Oxidative Damage to Proteins and Lipids During Ageing

S. Kuka; Z. Tatarkova; P. Kaplan

doi:10.2478/v10201-011-0027-3

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Oxidative Damage to Proteins and Lipids During Ageing

Acta Medica Martiniana

Volume 12 (2012): Issue 1 (March 2012)

By: S. Kuka, Z. Tatarkova and P. Kaplan

Open Access

|Sep 2012

Judge S, Leeuwenburgh C. Cardiac mitochondrial bioenergetics, oxidative stress, and aging. Am J Physiol Cell Physiol. 2007; 292(6): C1983-9210.1152/ajpcell.00285.200617344313
Open DOI Search in Google Scholar Open in PubMed
Harman D. Aging: a theory based on free radicals and radiation chemistry. J Gerontol. 1956; 2: 298-30010.1093/geronj/11.3.29813332224
Open DOI Search in Google Scholar Open in PubMed
Dufour E, Larsson NG. Understanding aging: revealing order out of chaos. Biochim Biophys Acta. 2004; 1658(1-2): 122-3210.1016/j.bbabio.2004.04.02015282183
Open DOI Search in Google Scholar Open in PubMed
Osiewacz HD. Role of mitochondria in ageing and age-related disease. Exp Gerontol. 2010; 45(7-8): 46510.1016/j.exger.2010.05.00120451599
Open DOI Search in Google Scholar Open in PubMed
Cocco T, Sgobbo P, Clemente M, Lopriore B, Grattagliano I, Di Paola M, Villani G. Tissue-specific changes of mitochondrials functions in aged rats: effect of a long- term dietary treatment with N-acetylcysteine. Free Radic Biol Med. 2005; 38(6): 796-80510.1016/j.freeradbiomed.2004.11.03415721990
Open DOI Search in Google Scholar Open in PubMed
Kaplán P. Kardiovaskulárne ochorenia a voľné radikály. P+M Turany, 2010; 120 s.
Search in Google Scholar
Stadtman ER. Protein oxidation and aging. Free Radical Research. 2006; 40(12): 1250-810.1080/1071576060091814217090414
Open DOI Search in Google Scholar Open in PubMed
Catalá A. Lipid peroxidation of membrane phospholipids generates hydroxy-alkenas and oxidized phospholipids active in physiological and/or pathological conditions. Chem Phys Lipids. 2009; 157(1): 1-1110.1016/j.chemphyslip.2008.09.00418977338
Open DOI Search in Google Scholar Open in PubMed
Halliwell B, Gutteridge JMC. Free radicals in biology and medicine: Antioxidant defences. 3rd ed. New York: Oxford Univ Press; 1999. Halliwell B, Gutteridge JMC eds.
Search in Google Scholar
Sivoňová M, Tatarková Z, Ďuračková Z, Dobrota D, Lehotský J, Matáková T, Kaplán P. Relationship between antioxidant potential and oxidative damage to lipids, proteins and DNA in aged rats. Physiol. Res. 2007; 56(6): 757-64
Search in Google Scholar
Ďuračková Z. Some current insights into oxidative stress. Physiol Res. 2010; 59(4): 459-6910.33549/physiolres.93184419929132
Open DOI Search in Google Scholar Open in PubMed
Harman D. The biologic clock: the mitochondria? J Am Geriatr Soc. 1972; 20(4): 145-710.1111/j.1532-5415.1972.tb00787.x5016631
Open DOI Search in Google Scholar Open in PubMed
Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial ROS-induced ROS release: an update and review. Biochim Biophys Acta. 2006; 1757(5-6): 509-1710.1016/j.bbabio.2006.04.02916829228
Open DOI Search in Google Scholar Open in PubMed
Romano AD, Serviddio G, de Matthaeis A, Bellanti F, Vendemiale G. Oxidative stress and aging. Nephrol. 2010; 23(Suppl. 15): S29-36
Search in Google Scholar
Gao L, Laude K, Cai H. Mitochondrial patophysiology, reactive oxygen species, and cardiovascular diseases. Vet Clin North Am Small Anim Pract. 2008; 38(1): 137-5510.1016/j.cvsm.2007.10.004270004118249246
Open DOI Search in Google Scholar Open in PubMed
Trifunovic A, Larsson NG. Mitochondrial disfunction as a cause of ageing. J Intern Med. 2008; 263(2):167-7810.1111/j.1365-2796.2007.01905.x18226094
Open DOI Search in Google Scholar Open in PubMed
Esterhazy D, King MS, Yakovlev G, Hirst J. Production of reactive oxygen species by complex I (NADH:ubiquinone oxidoreductase) from Escherichia coli and comparison to the enzyme from mitochondria. Biochemistry. 2008; 47(12): 3964-7110.1021/bi702243b18307315
Open DOI Search in Google Scholar Open in PubMed
Zhang HM, Zhang Y, Zhang BX. The role of mitochondrial complex III in melatonin-induced ROS production in cultured mesangial cells. J Pineal Res. 2011; 50(1): 78-82.10.1111/j.1600-079X.2010.00815.x300580920969621
Open DOI Search in Google Scholar Open in PubMed
Strkov AA, Fiskum G, Chinopoulos C, Lorenzo BJ, Browne SE, Patel MS, Beal MF. Mitochondrial alphaketoglutarate dehydrogenase complex generates reactive oxygen species. J Neurosci. 2004; 24(36): 7779-8810.1523/JNEUROSCI.1899-04.2004672993215356189
Open DOI Search in Google Scholar Open in PubMed
Wang W, Fang H, Groom L, Cheng A, Zhang W, Liu J, Wang X, Li K, Han P, Zheng M, Yin J, Mattson MP, Kao JP, Lakatta EG, Sheu SS, Ouyang K, Chen J, Dirksen RT, Cheng H. Superoxide flashes in single mitochondria. Cell. 2008; 134(2): 279-9010.1016/j.cell.2008.06.017254799618662543
Open DOI Search in Google Scholar Open in PubMed
Babušíková E, Jesenák M, Račay P, Dobrota D, Kaplán P. Oxidative alternations in rat heart homogenate and mitochondria during ageing. Gen Physiol Biophys. 2008; 27(2): 115-20
Search in Google Scholar
Kaplán P, Tatarková Z, Račay P, Lehotský J, Pavlíková M, Dobrota D. Oxidative modifications of cardiac mitochondria and inhibition of cytochrome c oxidase activity by 4-hydroxynonenal. Redox Rep. 2007; 12(5): 211-810.1179/135100007X20030817925093
Open DOI Search in Google Scholar Open in PubMed
Long J, Wang X, Gao H, Liu Z, Liu C, Miao M, Liu J. Malonaldehyde acts as a mitochondrial toxin: Inhibitory effects on respiratory function and enzyme activities in isolated rat liver mitochondria. Life Sci. 2006; 79(15): 1466-710.1016/j.lfs.2006.04.02416737718
Open DOI Search in Google Scholar Open in PubMed
Kumaran S, Subathra M, Balu M, Panneerselvam C. Age-associated decreased activities of mitochondrial electron transport chain complexes in heart and skeletal muscle: role of L-carnitine. Chem Biol Interact. 2004; 148(1-2): 11-810.1016/j.cbi.2003.10.01015223352
Open DOI Search in Google Scholar Open in PubMed
Tatarková Z, Kuka S, Račay P, Lehotský J, Dobrota D, Mištuna D, Kaplán P. Effects of aging on activities of mitochondrial electron transport chain complexes and oxidative damage in rat heart. Physiol Res. 2011; 60(2): 281-910.33549/physiolres.93201921114360
Open DOI Search in Google Scholar Open in PubMed
Davies SM, Poljak A, Duncan MW, Smythe GA, Murphy MP. Measurements of protein carbonyls, orthoand meta-tyrosine and oxidative phosphorylation complex activity in mitochondria from young and old rats. Free Radic Biol Med. 2001; 31(2): 181-9010.1016/S0891-5849(01)00576-7
Open DOI Search in Google Scholar
Preston CC, Oberlin AS, Holmuhamedov EL, Gupta A, Sagar S, Syed RH, Siddiqui SA, Raghavakaimal S, Terzic A, Jahangir A. Aging-induced alterations in gene transcripts and functional activity of mitochondrial oxidative phosphorylation complexes in the heart. Mech Ageing Dev. 2008; 129(6): 304-1210.1016/j.mad.2008.02.010246477418400259
Open DOI Search in Google Scholar Open in PubMed
Choksi KB, Papaconstantinou J. Age-related alterations in oxidatively damaged proteins of mouse heart mitochondrial electron transport chain complexes. Free Radic Biol Med. 2008; 44(10): 1795-80510.1016/j.freeradbiomed.2008.01.032242346818331850
Open DOI Search in Google Scholar Open in PubMed
Petrosillo G, Matera M, Moro N, Ruggerio FM, Paradies G. Mitochondrial complex I dysfunction in rat heart with aging: critical role of reactive oxygen species and cardiolipin. Free Radic Biol Med. 2009; 46(1): 88-9410.1016/j.freeradbiomed.2008.09.03118973802
Open DOI Search in Google Scholar Open in PubMed
Gómez LA, Monette JS, Chavez JD, Maier CS, Hagen TM. Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart. Arch Biochem Biophys. 2009; 490: 30-3510.1016/j.abb.2009.08.002276226819679098
Open DOI Search in Google Scholar Open in PubMed
Stadtman ER. Role of oxidant species in aging. Curr Med Chem. 2004; 11(9): 1105-1210.2174/092986704336534115134509
Open DOI Search in Google Scholar Open in PubMed
Lee S, Park Y, Zuidema MY, Hannink M, Zhang C. Effects of interventions on oxidative stress and inflammation of cardiovascular diseases. World J Cardiol. 2011; 3(1): 18-2410.4330/wjc.v3.i1.18303073321286214
Open DOI Search in Google Scholar Open in PubMed
Singh M, Nam DT, Arsenault M, Ramassamy C. Role of by-products of lipid oxidation in Alzheimer's disease brain: a focus on acrolein. J Alzheimers Dis. 2010; 21(3): 741-5610.3233/JAD-2010-10040520634576
Open DOI Search in Google Scholar Open in PubMed
Fernández-Checa JC, Fernández A, Morales A, Marí M, García-Ruiz C, Colell A. Oxidative stress and altered mitochondrial function in neurodegenerative diseases: lessons from mouse models. CNS Neurol Disord Drug Targets. 2010; 9(4): 439-5410.2174/18715271079155611320522012
Open DOI Search in Google Scholar Open in PubMed
Palardó FV, Lloret A, Lebel M, d Ischia M, Cogger VC, Le Couteur DG, Gadaleta MN, Castello G, Pagano G. Mitochondrial dysfunction in some oxidative stress-related genetic diseases: Ataxia-Telangiectasia, Down Syndrome, Fanconi Anaemia and Werner Syndrome. Biogerontology. 2010; 11(4): 401-1910.1007/s10522-010-9269-420237955
Open DOI Search in Google Scholar Open in PubMed
Shoham A, Hadziahmetovic M, Dunaief JL, Mydlarski MB, Schipper HM. Oxidative stress in diseases of human cornea. Free Radic Biol Med. 2008; 45(8): 1047-5510.1016/j.freeradbiomed.2008.07.02118718524
Open DOI Search in Google Scholar Open in PubMed
Moustafa AH, Ali M, Mohamed TM, Abdou HI. Oxidative stress and thyroid hormones in patients with liver diseases. Eur J Intern Med. 2009; 20(7): 703-810.1016/j.ejim.2009.08.00319818291
Open DOI Search in Google Scholar Open in PubMed
Giustarini D, Dalle-Donne I, Tsikas D, Rossi R. Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers. Crit Rev Clin Lab Sci. 2009; 46(5-6): 241-8110.3109/1040836090314232619958214
Open DOI Search in Google Scholar Open in PubMed
Ciechanover A. The ubiquitin proteolytic system: from an idea to the patient bed. Proc Am Thorac Soc. 2006; 3(1): 21-3110.1513/pats.200510-106JH16493148
Open DOI Search in Google Scholar Open in PubMed
Farout L, Friguet B. Proteasome Function in Aging and Oxidative Stress: Implications in Protein Maintenance Failure. Antioxid Redox Signal. 2006; 8(1-2): 205-1610.1089/ars.2006.8.20516487054
Open DOI Search in Google Scholar Open in PubMed
Jung T, Bader N, Grune T. Lipofuscin: formation, distribution, and metabolic consequences. Ann N Y Acad Sci. 2007; 1119: 97-11110.1196/annals.1404.00818056959
Open DOI Search in Google Scholar Open in PubMed
Semba RD, Nicklett EJ, Ferrucci L. Does accumulation of advanced glycation end products contribute to the aging phenotype? J Gerontol A Biol Sci Med Sci. 2010; 65(9): 963-7510.1093/gerona/glq074292058220478906
Open DOI Search in Google Scholar Open in PubMed
Savitha S, Panneerselvam C. Mitochondrial membrane damage during aging process in rat heart: potential efficacy of L-carnitine and DL alpha lipoic acid. Mech. Ageing Dev. 2006; 27(4): 349-5510.1016/j.mad.2005.12.00416430943
Open DOI Search in Google Scholar Open in PubMed
Savitha S, Panneerselvam C. Mitigation of age-dependent oxidative damage to DNA in rat heart by carnitine and lipoic acid. Mech Ageing Dev. 2007; 128(2): 206-1210.1016/j.mad.2006.11.02917196633
Open DOI Search in Google Scholar Open in PubMed
Tamilselvan J, Jayaraman G, Sivarajan K, Panneerselvam C. Age-dependent upregulation of p53 and cytochrome c release and susceptibility to apoptosis in skeletal muscle fiber of aged rats: role of carnitine and lipoic acid. Free Radic Biol Med. 2007; 43(12): 1656-6910.1016/j.freeradbiomed.2007.08.02818037131
Open DOI Search in Google Scholar Open in PubMed
Sudheesh NP, Ajith TA, Janardhanan KK, Krishnan CV. Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats. Food Chem Toxicol. 2009; 47(8): 2124-810.1016/j.fct.2009.05.03219500641
Open DOI Search in Google Scholar Open in PubMed
Salmon AB, Richardson A, Pérez VI. Update on the oxidative stress theory of aging: Does oxidative stress play a role in aging or healthy aging? Free Radic Biol Med. 2010; 48(5): 642-5510.1016/j.freeradbiomed.2009.12.015281959520036736
Open DOI Search in Google Scholar Open in PubMed
Judge S, Jang YM, Smith A, Selman C, Phillips T, Speakman JR, Hagen T, Leeuwenburgh C. Exercise by lifelong voluntary wheel running reduces subsarcolemmal and interfibrillar mitochondrial hydrogen peroxide production in the rat heart. Am J Physiol Regul Integr Comp Physiol. 2005; 289(6): R1564-7210.1152/ajpregu.00396.200516051717
Open DOI Search in Google Scholar Open in PubMed
Navarro A, Gomez C, López-Cepero JM, Boveris A. Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer. Am J Physiol Regul Integr Comp Physiol. 2004; 286(3): R505-1110.1152/ajpregu.00208.200314615275
Open DOI Search in Google Scholar Open in PubMed
Ascensão A, Ferreira R, Magalhães J. Exercise-induced cardioprotection - biochemical, morphological and functional evidence in whole tissue and isolated mitochondria. Int J Cardiol. 2007; 117(1): 16-3010.1016/j.ijcard.2006.04.07616860886
Open DOI Search in Google Scholar Open in PubMed
Sinclair DA. Toward a theory of caloric restriction and longevity regulation. Mech Ageing Dev. 2005; 126: 987-100210.1016/j.mad.2005.03.01915893363
Open DOI Search in Google Scholar Open in PubMed
Li Y, Daniel M, Tollefsbol T. Epigenetic regulation of caloric restriction in aging. BMC Med. 2011; 9(1): 98 [Epub ahead of print]10.1186/1741-7015-9-98317517421867551
Open DOI Search in Google Scholar Open in PubMed
Wakeling LA, Ions LJ, Ford D. Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions? Age (Dordr). 2009; 31(4):327-4110.1007/s11357-009-9104-5281304719568959
Open DOI Search in Google Scholar Open in PubMed