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Comparison of chromosomal aberrations frequency and polymorphism of GSTs genes in workers occupationally exposed to cytostatics or anaesthetics Cover

Comparison of chromosomal aberrations frequency and polymorphism of GSTs genes in workers occupationally exposed to cytostatics or anaesthetics

Open Access
|Sep 2009

References

  1. AHEM. (2007). Metody biologického monitorování genotoxických účinků faktorů prostředí. Cytogenetická analýza periferních lymfocytů. Aktualizace platné standardní metodiky. AHEM. [in Czech] 1/2007, SZÚ, Praha, 30pp
  2. Angelini S, Kumar R, Carbone F, Bermejo JL, Maffei F, Cantelli-Forti G, Hemminki K and Hrelia P. (2008). Inherited susceptibility to bleomycin-induced micronuclei: correlating polymorphisms in GSTT1, GSTM1 and DNA repair genes with mutagen sensitivity. Mutat Res 638: 90-97.
  3. Bilban M, Jakopin CB and Ogrinc D. (2005). Cytogenetic tests performed on operating room personnel (the use of anaesthetic gases). Int Arch Occup Environ Health 78: 60-64.
  4. Burgaz S, Karahalil B, Canhi Z, Terzioglu F, Ancel G, Anzion RB, Bos RP and Hüttner E. (2002). Assessment of genotoxic damage in nurses occupationally exposed to antineoplastics by the analysis of chromosomal aberrations. Hum Exp Toxicol 21: 129-135.
  5. Cavallo D, Ursini LC, Perniconi B, Di Francesco A, Giglio M, Rubino FM, Marinaccio A and Iavicoli S. (2005). Evaluation of genotoxic effects induced exposure to antineoplastic drugs in lymphocytes and exfoliated buccal cells of oncology nurses and pharmacy employees. Mutat Res 587: 45-51.
  6. Cavallo D, Ursini CL, Omodeo-Sale E and Iavicoli S. (2007). Micronucleus induction and FISH analysis in buccal cells and lymphocytes of nurses administering antineoplastic drugs. Mutat Res 628: 11-18.
  7. Connor TH. (2006). Hazardous anticancer drugs in health care:environmental exposure assessment. Ann N Acad Sci 1076: 615-623.
  8. Fransman W, Huizer D, Tuerk J and Kromhout H. (2007a). Inhalation and dermal exposure to eight antineoplastic drugs in an industrial laundry facility. Int Arch Occup Environ Health 80: 396-403.10.1007/s00420-006-0148-x
  9. Fransman W, Roeleveld N, Peelen S, de Kort W, Kromhout H and Heederik D. (2007b). Nurses with dermal exposure to antineoplastic drugs: reproductive outcomes. Epidemiology 18: 112-119.10.1097/01.ede.0000246827.44093.c1
  10. Hoerauf KH, Wiesner G, Schroegendorfer KF, Jobst BP and Spacek A. (1999). Waste anaesthetic gases induce sister chromatid exchanges in lymphocytes of operating room personnel. British J Anaesth 82: 764-766.
  11. Horváthová E. (2008). Trends in the study of genetic susceptibility. Interdisc Toxicol 1: 13-14.
  12. Chandrasekhar M, Rekhadevi PV, Sailaja N, Rahman MF, Reddy JP, Mahboob M and Grover P. (2006). Evaluation of genetic damage in operating room personnel exposed to anaesthetic. Mutagenesis 21: 249-254.
  13. IARC. (1996). Monographs on the evaluation of carcinogenetic risks to humans. Some pharmaceutical drugs. Lyon, International Agency for Research on Cancer 66: 87pp.
  14. Jaloszynski P, Kujawski M, Wasowicz M, Szulc R and Szyfter K. (1999). Genotoxicity of inhalation anesthetics halothane and isoflurane in human lymphocytes studied in vitro using the comet assay. Mutat Res 439: 199-206.
  15. Karahalil B, Yagar S, Bahadir G, Durak P and Sardas S. (2005). Diazepam and propofol used as anesthetics during open-heart surgery do not cause chromosomal aberrations in peripheral blood lymphocytes. Mutat Res 581: 181-186.
  16. Karpinski TM, Kostrzewska-Poczekaj M, Stachecki I, Mikstacki A and Szyfter K. (2005). Genotoxicity of the volatile anaesthetic desflurane in human lymphocytes in vitro, established by comet assay. J Appl Genet 46: 319-324.
  17. Mušák Ľ, Poláková V, Halašová, E, Osina, O, Vodičková L, Buchancová, J, Hudečková H and Vodička P. (2008). Effect of occupational exposure to cytostatics and nucleotide excision repair polymorphisms on chromosomal aberrations frequency. Interdisc Toxicol 2: 13-17.
  18. Musak L, Vodicka P, Klimentová G, Soucek P, Hánová M, Mikulková R, Buchancová J, Vodicková L, Poláková V and Péc M. (2006). Chromosomal damage and polymorphisms of DNA repair genes XRCC1 and XRCC3 in workers exposed to cytostatics. Neuro Endocrinol Lett 27 Suppl 2: 57-60.
  19. Natarajan AT. (2002). Chromosome aberrations:past, present and future. Mutat Res 504: 3-16.
  20. Norppa H, Bonassi S, Hansteen IL, Hagmar L, Strömberg U, Rössner P, Boffetta P, Lindholm C, Gundy S, Lazutka J, Cebulska-Wasilewska A, Fabianova E, Sram RJ, Knudsen LE, Barale R and Fucic A. (2006). Chromosomal aberrations and SCEs as biomarkers of cancer risk. Mutat. Res 600: 37-45.
  21. Pilger A, Köhler I, Stettner H, Mader RM, Rizovski B, Terkola R, Diem E, Franz-Hainzl E, Konnaris CM Valic E and Rüdinger HW. (2000). Long-term monitoring of sister chromatid exchanges and micronucleus frequencies in pharmacy personnel occupationally exposed to cytostatic drugs. Int Arch Occup Environ Health 73: 442-448.
  22. Poljaková J, Eckschlager T, Hřebačková J, Hraběta J, Stiborová M. (2008). The comparison of cytotoxicity of the anticancer drugs doxorubicin and ellipticine to human neuroblastoma cells Interdisc Toxicol 1: 186-189.10.2478/v10102-010-0036-9
  23. Rekhadevi PV, Sailaja N, Chandrasekhar M, Mahboob M, Rahman MF and Grover P. (2007). Genotoxicity assessment in oncology nurses handling anti-neoplastic drugs. Mutagenesis 22: 395-401.
  24. Rombaldi F, Cassini C, Salvator M, Saffi J and Erdtmann B. (2009). Occupational risk assessment of genotoxicity and oxidative stress in workers handling antineoplastic drugs during a working week. Mutagenesis 24: 143-148.
  25. Rozgaj R, Kasuba V and Peric M. (1999). Chromosome aberrations in operating room personnel. Am J Ind Med 35: 642-646.
  26. Rozgaj R and Kasuba V. (2000). Chromosome aberrations and micronucleus frequency in anaesthesiology personnel. Arh Hig Rada Toksikol 51: 361-368.
  27. Rozgaj R, Kasuba V and Jazbec A. (2001). Preliminary study of cytogenetic damage in personnel exposed to anesthetic gases. Mutagenesis 16: 139-143.
  28. Scarpato R, Hirvonen A, Migliore L, Falck G and Norppa H. (1997). Influence of GSTM1 and GSTT1 polymorphisms on the frequency of chromosome aberrations in lymphocytes of smokers and pesticide-exposed greenhouse workers. Mutat. Res 389: 1997, 227-235.10.1016/S1383-5718(96)00152-0
  29. Testa A, Giachelia M, Palma S, Appolloni M, Padua L, Tranfo G, Spagnoli M, Tirindelli D and Cozzi R. (2007). Occupational exposure to antineoplastic agents induces a high level of chromosome damage. Lack of an effect of GST polymorphisms. Toxicol Appl Pharmacol 223: 46-55.
  30. Vorlíček J, Vyzula R and Adam Z. (2000). Praktická onkologie, vybrané kapitoly. Grada Publishing s.r.o. [in Czech] Praha, pp.77-154.
  31. Wiesner G, Hoerauf K, Schroegendorfer K, Sobczynski P, Harth M and Ruediger HW. (2001). High-level, but not low-level, occupational exposure to inhaled anesthetics is associated with genotoxicity in the micronucleus assay. Anesth Analg 92: 118-122.
DOI: https://doi.org/10.2478/v10102-009-0016-0 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853
Language: English
Page range: 190 - 194
Published on: Sep 24, 2009
Published by: Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2009 Ľudovít Mušák, Erika Halašová, Tatiana Matáková, Lucia Letková, Ludmila Vodičková, Janka Buchancová, Henrieta Hudečková, Oto Osina, Pavel Souček, Pavel Vodička, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons License.

Volume 2 (2009): Issue 3 (September 2009)