agr Food Chem 2002,, 2494-2501.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/v10213-012-0059-4 | Journal eISSN: 2450-8608 (formerly 2300-3235)
Journal RSS Feed
Language: English
Page range: 335 - 342
Published on: Jan 17, 2013
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Keywords:
bovine muscle tissue,
zeranol,
GC-MS
Related subjects:
Life sciences,
Molecular biology,
Microbiology and virology,
Life sciences, other,
Medicine,
Veterinary medicine

© 2013 Iwona Matraszek-Żuchowska, Barbara Woźniak, Jan Żmudzki, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons License.

Volume 56 (2012): Issue 3 (September 2012)
Previous article
Next article