Have a personal or library account? Click to login
Toxins produced in cyanobacterial water blooms - toxicity and risks Cover

Toxins produced in cyanobacterial water blooms - toxicity and risks

Open Access
|Jun 2009

References

  1. Adamovský O, Kopp, R., Hilscherová K, Babica, P., Palíková M, Pašková V, Navrátil, S., and Bláha, L. (2007) Microcystin kinetics (bioaccumulation, elimination) and biochemical responses in common carp and silver carp exposed to toxic cyanobacterial blooms. Environ Toxicol & Chem 26: 2687-2693.10.1897/07-213.118020691
  2. Babica P, Bláha L, and Maršálek B. (2006) Exploring the natural role of microcystins - a review of effects on photoautotrophic organisms. J Phycol 42: 9-20.10.1111/j.1529-8817.2006.00176.x
  3. Babica P, Hilscherová K, Bártová K, Bláha L, and Maršálek B. (2007) Effects of dissolved microcystins on growth of planktonic photoautotrophs. Phycologia 46: 137-142.10.2216/06-24.1
  4. Bartram J, Carmichael WW, Chorus I, Jones G, and Skulberg OM. (1999) Introduction. In: Toxic cyanobacteria in water: A guide to their public health consequences, monitoring and management. (Chorus I and Bartram J, eds.), pp. 1-14. WHO & E&FN Spon, London10.1201/9781482295061
  5. Beardall J, and Raven JA. (2004) The potential effects of global climate change on microalgal photosynthesis, growth and ecology. Phycologia 43: 26-40.10.2216/i0031-8884-43-1-26.1
  6. Bláhová L, Babica P, Adamovský O, Kohoutek J, Maršálek B, and Bláha L. (2008) Analyses of cyanobacterial toxins (microcystins, cylindrospermopsin) in the reservoirs of the Czech Republic and evaluation of health risks. Environ Chem Lett 6: 223-227.10.1007/s10311-007-0126-x
  7. Bláhová L, Babica P, Maršálková E, Smutná M, Maršálek B, and Bláha L. (2007) Concentrations and seasonal trends of extracellular microcystins in freshwaters of the Czech Republic - results of the national monitoring program. CLEAN - Soil, Air, Water 35: 348-354.10.1002/clen.200700010
  8. Bláhová L, Oravec M, Maršálek B, Šejnohová L, Šimek Z, and Bláha L. (2009) The first occurrence of the cyanobacterial alkaloid toxin cylindrospermin in the Czech Republic as determined by immunochemical and LC/MS methods. Toxicon 53: 519-524.10.1016/j.toxicon.2009.01.01419673098
  9. Bouaicha N, Maatouk I, Plessis MJ, and Perin F. (2005) Genotoxic potential of microcystin-LR and nodularin in vitro in primary cultured rat hepatocytes and in vivo in rat liver. Environ Toxicol 20: 341-34710.1002/tox.2011015892058
  10. Briand J-F, Jacquet S, Bernard C, and Humbert J-F. (2003) Health hazards for terrestrial vertebrates from toxic cyanobacteria in surface water ecosystems. Vet Res 34: 361-377.
  11. Chorus I. (2001) Introduction: Cyanotoxins - research for environmental safety and human health. In: Cyanotoxins - Occurence, Causes, Consequences (Chorus I, ed.), pp. 1-4. Springer-Verlag, Berlin.10.1007/978-3-642-59514-1_1
  12. Chorus I. (2005) Editorial and summary. In: Current approaches to cyanotoxin risk assessment, risk management and regulations in different countries (Chorus I, ed.), pp. 1-8. Federal Environmental Agency (Umweltbundesamt), Berlin.
  13. Chorus I, and Bartram J. eds. (1999) Toxic Cyanobacteria in Water: A guide to their public health consequences, monitoring and management. E&FN Spon, London.10.1201/9781482295061
  14. Codd GA, Lindsay J, Young FM, Morrison LF, and Metcalf JS. (2005a) Cyanobacterial Toxins. In: Harmful Cyanobacteria (Huisman J, Matthijs HCP and Visser PM, eds.), pp. 1-23. Springer-Verlag.10.1007/1-4020-3022-3_1
  15. Codd GA, Morrison LF & Metcalf JS. (2005b) Cyanobacterial toxins: risk management for health protection. Toxicology and Applied Pharmacology 203: 264-272.10.1016/j.taap.2004.02.016
  16. Dawson RM. (1998) The toxicology of microcystins. Toxicon 36: 953-962.
  17. Dietrich D, and Hoeger S. (2005) Guidance values for microcystins in water and cyanobacterial supplement products (blue-green algal supplements): a reasonable or misguided approach? Toxicology and Applied Pharmacology 203: 273-289.10.1016/j.taap.2004.09.005
  18. Ding W-X, and Ong CN. (2003) Role of oxidative stress and mitochondrial changes in cyanobacteria-induced apoptosis and hepatotoxicity - MiniReview. FEMS Microbiology Letters 220: 1-7.
  19. Duy TN, Lam PKS, Shaw GR, and Connell DW. (2000) Toxicology and risk assessment of freshwater cyanobacterial (blue-green algal) toxins in water. Rev Environ Contam Toxicol 163: 113-186.10.1007/978-1-4757-6429-1_3
  20. Edwards C, Beattie KA, Scrimgeour CM, and Codd GA. (1992) Identification of Anatoxin-a in Benthic Cyanobacteria (Blue-Green-Algae) and in Associated Dog Poisonings at Loch Insh, Scotland. Toxicon 30: 1165-1175.10.1016/0041-0101(92)90432-5
  21. Falconer I. (2006) Cyanobacterial Toxins of Drinking Water Supplies: cylindrospermopsins and microcystins. CRC Press, Boca Raton, Florida, USA.10.1002/tox.20194
  22. Fawell JK, Mitchell RE, Everett DJ, and Hill RE. (1999) The toxicity of cyanobacterial toxins in the mouse: I Microcystin-LR. Human & Experimental Toxicology 18: 162-167.10.1177/096032719901800305
  23. Fu W-Y, Chen JP, Wang X-M, and Xu LH. (2005) Altered expression of p53, Bcl-2 and Bax induced by microcystin-LR in vivo and in vitro. Toxicon 46: 171-177.
  24. Gehringer MM. (2004) Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response. FEBS Letters 557: 1-8.
  25. Guzman RE, Solter PF, and Runnegar MT. (2003) Inhibition of nuclear protein phosphatase activity in mouse hepatocytes by the cyanobacterial toxin microcystin-LR. Toxicon 41: 773-781.10.1016/S0041-0101(03)00030-8
  26. Humpage AR, and Falconer IR. (1999) Microcystin-LR and liver tumor promotion: Effects on cytokinesis, ploidy, and apoptosis in cultured hepatocytes. Environmental Toxicology 14: 61-75.
  27. Humpage AR, Fenech M, Thomas P, and Falconer IR. (2000) Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 472: 155-161.10.1016/S1383-5718(00)00144-3
  28. Ikawa M, Sasner JJ, and Haney JF. (1997) Inhibition of Chlorella growth by degradation and related products of linoleic and linolenic acids and the possible significance of polyunsaturated fatty acids in phytoplankton ecology. Hydrobiologia 356: 143-148.10.1023/A:1003103726520
  29. Mez K, Beattie KA, Codd GA, Hanselmann K, Hauser B, Naegeli H, and Preisig HR. (1997) Identification of a microcystin in benthic cyanobacteria linked to cattle deaths on alpine pastures in Switzerland. European Journal of Phycology 32: 111-117.10.1080/09670269710001737029
  30. Oberemm A, Heinze R, Papendorf O, and Fastner J. (2001) Significance of unidentified toxic compounds and approaches to their identification. In: Cyanotoxins - Occurence, Causes, Consequences (Chorus I, ed.), pp. 286-295. Springer-Verlag, Berlin.
  31. Rapala J, Robertson A, Negri AP, Berg KA, Tuomi P, Lyra C, Erkomaa K, Lahti K, Hoppu K, and Lepisto L. (2005) First report of saxitoxin in Finnish lakes and possible associated effects on human health. Environmental Toxicology 20: 331-340.10.1002/tox.2010915892061
  32. Reinikainen M, Meriluoto JAO, Spoof L, and Harada K. (2001) The toxicities of a polyunsaturated fatty acid and a microcystin to Daphnia magna. Environmental Toxicology 16: 444-448.10.1002/tox.1000311594032
  33. Sivonen K, and Jones G. (1999) Cyanobacterial toxins. In: Toxic Cyanobacteria in Water: A Guide to Public Health Significance, Monitoring and Management (Chorus I and Bartram J, eds.), pp. 41-111. E&FN Spon, London.
  34. Watson SB. (2003) Cyanobacterial and eukaryotic algal odour compounds: signals or by-products? A review of their biological activity. Phycologia 42: 332-350.
  35. Welker M, and von Dohren H. (2006). Cyanobacterial peptides - Nature's own combinatorial biosynthesis. FEMS Microbiol Rev 30: 530-563.
  36. WHO (1998a) Guidelines for drinking water quality. World Health Organisation, Geneva.
  37. WHO (1998b) Chapter 7: Freshwater algae and cyanobacteria. In: Guidelines for Safe Recreational-water Environments, Volume 1: Coastal and Freshwaters, pp. 125-209. World Health Organization.
  38. Wiegand C, and Pflugmacher S. (2005) Ecotoxicological effects of selected cyanobacterial secondary metabolites a short review. Toxicology and Applied Pharmacology 203: 201-218.10.1016/j.taap.2004.11.00215737675
  39. Xie LQ, Xie P, Guo LG, Li L, Miyabara Y, and Park HD. (2005) Organ distribution and bioaccumulation of microcystins in freshwater fish at different trophic levels from the eutrophic Lake Chaohu, China. Environmental Toxicology 20: 293-300.10.1002/tox.2012015892067
  40. Yoshida T, Makita Y, Nagata S, Tsutsumi T, Yoshida F, Sekijima M, Tamura SI, and Ueno Y. (1997) Acute oral toxicity of microcystin-LR, a cyanobacterial hepatotoxin, in mice. Natural Toxins 5: 91-95.10.1002/nt.19407554
  41. Yu SZ. (1995) Primary Prevention of Hepatocellular-Carcinoma. Journal of Gastroenterology and Hepatology 10: 674-682.
  42. Zhou L, Yu H, and Chen K. (2002) Relationship between microcystin in drinking water and colorectal cancer. Biomedical and Environmental Sciences 15: 166-171.
  43. Zurawell RW, Chen HR, Burke JM, and Prepas EE. (2005) Hepatotoxic cyanobacteria: A review of the biological importance of microcystins in freshwater environments. Journal of Toxicology and Environmental Health-Part B-Critical Reviews 8: 1-37.10.1080/1093740059088941215762553
DOI: https://doi.org/10.2478/v10102-009-0006-2 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853
Language: English
Page range: 36 - 41
Published on: Jun 19, 2009
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2009 Luděk Bláha, Pavel Babica, Blahoslav Maršálek, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons License.

Volume 2 (2009): Issue 2 (June 2009)