Diagnosis and Management of Posttraumatic Pancreatits in Children

Zarembo, Edgars; Engelis, Arnis; Zviedre, Astra; Petersons, Aigars

doi:10.2478/v10163-012-0013-9

Abstract

Traumas take a significant place in the etiology of children’s acute pancreatitis. Diagnostics and treatment of posttraumatic pancreatitis (PTRP) are complex. Delayed diagnosis of pancreatitis is connected with heightened morbidity and mortality. There is a remarkable difference in the tactic of treatment between adults and children because of the anatomical physiological reasons. Special attention has to be paid to children under the age of two years. The article summarizes the literature review and the experts’ conclusions from various European countries. Children who have PTRP should be concentrated in the specialized centres. It is necessary to have international cooperation of multicenters to improve the diagnostics and treatment of children PTRP.

References

1. Ammori BJ. Role of the gut in the course of severe acute pancreatitis // Pancreas, 2003; 26: 122 - 9
Search in Google Scholar
2. Bai HX et al. What have we learned about acute pancreatitis in children? // J of Pediatr Gastroenter & Nutrition, 2011; 52 ( 3 ): 262 - 270 10.1097/MPG.0b013e3182061d75362641621336157
Search in Google Scholar
3. Berney T et.al. Influence of severe underlaying pathology and hypovolemic shock on the development of acute pancreatitis in children // J Pediatr Surg, 1996; 31: 1256 - 1261
Search in Google Scholar
4. Bradley EL 3rd. A clinically based classification system for acute pancreatitis. Summary of the international Symposium on Acute Pancreatitis, Atlanta, GA, September 11 trough 13, 1992 // Arch Surg, 1993; 128 : 586 - 590
Search in Google Scholar
5. Brenner D et al.Estimated risks of radiation-induced fatal cancer from pediatric CT // Am J Roentgenol, 2001; 176: 289 - 296
Search in Google Scholar
6. Brown C et al. The diagnostic and therapeutic role of endoscopic retrograde cholangiopancreatography in children // J Pediatr Gastroenterol Nutr, 1993; 17: 19 − 23 10.1097/00005176-199307000-000038350208
Search in Google Scholar
7. Chen CF et al. Acute pancreatitis in children: 10 - year experience in a medical center // Acta Paediatr Taiwan, 2006; 47: 192 - 196
Search in Google Scholar
8. Escobar J et al. Cross - talk between oxidative stress and proinflammatory cytokines in acute pancreatitis; a kay role for protein phosphatase // Curr Pharm Des, 2009; 15 ( 26 ): 3027 - 42 10.2174/13816120978905807519754377
Search in Google Scholar
9. Dambrauskas Z et al. Different profiles of cytokine expression during mild and severe acute pancreatitis// World J Gastroenterol, 2010; 16 (15): 1845 - 1853
Search in Google Scholar
10. Goh SK et al. Childhood acute pancreatitis in a children’s hospital // Singapore Med J, 2003: 44: 453 - 456
Search in Google Scholar
11. Haddock G et.al. Acute pancreatitis in children: a 15-year rewiew // J Pediatr Surg, 1994; 29: 719 - 722
Search in Google Scholar
12. Kandula L, Lowe ME. Etiology and outcome of acute pancreatitis in infants and toddlers // J Pediatr, 2008; 152: 106-110
Search in Google Scholar
13. Lahoti BK et al. Paediatric pancreatic problems: A five -year experience // Afr J Paediatr Surg, 2010; 7: 151 - 155 Available at: http://www.afrjpaedsurg.org/text.asp?2010/7/3/151/70414 Accessed April 8, 2012 10.4103/0189-6725.7041420859018
Search in Google Scholar
14. Makabe H et al. Interleukin-18 levels reflect the long-term prognosis of acute lung injury and acute respiratory distress syndrome // J of Anesthesia, 2012, DOI: 10, 1007 / s00540 - 012 - 1409 - 3
Search in Google Scholar
15. Matsuno W et al. Amylase and lipase measurements in paediatric patients with traumatic pancreatic injuries // Injury, 2009; 40 ( 1 ): 66 - 71 10.1016/j.injury.2008.10.00319135195
Search in Google Scholar
16. Morinville VD et al. Increasing incidence of acute pancreatitis at an American pediatric tertiary care center: is greater awareness among physicians responsible? // Pancreas, 2010; 39: 5 - 8
Search in Google Scholar
17. Nydegger A et al. Changing incidence of acute pancreatitis: 10 - year experience at the Royal Children’s Hospital, Melbourne // J Gastroenterol Hepatol, 2007; 22: 1313 - 1316
Search in Google Scholar
18. Nydegger A et al. Childhood pancreatitis // J Gastroenterol Hepatol, 2006; 21 : 499 - 509
Search in Google Scholar
19. Parakh A et al. Ertapenem // Kathmandu Univ Med J (KUMJ), 2009; 7 ( 28 ): 454 - 60 10.3126/kumj.v7i4.2774
Search in Google Scholar
20. Park A et al. A comparsion of presentation and management trends in acute pancreatitis between infants/ toddlers and older children // J Pediatr Gastroenterol Nutr, 2010; 51: 167 - 70
Search in Google Scholar
21. Park A et al. Changing referral trends of acute pancreatitis in children: a 12-year single-center analysis // J Pediatr Gastroeterol Nutr, 2009; 49: 316 - 322
Search in Google Scholar
22. Pavle G. et al. SIRS score on admission and initial concentration of IL-6 as severe acute pancreatitis outcome predictors // Hepatogastroenterology, Mar-Apr 2010; 57 ( 98 ): 349 - 53
Search in Google Scholar
23. Powell J, Miles R. Antibiotic prophylaxis in the initial management of acute severe pancreatitis // Br J Surg, 1998; 85 10.1046/j.1365-2168.1998.00767.x9635800
Search in Google Scholar
24. Rescorla R et al. The efficacy of early ERCP in pediatric pancreatic trauma // J Pediatr Surg, 1995; 30: 335 - 340
Search in Google Scholar
25. Sanchez-Ramirez CA et al. Acute and recurrent pancreatitis in children: etiological factors // Acta Paediatr, 2007; 96: 534 - 537
Search in Google Scholar
26. Smith D et al. Delayed diagnosis of pancreatic transection after blunt abdominal trauma // J Trauma, 1996; 40: 1009 - 1013
Search in Google Scholar
27. Stringer MD et al. Multidisciplinary management of surgical disorders of the pancreas in childhood // J Pediatr Gastroenterol Nutr, 2005; 40: 363 - 367
Search in Google Scholar
28. Tiao MM et al. Pancreatitis in children: clinical analysis of 61 cases in southern Taiwan // Chang Gung Med J, 2002; 25: 162 - 168
Search in Google Scholar
29. Werlin SL, et al. Pancreatitis in children // J Pediatr Gastroenterol Nutr 2003; 37: 591-595
Search in Google Scholar
30. Wittendorff H et al. Blunt isolated pancreatic trauma. Diagnostic problems - a clinical and radiological challenge // Available at: http://www.ncbi.nlm.nih.gov/pubmed/12051048 Accessed: April 30, 2012
Search in Google Scholar
31. Zhu HH, Jiang LL. Serum inter-cellular adhesion molecule 1 is an early marker of diagnosis and prediction of severe acute pancreatitis // World J Gastroenterol, 2012; 18 (20 ) : 2554 - 2560 Available at: http://www.wjgnet.com/1007-9327/full/v18/i20/2554.htm Accessed: May 28, 2012
Search in Google Scholar
32. Khokhar AS, Seidner DL. The pathophysiology of pancreatitis // Nutr Clin Pract, 2004; 19: 5 - 15
Search in Google Scholar
33. De Banto JR et al. Acute pancreatitis in children // Am J Gastroenterol, 2002; 97: 1726 - 31
Search in Google Scholar

Diagnosis and Management of Posttraumatic Pancreatits in Children

Abstract

Paradigm

My account