References
- Bajgar J. (2004) Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis and treatment. Adv Clin Chem 38: 151-216.10.1016/S0065-2423(04)38006-6
- Bajgar J, Fusek J, Jun D, Kuca K, Bartosova L. (2007a) Possibility of pharmacological prophylaxis against highly toxic organophosphates. Chem Listy 101: 81-83.
- Bajgar J, Hajek P, Karasova J, Slizova D, Krs O, Kuca K, Jun D, Fusek J, Capek L. (2007b) Inhibition of acetylcholinesterase in different structures of the rat brain following soman intoxication pretreated with Huperzine A. Int J Mol Sci 8: 1165-1176.10.3390/i8111165
- Bajgar J, Bartosova L, Kuca K, Jun D, Fusek J. (2007c) Changes in cholinesterase activities in the rat blood and brain after sarin intoxication pretreated with butyrylcholinesterase. Drug Chem Toxicol 30: 351-359.10.1080/01480540701522395
- Clement JG, Hansen AS, Boulet CA. (1992). Efficacy of HLö-7 and pyrimidoxime as antidotes of nerve agent poisoning in mice. Arch Toxicol 66: 216-219.
- Doctor BP, Raveh L, Wolfe AD, Maxwell DM, Ashani Y. (1991) Enzymes as pretreatment drugs for organophosphate toxicity. Neurosci Behav Rev 15: 123-128.10.1016/S0149-7634(05)80103-4
- Doctor BP, Maxwell DM, Saxena A. (1997) Preparation and characterization of bioscavengers for possible use against organophosphate toxicity. m-CB Medical Treatment Symposium, 26-30 May 1997, Hradec Kralove. Abstracts p. 17-18.
- Dohnal V, Kuca K, Jun D. (2005) Prediction of a new broad-spectrum reactivator capable to reactivate acetylcholinesterase inhibited by nerve agents. J Appl Biomed 3: 139-145.10.32725/jab.2005.018
- Ekström F, Akfur C, Tunemalm AK, Lundberg S. (2006) Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase. Biochemistry 45: 74-81.10.1021/bi051286t
- Ellman GL, Courtney DK, Andres V Jr, Feartherstone RM. (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7: 88-93.10.1016/0006-2952(61)90145-9
- Fusek J, Bajgar J, Merka V. (2006) Prophylaxe von Vergiftungen mit Nervenkampfstoffen Ergebnisse einer Klinischen Studie. Koord. Sanitatsdienst 24: 48-53.
- Fusek J, Bajgar J, Merka V. (2007) Medikamntose Prophylaxe bei Vergiftungen mit Nervenkampfstoffen. Koord. Sanitatsdienst 25: 41-47.
- Gordon JJ, Leadbetter L, Maidment MP. (1978) The protection of animals against organophosphate poisoning by pretreatment with a carbamate. Toxicol Appl Pharmacol 43: 207-216.10.1016/S0041-008X(78)80045-3
- Gordon RK, Haigh JR, Garcia GE, Feaster SR, Riel MA, Lenz DE. (2005) Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex in vivo exposure to soman. Chem- Biol Interact 157: 239-246.10.1016/j.cbi.2005.10.03116256090
- Kassa J, Vachek J, Bajgar J, Fusek J. (2001) A combination of pyridostigmine with anticholinergic drugs: effective pharmacological pretreatment of soman-poisoned mice. ASA Newslett 84: 16-19.
- Kassa J, Karasova J, Musilek K, Kuca K. (2008) An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice. Toxicology 243: 311-316.10.1016/j.tox.2007.10.01518054821
- Kuca K, Kassa J. (2003) A comparison of the ability of a new bispyridinium oxime - 1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium) butane dibromide and currently used oximes to reactivate nerve agent-inhibited rat brain acetylcholinesterase by in vitro methods. J Enzym Inhib Med Chem 8: 529-535.10.1080/14756360310001605552
- Kuca K, Bielavsky J, Cabal J, Kassa J. (2003) Synthesis of a new reactivator of tabun-inhibited acetylcholinesterase. Bioorg Med Chem Lett 13: 3545-3547.10.1016/S0960-894X(03)00751-0
- Kuca K, Cabal J, Musilek K, Jun D, Bajgar J. (2005) Effective bisquaternary reactivators of tabun-inhibited AChE. J Appl Toxicol 25: 491-495.10.1002/jat.1084
- Kuca K, Jun D, Musilek K. (2006) Structural requirements of acetylcholinesterase reactivators. Mini Rev Med Chem 6: 269-277.10.2174/138955706776073510
- Lallement G, Taille V, Baubichon D, Carpentier P, Collombet JM, Filliat P, et al. (2002) Review of the value of huperzine as pretreatment of organophosphate poisoning. NeuroToxicology 23: 1-5.10.1016/S0161-813X(02)00015-3
- Musilek K, Kuca K, Jun D, Dolezal M. (2006) Synthesis of bispyridinium compounds bearing propane linker and evaluation of their reactivation activity against tabun- and paraoxon-inhibited acetylcholinesterase. Lett Org Chem 3: 831-835.10.2174/157017806779117012
- Musilek K, Holas O, Kuca K, Jun D, Dohnal V, Opletalova V, Dolezal M. (2007a) Novel series of bispyridinium compounds bearing a (Z)-but-2-ene Linker - Synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase. Bioorg Med Chem Lett 17: 3172-3176.10.1016/j.bmcl.2007.03.02517383875
- Musilek K, Holas O, Jun D, Dohnal V, Gunn-Moore F, Opletalova V, Dolezal M, Kuca K. (2007b). Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker - Preparation and reactivation of tabun and paraoxon-inhibited acetylcholinesterase. Bioorg Med Chem 15: 6733-6741.10.1016/j.bmc.2007.08.00217764957
- Musilek K, Jun D, Cabal J, Kassa J, Gunn-Moore F, Kuca K. (2007c) Design of a potent reactivator of tabun-inhibited acetylcholinesterase - synthesis and evaluation of (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide (K203) J Med Chem 50: 5514-5518.10.1021/jm070653r17924614
- Patocka J, Jun D, Bajgar J, Kuca K. (2006) Prophylaxis against nerve agent intoxication. Def Sci J 56: 775-784.10.14429/dsj.56.1941
- Saxena A, Doctor BP, Sun W, Luo C, Bansal R, Naik RS, et al. (2004) HuBChE: A bioscavanger for protection against organophosphate chemical warfare agents. US Army Med Dep J 7: 22-29.
- Sevelova L, Bajgar J, Saxena A, Doctor BP. (2004) Protective effect of equine butyrylcholinesterase in inhalation intoxication of rats with sarin: determination of blood and brain cholinesterase activities. Inhal Toxicol 16: 531-536.10.1080/0895837049044251115204744
- Tallarida R, Murray R. (1987) Manual of Pharmacological Calculation with Computer Programs. Springer-Verlag, New York.