Skip to main content
Have a personal or library account? Click to login
Toxicological aspects of the use of phenolic compounds in disease prevention Cover

Toxicological aspects of the use of phenolic compounds in disease prevention

Interdisciplinary Toxicology
Volume 4 (2011): Issue 4 (December 2011)
By:   
Open Access
|Feb 2012
References

References

  1. Agte V and Tarwadi K. (2010). The importance of nutrition in the prevention of ocular disease with special reference to cataract.(3): 166-172.
    Search in Google Scholar
  2. Ahmad A, Asad SF, Singh S and Hadi SM. (2000). DNA breakage by resveratrol and Cu(II): reaction mechanism and bacteriophage inactivation.: 29-37.
    Search in Google Scholar
  3. Angelone T, Pasqua T, Di Majo D, Quintieri AM, Filice E, Amodio N, Tota B, Giammanco M and Cerra MC. (2010). Distinct signalling mechanisms are involved in the dissimilar myocardial and coronary effects elicited by quercetin and myricetin, two red wine flavonols.(5): 362-371.
    Search in Google Scholar
  4. Baraldo M. (2008). The influence of circadian rhytms on the kinetics of drugs in humans.(2): 175-192.
    Search in Google Scholar
  5. Barjesteh van Waalwijk van Doorn-Khosrovani S, Janssen J, Maas LM, Godschalk RW, Nijhuis JG and Schooten FJ. (2007). Dietary flavonoids induce MLL translocations in primary human CD34+ cells.: 1703-1709.
    Open DOISearch in Google Scholar
  6. Bhat KPL and Pezzuto JM. (2002). Cancer chemopreventive activity of resveratrol.: 210-229.
    Search in Google Scholar
  7. Birt DF, Hendrich S and Wang WQ. (2001). Dietary agents in cancer prevention: flavonoids and isoflavonoids.: 157-177.
    Search in Google Scholar
  8. Biswal SS, Datta K, Shaw SD, Feng X, Robertson JD and Kehrer JP. (2000). Glutathione oxidation and mitochondrial depolarization as mechanisms of nordihydroguaiaretic acid-induced apoptosis in lipoxygenase-deficient FL5.12 cells.: 77-83.
    Search in Google Scholar
  9. Brazier NC, Mitchell AH and Levine MD. (2003). Understanding drug-herb interaction.: 427-430.
    Search in Google Scholar
  10. Brown JP. (1980). A review of the genetic effects of naturally occurring flavonoids, anthraquinones and related compounds.: 243-277.
    Search in Google Scholar
  11. Byrd JC, Shinn C, Waselenko JK, Fuchs EJ, Lehman TA, Nguyen PL, Flinn IW, Diehl LF, Sausville E and Grever MR. (1998). Flavopiridol induces apoptosis in chronic lymphocytic leukemia cellsactivation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53.: 3804-3816.
    Search in Google Scholar
  12. Canivenc-Lavier MC, Bentejac M, Leclerc MH, Siess MH, Latruffe N and Suschetet M. (1996). Differential effects of nonhydroxylated flavonoids as inducers of cytochrome P450 1A and 2B isozymes in rat liver.: 348-353.
    Search in Google Scholar
  13. Chung LY, Cheung TC, Kong SK, Fung KP, Choy YM, Chan ZY and Kwok TT. (2001). Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells.: 1207-1214.
    Search in Google Scholar
  14. Colalto C. (2010). Herbal interactions on absorption of drugs: Mechanisms of action and clinical risk assessment.: 207-227.
    Search in Google Scholar
  15. Cos P, De Bruyne T, Apers S, Vanden Berghe D, Pieters L and Vlietinck AJ. (2003). Phytoestrogens: recent developments.: 589-599.
    Search in Google Scholar
  16. Crozier A, Del Rio D and Clifford MN. (2010). Bioavailability of dietary flavonoids and phenolic compounds.(6): 446-467.
    Search in Google Scholar
  17. Csokay B, Prajda N, Weber G and Olah E. (1997). Molecular mechanisms in the antiproliferative action of quercetin.: 2157-2163.
    Search in Google Scholar
  18. Cvorovic J, Tramer F, Granzotto M, Candussio L, Decorti G and Passamonti S. (2010). Oxidative stress-based cytotoxicity of delphinidin and cyanidin in colon cancer cells.: 151-157.
    Search in Google Scholar
  19. Decker EA. (1997). Phenolics: pro-oxidants or antioxidants?: 396-407.
    Open DOISearch in Google Scholar
  20. Degli Esposti M. (1998). Inhibitors of NADH-ubiquinone reductase: an over-view. Biochim Biophys Acta: 222-235.
    Search in Google Scholar
  21. Doostdar H, Burke MD and Mayer RT. (2000). Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1.: 31-38.
    Search in Google Scholar
  22. Duffy C, Perez K and Partridge A. (2007). Implications of phytoestrogen intake for breast cancer.: 260-277.
    Search in Google Scholar
  23. Dunnick JK and Hailey JR. (1992). Toxicity and carcinogenicity studies of quercetin, a natural component of foods.: 423-431.
    Search in Google Scholar
  24. Duthie GG, Gardner PT and Kyle JA. (2003). Plant polyphenols: are they the new magic bullet?: 599-603.
    Open DOISearch in Google Scholar
  25. EMEA Commitee on Herbal Medicinal Products. (2006). Guideline on the assessment of clinical safety and efficacy in the preparation of community herbal monographs for well-estabilished and of community herbal monographs/entries to the community list for traditional herbal medicinal products/substances/preparations. Avaible from:
    Search in Google Scholar
  26. Fang N and Casida JE. (1998). Anticancer action of cube insecticide: correlation for rotenoid constituents between inhibition of NADH: ubiquinone oxidoreductase and induced ornithine decarboxylase activities.: 3380-3384.
    Search in Google Scholar
  27. Feng R, Ni HM, Wang SY, Tourkova IL, Shurin MR, Harada H and Yin XM. (2007). Cyanidin-3-rutinoside, a natural polyphenol antioxidant, selectively kills leukemic cells by induction of oxidative stress.: 13468-13476.
    Search in Google Scholar
  28. Ferguson LR and Philpott M. (2008). Nutrition and mutagenesis.: 313-329.
    Search in Google Scholar
  29. Fischer PM and Lane DP. (2000). Inhibitors of cyclin-dependent kinases as anti-cancer therapeutics.: 1213-1245.
    Search in Google Scholar
  30. Formica JV and Regelson W. (1995). Review of the biology of quercetin and related bioflavonoids.: 1061-1080.
    Search in Google Scholar
  31. Fraga CG, Galleano M, Verstraeten SV and Oteiza PI. (2010). Basic biochemical mechanisms behind the health benefits of polyphenols.: 435-445.
    Search in Google Scholar
  32. Franconi F, Brunelleschi S, Steardo L and Cuomo V. (2007). Gender differences in drug responses.(2): 81-95.
    Search in Google Scholar
  33. Fuhr U. (1998). Drug interactions with grapefruit juice. Extent, probablemechanism and clinical relevance.(4): 251-272.
    Search in Google Scholar
  34. Furukawa A, Oikawa S, Murata M, Hiraku Y and Kawanishi S. (2003). (_)-Epigallocatechin gallate causes oxidative damage to isolated and cellular DNA.: 1769-1778.
    Search in Google Scholar
  35. Galati G and O'Brien PJ. (2004). Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties.(3): 287-303.
    Search in Google Scholar
  36. Galati G, Sabzevari O, Wilson JX and O'Brien PJ. (2002). Pro-oxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics.: 91-104.
    Search in Google Scholar
  37. Gerwirtz DA. (1991). Does bulk damage to DNA explain the cytostatic and cytotoxic effects of topoisomerase II inhibitors?: 2253-2258.
    Open DOISearch in Google Scholar
  38. Ghosh D and Konishi T. (2007). Anthocyanins and anthocyanin-rich extracts: role in diabetes and eye function.(2): 200-208.
    Search in Google Scholar
  39. Gill WB. (1988). Effects on human males of in utero exposure to exogenous sex hormones, in(Mori T and Nagasawa H eds) pp. 161-177, CRC, Boca Raton, FL.
    Search in Google Scholar
  40. Goldstein JC, Waterhouse P, Juin P, Evan GI and Green DR. (2000). The coordinate release of cytochrome c is rapid, complete, and kinetically invariant.: 156-162.
    Search in Google Scholar
  41. Guarrera S, Sacerdote C, Fiorini L, Marsala R, Polidoro S, Gamberini S, Saletta F, Malaveille C, Talaska G, Vineis P and Matullo G. (2007). Expression of DNA repair and metabolic genes in response to a flavonoid-rich diet.: 525-533.
    Search in Google Scholar
  42. Guengerich FP, Shimada T, Yun CH, Yamazaki H, Raney KD, Their R, Coles B and Harris TM. (1994). Interactions of ingested food, beverage, and tobacco components involving human cytochrome P4501A2, 2A6, 2E1, and 3A4 enzymes.: 49-53.
    Search in Google Scholar
  43. Hadi SM, Asad SF, Singh S and Ahmad A. (2000). Putative mechanism for anticancer and apoptosis-inducing properties of plantderived polyphenolic compounds.: 167-171.
    Search in Google Scholar
  44. Halliwell B. (2007). Dietary polyphenols: good, bad, or indifferent for your health?: 341-347.
    Open DOISearch in Google Scholar
  45. Halliwell B. (2008). Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture andstudies?(2): 107-112.
    Open DOISearch in Google Scholar
  46. Halliwell B. (2009). The wanderings of a free radical.: 531-542.
    Search in Google Scholar
  47. Hirose M, Fukushima S, Sakata T, Inui M and Ito N. (1983). Effect of quercetin on two-stage carcinogenesis of the rat urinary bladder.: 23-27.
    Search in Google Scholar
  48. Hodek P, Hanustiak P, Krizkova J, Mikelova R, Krizkova S, Stiborova M, Trnkova L, Horna A, Beklova M and Kizek R. (2006). Toxicological aspects of flavonoid interaction with biomacromolecules.(Suppl 2): 14-17.
    Search in Google Scholar
  49. Hodek P, Trefil P and Stiborova M. (2002). Flavonoids—potent and versatile biologically active compounds interacting with cytochromes P450.: 1-21.
    Search in Google Scholar
  50. Hou DX, Ose T, Lin S, Harazoro K, Imamura I, Kubo M, Uto T, Terahara N, Yoshimoto M and Fujii M. (2003). Anthocyanidins induce apoptosis in human promyelocytic leukemia cells: structure-activity relationship and mechanisms involved.: 705-712.
    Search in Google Scholar
  51. Huang YT, Hwang JJ, Lee PP, Ke FC, Huang JH, Huang CJ, Kandaswami C, Middleton EJr and Lee MT. (1999). Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor.: 999-1010.
    Search in Google Scholar
  52. Ibrahim AR and Abul-Hajj YJ. (1990). Aromatase inhibition by flavonoids.: 257-260.
    Search in Google Scholar
  53. Ito N, Hagiwara A, Tamano S, Kagawa M, Shibata MA, Kurata Y and Fukushima S. (1989). Lack of carcinogenicity of quercetin in F334/DuCrj rats.: 317-325.
    Search in Google Scholar
  54. Izzo AA and Ernst E. (2001). Interactions between herbal medicines and prescribed drugs: a systematic review.(15): 2163-2175.
    Search in Google Scholar
  55. Jaganatah IB and Crozier A. (2010). Dietary flavonoids and phenolic compounds, in Plant Phenolics and Human Health (Fraga CG ed), pp. 1-50, John Wiley & Sons Inc., Hoboken, NJ.
    Search in Google Scholar
  56. Jaganathan SK and Mandal M. (2009). Antiproliferative effects of honey and of its polyphenols: a review.: 830616.
    Search in Google Scholar
  57. Kalt W, Hanneken A, Milbury P and Tremblay F. (2010). Recent research on polyphenolics in vision and eye health.: 4001-4007.
    Search in Google Scholar
  58. Katdare M, Jinno H, Osborne MP and Telang NT. (1999). Negative growth regulation of oncogene-transformed human breast epithelial cells by phytochemicals: role of apoptosis.: 247-252.
    Search in Google Scholar
  59. Kellis JT and Vickery LE. (1984). Inhibition of human estrogen synthetase (aromatase) by flavones.: 1032-1034.
    Search in Google Scholar
  60. Kim JS, He L and Lemasters JJ. (2003). Mitochondrial permeability transition: a common pathway to necrosis and apoptosis.: 463-470.
    Search in Google Scholar
  61. Klejdus B, Mikelova R, Petrlova J, Potesil D, Adam V, Stiborova M, Hodek P, Vacek J, Kizek R and Kuban V. (2005). Evaluation of isoflavone aglycon and glycoside distribution in soy plants and soybeans by fast column high-performance liquid chromatography coupled with a diode-array detector.: 5848-5852.
    Search in Google Scholar
  62. Knekt P, Kumpulainen J, Järvinen R, Rissanen H, Heliövaara M, Reunanen A, Hakulinen T and Aromaa A. (2002). Flavonoid intake and risk of chronic diseases.(3): 560-568.
    Search in Google Scholar
  63. Kohn MC, Walker NJ, Kim AH and Portier CJ. (2001). Physiological modeling of a proposed mechanism of enzyme induction by TCD.: 193-208.
    Search in Google Scholar
  64. Kong AN, Yu R, Chen C, Mandlekar S and Primiano T. (2000). Signal transduction events elicited by natural products: role of MAPK and caspase pathways in homeostatic response and induction of apoptosis.(1): 1-16.
    Search in Google Scholar
  65. Kroemer G. (2003). Mitochondrial control of apoptosis: an introduction.: 433-435.
    Search in Google Scholar
  66. Kuo SM. (1996). Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells.: 41-48.
    Search in Google Scholar
  67. Lockwood B. (2008). The beneficial effects of soy isoflavones in osteoporosis of the elderly.(5): 38-41.
    Search in Google Scholar
  68. Makela S, Poutanen M, Kostian ML, Lehtimaki N Strauss L, Santti R and Vihko R. (1998). Inhibition of 17beta-hydroxysteroid oxidoreductase by flavonoids in breast and prostate cancer cells.(3): 310-316.
    Search in Google Scholar
  69. Messina M and Wood CE. (2008). Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary.(1): 17-28.
    Search in Google Scholar
  70. Messina M, McCaskill-Stevens W and Lampe JW. (2006). Addressing the soy and breast cancer relatioship: review, commentary, and workshop proceedings.(18): 1275-1284.
    Search in Google Scholar
  71. Metodiewa D, Jaiswal AK, Cenas N, Dickancaite E and Segura-Aguilar J. (1999). Quercetin may act as a cytotoxic pro-oxidant after its metabolic activation to semiquinone and quinoidal product.(1-2): 107-116.
    Search in Google Scholar
  72. Miadokova E. (2009). Isoflavonoids - an overview of their biological activities and potential health benefits.(4): 211-218.
    Search in Google Scholar
  73. Middleton E and Kandaswami C. (1994). The impact of plant flavonoids on mammalian biology: implications for immunity, inflammation and cancer, in(Harborne JB ed) pp. 619-652, Chapman & Hall, London.
    Search in Google Scholar
  74. Miksicek RJ. (1995). Estrogenic flavonoids: structural requirements for biological activity.: 44-50.
    Search in Google Scholar
  75. Miniello VL, Moro GE, Tarantino M, Natile M, Granieri L and Armenio L. (2003). Soy-based formulas and phyto-oestrogens: a safety profile.: 93-100.
    Search in Google Scholar
  76. Morino K, Matsukura N, Kawachi T, Ohgaki H, Sugimura T and Hirono I. (1982). Carcinogenicity test of quercetin and rutin in golden hamsters by oral administration.: 93-97.
    Search in Google Scholar
  77. Newbold RR, Banks EP, Bullock B and Jefferson WN. (2001). Uterine adenocarcinoma in mice treated neonatally with genistein.(11): 4325-4328.
    Search in Google Scholar
  78. Ni H, Simile C, and Hardy AM. (2002). Utilization of complementary and alternative medicine by United States adults: results from the 1999 national health interview survey.: 353-358.
    Search in Google Scholar
  79. Omiecinski CJ, Remmel RP and Hosagrahara VP. (1999). Concise review of the cytochrome P450s and their roles in toxicology.: 151-156.
    Search in Google Scholar
  80. Oyama Y, Noguchi S, Nakata M, Okada Y, Yamazaki Y, Funai M, Chikahisa L and Kanemaru K. (1999). Exposure of rat thymocytes to hydrogen peroxide increases annexin V binding to membranes: inhibitory actions of deferoxamine and quercetin.: 47-52.
    Search in Google Scholar
  81. Pamukcu AM, Yalciner S, Hatcher JF and Bryan GT. (1980). Quercetin, a rat intestinal and bladder carcinogen present in bracken fern (: 3468-3472.
    Search in Google Scholar
  82. Panes J, Gerritsen ME, Anderson DC, Miyasaka M and Granger DN. (1996). Apigenin inhibits tumor necrosis factor-induced intercellular adhesion molecule-1 upregulation: 279-286.
    Search in Google Scholar
  83. Paschka AG, Butler R and Young CY. (1998). Induction of apoptosis in prostate cancer cell lines by the green tea component, (_)-epigallocatechin-3-gallate.(1-2): 1-7.
    Search in Google Scholar
  84. Patil BS, Jayaprakasha GK, Chidambara Murthy KN and Vikram A. (2009). Bioactive compounds: historical perspectives, opportunities, and challenges.(18): 8142-8160.
    Search in Google Scholar
  85. Rahman A, Shahabuddin A, Hadi SM and Parish JH. (1990). Complexes involving quercetin, DNA and Cu(II).(11): 2001-2003.
    Search in Google Scholar
  86. Rhone M and Basu A. (2008). Phytochemicals and age-related eye diseases.(8): 465-472.
    Search in Google Scholar
  87. Rietjens IM, Boersma MG, van der Woude H, Jeurissen SM, Schutte ME and Alink GM. (2005). Flavonoids and alkenylbenzenes: mechanisms of mutagenic action and carcinogenic risk.(1-2): 124-138.
    Search in Google Scholar
  88. Rietjens IM, Huseiny WA, Boersma MG. (2011). Flavonoids and alkenylbenzenes: New concepts in bioactivation studies.(1-2): 87-95.
    Search in Google Scholar
  89. Rietjens IM, Slob W, Galli C and Silano V. (2008). Risk assessment of botanical preparations intended for use in food and food supplements: emerging issues.(2): 131-136.
    Search in Google Scholar
  90. Rong Y, Yang EB, Zhang K and Mack P. (2000). Quercetin-induced apoptosis in the monoblastoid cell line U937and the regulation of heat shock proteins expression.: 4339-4345.
    Search in Google Scholar
  91. Ross JA. (1998). Maternal diet and infant leukemia: a role for DNA topoisomerase II inhibitors?: 26-28.
    Open DOISearch in Google Scholar
  92. Ross JA and Kasum CM. (2002). Dietary flavonoids: bioavailability, metabolic effects, and safety.: 19-34.
    Search in Google Scholar
  93. Ross JA, Potter JD and Robison LL. (1994). Infant leukemia, topoisomerase II inhibitors, and the MLL gene.: 1678-1680.
    Search in Google Scholar
  94. Russo M, Palumbo R, Tedesco I, Mazzarella G, Russo P, Iacomino G and Russo GL. (1999). Quercetin and anti-CD95(Fas/ Apo1) enhance apoptosis in HPBALL cell line.: 322-328.
    Search in Google Scholar
  95. Rzymowska J, Gawron A, Pawlikowska-Pawlega B, Jakubowicz-Gil J and Wojcierowski J. (1999). The effect of quercetin on induction of apoptosis.: 125-126.
    Search in Google Scholar
  96. Sakihama Y, Cohen MF, Grace SC and Yamasaki H. (2002). Plant phenolic antioxidant and pro-oxidant activities: phenolics-induced oxidative damage mediated by metals in plants.: 67-80.
    Search in Google Scholar
  97. Scalbert A and Williamson G. (2000). Dietary intake and bioavailability of polyphenols.: 2073S-2085S.
    Search in Google Scholar
  98. Schewe T, Steffen Y and Sies H. (2008). How do dietary flavanols improve vascular function? A position paper.(2): 102-106.
    Search in Google Scholar
  99. Schilter B, Andersson C, Anton R, Constable A, Kleiner J, O'Brien J, Renwick AG, Korver O, Smit F and Walker R. (2003). Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplements.(12): 1625-1649.
    Search in Google Scholar
  100. Schroeter H, Spencer JP, Rice-Evans C and Williams RJ. (2001). Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3.: 547-557.
    Search in Google Scholar
  101. So FV, Guthrie N, Chambers AF, Moussa M and Carroll KK. (1996). Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices.: 167-181.
    Search in Google Scholar
  102. Soriani M, Rice-Evans C and Tyrrell RM. (1998). Modulation of the UVA activation of haem oxygenase, collagenase and cyclooxygenase gene expression by (_)-epigallocatechin in human skin cells.: 253-257.
    Search in Google Scholar
  103. Spencer JP, Rice-Evans C and Williams RJ. (2003a). Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and itsmetabolites underlie their action on neuronal viability.(37): 34783-34793.
    Open DOISearch in Google Scholar
  104. Spencer JP, Kuhnle GG, Williams RJ and Rice-Evans C. (2003b). Intracellular metabolism and bioactivity of quercetin and itsmetabolites.: 173-181.
    Open DOISearch in Google Scholar
  105. Steiner C, Peters WH, Gallagher EP, Magee P, Rowland I and Pool-Zobel BL. (2007). Genistein protects human mammary epithelial cells from benzo(a) pyrene-7,8-dihydrodiol-9,10-epoxide and 4-hydroxy-2-nonenal genotoxicity by modulating the glutathione/glutathione S-transferase system.: 738-748.
    Search in Google Scholar
  106. Strick R, Strissel PL, Borgers S, Smith SL and Rowley JD. (2000). Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia.: 4794-4795.
    Search in Google Scholar
  107. Surh YJ, Hurh YJ, Kang JY, Lee E, Kong G and Lee SJ. (1999). Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells.: 1-10.
    Search in Google Scholar
  108. Syed DN, Afaq F, Sarfaraz S, Khan N, Kedlaya R, Setaluri V and Mukhtar H. (2008). Delphinidin inhibits cell proliferation and invasionmodulation of Met receptor phosphorylation.(1): 52-60.
    Search in Google Scholar
  109. Takamura-Enya T, Ishihara J, Tahara S, Goto S, Totsuka T, Sugimura T and Wakabayashi K. (2003). Analysis of estrogenic activity of foodstuffs and cigarette smoke condensates using a yeast estrogen screening method.: 543-550.
    Search in Google Scholar
  110. Talavera S, Felgines C, Texier O, Besson C, Gil-Izquierdo A, Lamaison JL and Remesy C. (2005). Anthocyanin metabolism in rats and their distribution to digestive area, kidney, and brain.: 3902-3908.
    Search in Google Scholar
  111. Tang DG and Porter AT. (1996). Apoptosis: a current molecular analysis.: 117-131.
    Search in Google Scholar
  112. Tang W and Stearns RA. (2001). Heterotropic cooperativity of cytochrome P450 3A4 and potential drug - drug interactions.: 185-198.
    Search in Google Scholar
  113. Tassaneeyakul W, Birkett DJ, Veronese ME, McManus ME, Tukey RH, Quattrochi LC, Gelboin HV and Miners JO. (1993). Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2.: 401-407.
    Search in Google Scholar
  114. Terada T and Inui K. (2007). Gene expression and regulation of drug transporter in the intestine and kidney.: 440-449.
    Search in Google Scholar
  115. Ueda S, Nakamura H, Masutani H, Sasada T, Takabayashi A, Yamaoka Y and Yodoi J. (2001). Baicalin induces apoptosis via mitochondrial pathway as pro-oxidant.: 781-791.
    Search in Google Scholar
  116. van der Woude H, Gliszczynska-Swiglo A, Struijs K, Smeets A, Alink GM and Rietjens IM. (2003). Biphasic modulation of cell proliferation by quercetin at concentrations physiologically relevant in humans.: 41-47.
    Search in Google Scholar
  117. Walle T, Vincent TS and Walle UK. (2003). Evidence of covalent binding of the dietary flavonoid quercetin to DNA and protein in human intestinal and hepatic cells.: 1603-1610.
    Search in Google Scholar
  118. Waller CL and McKinney JD. (1995). Three-dimensional quantitative structure-activity relationships of dioxins and dioxin-like compounds: model validation and Ah receptor characterization.: 847-858.
    Search in Google Scholar
  119. Wang IK, Lin-Shiau SY and Lin JK. (1999). Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells.: 1517-1525.
    Search in Google Scholar
  120. Wang LS and Stoner GD. (2008). Anthocyanins and their role in cancer prevention.: 281-290.
    Search in Google Scholar
  121. Wang Y, Gho WM, Chan FL, Chen S and Leung LK. (2008). The red clover (Trifolium pratense) isoflavone biochanin A inhibits aromatase activity and expression.: 303-310.
    Search in Google Scholar
  122. Wei YQ, Zhao X, Kariya Y, Fukata H, Teshigawara K and Uchida A. (1994). Induction of apoptosis by quercetin: involvement of heat shock protein.: 4952-4957.
    Search in Google Scholar
  123. Wenzel U, Kuntz S, Brendel MD and Daniel H. (2000). Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells.: 3823-3831.
    Search in Google Scholar
  124. Williams RJ, Spencer JP and Rice-Evans C. (2004). Flavonoids: antioxidants or signalling molecules?(7): 838-849.
    Open DOISearch in Google Scholar
  125. Woodward G, Kroon P, Cassidy A and Kay C. (2009). Anthocyanin stability and recovery: implications for the analysis of clinical and experimental samples.: 5271-5278.
    Search in Google Scholar
  126. Yamanaka A, Oda O and Nagao S. (1997). Green tea catechins such as (_)-epicatechin and (_)-epigallocatechin accelerate Cu-induced low density lipoprotein oxidation in propagation phase.: 230-234.
    Search in Google Scholar
  127. Yang GY, Liao J, Kim K, Yurkow EJ and Yang CS. (1998). Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols.: 611-616.
    Search in Google Scholar
  128. You L, Sar M, Bartolucci EJ, McIntyre BS and Sriperumbudur R. (2002). Modulation of mammary gland development in prepubertal male rats exposed to genistein and methoxychlor.: 216-225.
    Search in Google Scholar
  129. Ziberna L, Lunder M, Moze S, Vanzo A, Tramer F, Passamonti S and Drevensek G. (2010). Acute cardioprotective and cardiotoxic effects of bilberry anthocyanins in ischemia-reperfusion injury: beyond concentration-dependent antioxidant activity.(4): 283-94.
    Search in Google Scholar
DOI: https://doi.org/10.2478/v10102-011-0027-5 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853
Journal RSS Feed
Language: English
Page range: 173 - 183
Published on: Feb 6, 2012
Published by: Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
In partnership with: Paradigm Publishing Services
Keywords:
phenolic compounds,
pro-oxidant,
estrogenicity,
cytotoxicity,
apoptosis
Related subjects:
Medicine,
Clinical medicine,
Pharmacology, toxicology

© 2012 Zuzana Kyselova, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons License.

Volume 4 (2011): Issue 4 (December 2011)
Previous article
Next article