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Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 - similarity between human and rat enzymes Cover

Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 - similarity between human and rat enzymes

Open Access
|Nov 2010

References

  1. Dračínská H, Mikšanová M, Svobodová M, Smrček S, Frei E, Schmeiser HH and Stiborová M (2006) Oxidative detoxication of carcinogenic 2-nitroanisole by human, rat and rabbit cytochrome P450. Neuro Endocrinol Lett 27: 9-13.
  2. Garner RC, Martin CN, Clayson DB (1984) (2nd ed. Searle C, Ed.) Carcinogenic aromatic amines and related compounds. Chemical Carcinogens, ACS Monograph 182, Vol. 1: pp. 175-302, American Chemical Society, Washington, DC.
  3. IARC (1989) Diesel and gasoline engine exhausts and some nitroarenes. Monograph on the Evaluation of the carcinogenic risk to humans. Diesel Exhaust and Some Nitroarenes. Vol. 46, IARC, Lyon.
  4. Mikšanová M, Novák P, Frei E and Stiborová M (2004a) Metabolism of carcinogenic 2-nitroanisole by rat, rabbit, porcine and human hepatic cytosol. Collect Czech Chem Commun 69: 589-602.10.1135/cccc20040589
  5. Mikšanová M, Šulc M, Rýdlová H, Schmeiser HH, Frei E and Stiborová M (2004b) Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450. Chem Res Toxicol 17: 663-71.10.1021/tx049972115144223
  6. NTP (1978) Bioassay of o-anisidine hydrochloride for possible carcinogenicity. NTP Technical Report 89, National Institute of Health, US Department of Health and Human Services, Bethesda, MD.
  7. NTP (1993) Toxicology and Carcinogenesis. Studies of 2-nitroanisole. NTP Technical Report 416, National Institute of Health, US Department of Health and Human Services, Bethesda, MD.
  8. Purohit V and Basu A (2000) Mutagenicity of nitroaromatic compounds. Chem Res Toxicol 13: 673-692.10.1021/tx000002x10956054
  9. Stiborová M, Martínek V, Rýdlová H, Hodek P and Frei E (2002) Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes. Cancer Res 62: 5678-5684.
  10. Stiborová M, Martínek V, Schmeiser HH and Frei E (2006) Modulation of CYP1A1-mediated oxidation of carcinogenic azo dye Sudan I and its binding to DNA by cytochrome b5. Neuro Endocrinol Let 27 (Suppl. 2): 35-39.
  11. Stiborová M, Mikšanová M, Smrček S, Bieler CA, Breuer A, Klokow KA, Schmeiser HH, and Frei E (2004) Identification of a genotoxic mechanism for 2-nitroanisole carcinogenicity and of its carcinogenic potential for humans. Carcinogenesis 25:833-40.
  12. Stiborová M, Schmeiser HH and Frei E (1998) To the mechanism of 2-nitroanisole carcinogenicity: in vitro metabolism of 2-nitroanisole mediated by peroxidases and xanthine oxidase. Collect Czech Chem Commun 63: 857-869.10.1135/cccc19980857
DOI: https://doi.org/10.2478/v10102-010-0035-x | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853
Language: English
Page range: 182 - 185
Published on: Nov 1, 2010
Published by: Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2010 Martina Svobodová, Helena Dračínská, Markéta Martínková, Jiří Hudeček, Petr Hodek, Eva Frei, Marie Stiborová, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons License.

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