Morphology of Human Glioblastoma Model Cultured in Ovo

Maciej Szmidt; Kaja Urbańska; Marta Grodzik; Piotr Orłowski; Ewa Sawosz; Mateusz Wierzbicki; Paweł Sysa

doi:10.2478/v10213-012-0046-9

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Morphology of Human Glioblastoma Model Cultured in Ovo

Journal of Veterinary Research

Volume 56 (2012): Issue 2 (June 2012)

By: Maciej Szmidt, Kaja Urbańska, Marta Grodzik, Piotr Orłowski, Ewa Sawosz, Mateusz Wierzbicki and Paweł Sysa

Open Access

|Jan 2013

Abstract

The aim of this study was the morphological characterisation of glioblastoma multiforme tumour grown in ovo. Tumour cells (U-87 MG) were implanted on the chorioallantoic membrane of chicken egg. The structural features of cultured tumours resembled the spontaneous glioblastoma multiforme; however, the differences were also indicated. Our results confirm applicability of in ovo culture in tumour genesis studies. The described novel model may be profoundly helpful for the future research on molecular mechanisms of tumour growth inhibition.

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Articles in this issue

DOI: https://doi.org/10.2478/v10213-012-0046-9 | Journal eISSN: 2450-8608

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Language: English

Page range: 261 - 266

Published on: Jan 17, 2013

Published by: National Veterinary Research Institute in Pulawy

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

glioblastoma multiforme,

U-87 MG,

in ovo model,

choriaoallantoic membrane.

Related subjects:

Life sciences,

Molecular biology,

Microbiology and virology,

Life sciences, other,

Medicine,

Veterinary medicine

© 2013 Maciej Szmidt, Kaja Urbańska, Marta Grodzik, Piotr Orłowski, Ewa Sawosz, Mateusz Wierzbicki, Paweł Sysa, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons License.

Volume 56 (2012): Issue 2 (June 2012)