Abstract
The purpose of the study was to determine the relationships between emotional distress and pain syndrome, its characteristic parameters and impact on the quality of life in patients with chronic low back pain. The study included 110 patients, mean age 44.2 ± 8.0 years, with clinical diagnosis of lumbar spine disk pathology with chronic low back pain syndrome. The results showed that the studied patients differed by their emotional state. Emotional distress was associated with high intensity and specific symptoms of low back pain syndrome. Musculoskeletal dysfunction was associated with both physical and psychoemotional factors. The interaction of chronic low back pain syndrome complexity and biopsyhosocial factors is shown by a correlation between cytokines IL-10 and IL-8 level in blood serum and both pain intensity and duration, characteristics of emotional and physical status, and level of physical activities.