References
- Acosta-Martinez, M., Levine, J.E. (2007). Regulation of Katp channel sub- unit gene expression by hyperglycemia in the mediobasal hypothalamus of female rats. Amer. J. Physiol. Endocrinol. Metab., 292, E1801-E1807.
- Benoit, S.C., Kemp, C.J., Elias, C.F., Abplanalp, W., Herman, J.P., Migrenne, S., Lefevre, A., Cruciani-Guglielmacci, C., Magnan, C., Yu, F., Niswensder, K., Irani, B.G., Holland, W.L., Clegg, D.J. (2009). Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents. J. Clin. Invest., 119, 2277-2589.
- Blouet, C., Jo, Y., Li, X., Schwartz, G.J. (2009). Mediobasal hypothalamic leucine sensing regulates food intake through activation of a hypothalamus-brainstem circuit. J. Neurosci., 29, 8302-8311.
- Blouet, C., Schwartz, G.J. (2010). Hypothalamic nutrient sensing in the control of energy homeostasis. Behav. Brain Res., 209, 1-12.
- Chen, H., Simar, D., Lambert, K., Mercier, J., Morris, M.J. (2008). Maternal and postnatal overnutrition differentially impact appetite regulators and fuel metabolism. Endocrinology, 149, 5348-5356.
- Cheng, Y., Meng, Q., Xia, T., Wang, C., Li, H., Huang, Z., Chen, S., Xiao, F., Du, Y., Guo, F. (2010). Leucine deprivation decreases fat mass by stimulation of lipolysis in white adipose tissue and upregulation of uncoupling protein 1 (UCP1) in brown adipose tissue. Diabetes, 59, 17-25.
- Cheng, Y., Zhang, Q., Meng, Q., Xia, T., Huang, Z., Wang, C., Liu, B., Chen, S., Xiao, F., Du, Y., Guo, F. (2011). Leucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous system. Mol. Endocrinol., 25, 1624-1635.
- Cummmings, D.E. (2009). Endocrine mechanisms mediating remission of diabetes after gastric bypass surgery. Int. J. Obes. (London), 33 Supp 1, S33-S40.
- Drake, A.J., Reynolds, R.M. (2010). Impact of maternal obesity on offspring obesity and cardiometabolic disease risk. Reproduction, 140, 387-398.
- Figlewicz, D.P. (2003). Adiposity signals and food reward: Expanding the CNS roles of insulin and leptin. Amer. J. Physiol. Regul. Integr. Comp. Physiol., 284, R882-R892.
- Lam, T.K. Neuronal regulation of homeostasis by nutrient sensing. Nat. Med., 16, 392-395, 2010.
- Lam, T.K., Gutierrez-Juarez, R., Pocai, A., Rossetti, L. (2005). Regulation of blood glucose by hypothalamic pyruvate metabolism. Science, 309, 943-947.
- Lam, T.K., Schwartz, G.J., Rosetti, L. (2005). Hypothalamic sensing of fatty acids. Nat. Neurosci., 8, 579-584.
- Levin, B.E. (2002). Glucosensing neurons: The metabolic sensors of the brain? Diabetes Nutr. Metab., 15, 274-281.
- Levin, B.E., Dunn-Meynell, A.A., Routh, V.H. (2002). CNS sensing and regulation of peripheral glucose levels. Int. Rev. Neurobiol., 51, 219-258.
- Morton, G.J., Gelling, R.W., Niswender, K.D., Morrison, C.D., Rhodes, C.J., Schwartz, M.W. (2005). Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell Metab., 2, 411-420.
- Nair, K.S., Schwartz, R.G., Welle, S. (1992). Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans. Amer. J. Physiol., 263, E928-E934.
- Obici, S., Zhang, B.B., Karkanias, G., Rossetti, L. (2002). Hypothalamic insulin signaling is required for inhibition of glucose production. Nat. Med., 8, 1376-1382.
- Pillot, B., Duraffourd, C., Begeot, M., Joly, A., Luquet, S., Houberdon, I., Naville, D., Vigier, M., Gautier-Stein, A., Magnan, C., Mithieux, G. (2011). Role of hypothalamic melanocortin system in adaptation of food intake to food protein increase in mice. PLoS ONE 6, e19107.
- Rasoamanana, R., Darcel, N., Fromentin, G., Tome, D. (2012). Nutrient sensing and signalling by the gut. Proc. Nutr. Soc., 27, 1-10.
- Ross, R., Wang, P.Y., Chari, M., Lam, C.K., Caspi, L., Ono, H., Muse, E.D., Li, X., Gutierrez-Juarez, R., Light, P.E., Schwartz, G.J., Rossetti, L., Lam, T.K. (2008). Hypothalamic protein kinase C regulates glucose production. Diabetes, 57, 2061-2065.
- Rother, E., Konner, A.C., Bruning, J.C. (2008). Neurocircuits integrating hormone and nutrient signaling in control of glucose metabolism. Amer. J. Physiol. Endocrinol. Metab., 294, E810-E816.
- Zheng, H., Lenard, N., Shin, A., Berthoud, H.R. (2009). Appetite control and energy balance regulation in the modern world: Reward-driven brain overrides repletion signals. Int. J. Obes. (London), 33, S8-S13.