Nutritional Factors in Central Metabolic Regulation

Alfrēds Jānis Sīpols

doi:10.2478/v10046-012-0002-3

.blurhash-client-img { display: none !important; }

Nutritional Factors in Central Metabolic Regulation

Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.

Volume 66 (2012): Issue 3 (August 2012)

By: Alfrēds Jānis Sīpols

Open Access

|Dec 2012

Acosta-Martinez, M., Levine, J.E. (2007). Regulation of Katp channel sub- unit gene expression by hyperglycemia in the mediobasal hypothalamus of female rats. Amer. J. Physiol. Endocrinol. Metab., 292, E1801-E1807.
Search in Google Scholar
Benoit, S.C., Kemp, C.J., Elias, C.F., Abplanalp, W., Herman, J.P., Migrenne, S., Lefevre, A., Cruciani-Guglielmacci, C., Magnan, C., Yu, F., Niswensder, K., Irani, B.G., Holland, W.L., Clegg, D.J. (2009). Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents. J. Clin. Invest., 119, 2277-2589.
Open DOI Search in Google Scholar
Blouet, C., Jo, Y., Li, X., Schwartz, G.J. (2009). Mediobasal hypothalamic leucine sensing regulates food intake through activation of a hypothalamus-brainstem circuit. J. Neurosci., 29, 8302-8311.
Open DOI Search in Google Scholar
Blouet, C., Schwartz, G.J. (2010). Hypothalamic nutrient sensing in the control of energy homeostasis. Behav. Brain Res., 209, 1-12.
Open DOI Search in Google Scholar
Chen, H., Simar, D., Lambert, K., Mercier, J., Morris, M.J. (2008). Maternal and postnatal overnutrition differentially impact appetite regulators and fuel metabolism. Endocrinology, 149, 5348-5356.
Open DOI Search in Google Scholar
Cheng, Y., Meng, Q., Xia, T., Wang, C., Li, H., Huang, Z., Chen, S., Xiao, F., Du, Y., Guo, F. (2010). Leucine deprivation decreases fat mass by stimulation of lipolysis in white adipose tissue and upregulation of uncoupling protein 1 (UCP1) in brown adipose tissue. Diabetes, 59, 17-25.
Open DOI Search in Google Scholar
Cheng, Y., Zhang, Q., Meng, Q., Xia, T., Huang, Z., Wang, C., Liu, B., Chen, S., Xiao, F., Du, Y., Guo, F. (2011). Leucine deprivation stimulates fat loss via increasing CRH expression in the hypothalamus and activating the sympathetic nervous system. Mol. Endocrinol., 25, 1624-1635.
Open DOI Search in Google Scholar
Cummmings, D.E. (2009). Endocrine mechanisms mediating remission of diabetes after gastric bypass surgery. Int. J. Obes. (London), 33 Supp 1, S33-S40.
Search in Google Scholar
Drake, A.J., Reynolds, R.M. (2010). Impact of maternal obesity on offspring obesity and cardiometabolic disease risk. Reproduction, 140, 387-398.
Open DOI Search in Google Scholar
Figlewicz, D.P. (2003). Adiposity signals and food reward: Expanding the CNS roles of insulin and leptin. Amer. J. Physiol. Regul. Integr. Comp. Physiol., 284, R882-R892.
Open DOI Search in Google Scholar
Lam, T.K. Neuronal regulation of homeostasis by nutrient sensing. Nat. Med., 16, 392-395, 2010.
Open DOI Search in Google Scholar
Lam, T.K., Gutierrez-Juarez, R., Pocai, A., Rossetti, L. (2005). Regulation of blood glucose by hypothalamic pyruvate metabolism. Science, 309, 943-947.
Open DOI Search in Google Scholar
Lam, T.K., Schwartz, G.J., Rosetti, L. (2005). Hypothalamic sensing of fatty acids. Nat. Neurosci., 8, 579-584.
Open DOI Search in Google Scholar
Levin, B.E. (2002). Glucosensing neurons: The metabolic sensors of the brain? Diabetes Nutr. Metab., 15, 274-281.
Search in Google Scholar
Levin, B.E., Dunn-Meynell, A.A., Routh, V.H. (2002). CNS sensing and regulation of peripheral glucose levels. Int. Rev. Neurobiol., 51, 219-258.
Open DOI Search in Google Scholar
Morton, G.J., Gelling, R.W., Niswender, K.D., Morrison, C.D., Rhodes, C.J., Schwartz, M.W. (2005). Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell Metab., 2, 411-420.
Open DOI Search in Google Scholar
Nair, K.S., Schwartz, R.G., Welle, S. (1992). Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans. Amer. J. Physiol., 263, E928-E934.
Open DOI Search in Google Scholar
Obici, S., Zhang, B.B., Karkanias, G., Rossetti, L. (2002). Hypothalamic insulin signaling is required for inhibition of glucose production. Nat. Med., 8, 1376-1382.
Open DOI Search in Google Scholar
Pillot, B., Duraffourd, C., Begeot, M., Joly, A., Luquet, S., Houberdon, I., Naville, D., Vigier, M., Gautier-Stein, A., Magnan, C., Mithieux, G. (2011). Role of hypothalamic melanocortin system in adaptation of food intake to food protein increase in mice. PLoS ONE 6, e19107.
Open DOI Search in Google Scholar
Rasoamanana, R., Darcel, N., Fromentin, G., Tome, D. (2012). Nutrient sensing and signalling by the gut. Proc. Nutr. Soc., 27, 1-10.
Open DOI Search in Google Scholar
Ross, R., Wang, P.Y., Chari, M., Lam, C.K., Caspi, L., Ono, H., Muse, E.D., Li, X., Gutierrez-Juarez, R., Light, P.E., Schwartz, G.J., Rossetti, L., Lam, T.K. (2008). Hypothalamic protein kinase C regulates glucose production. Diabetes, 57, 2061-2065.
Open DOI Search in Google Scholar
Rother, E., Konner, A.C., Bruning, J.C. (2008). Neurocircuits integrating hormone and nutrient signaling in control of glucose metabolism. Amer. J. Physiol. Endocrinol. Metab., 294, E810-E816.
Open DOI Search in Google Scholar
Zheng, H., Lenard, N., Shin, A., Berthoud, H.R. (2009). Appetite control and energy balance regulation in the modern world: Reward-driven brain overrides repletion signals. Int. J. Obes. (London), 33, S8-S13.
Open DOI Search in Google Scholar