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Protocol for purification of a rat blood serum protein fraction enriched in gamma-butyrobetaine esterase activity Cover

Protocol for purification of a rat blood serum protein fraction enriched in gamma-butyrobetaine esterase activity

Open Access
|Nov 2009

References

  1. Bagdoniene, L., Labeikyte, D., Kalviņs, I., Borutinskaite, V., Prokofjevs, A., Trapencieris, P., Juodka, B., Sjakste, N. (2009). Rat serum carboxyl-esterase partly hydrolyses gamma-butyrobetaine esters. Arh. Hig. Rada Toksikol., 60, 147-156.10.2478/10004-1254-60-2009-1915
  2. Bradford, M.M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.10.1016/0003-2697(76)90527-3
  3. Connelly, P.W., Maguire, G.F., Draganov, D.I. (2004). Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity. J. Lipid Res., 45, 561-566.10.1194/jlr.M300464-JLR200
  4. Cuatrecasas, P. (1970). Protein purification by affinity chromatography: Derivatizations of agarose and polyacrylamide beads. J. Biol. Chem., 245, 3059-3065.10.1016/S0021-9258(18)63022-4
  5. Dambrova, M., Chlopicki, S., Liepinsh, E., Kirjanova, O., Gorshkova, O., Kozlovski, V.I., Uhlen, S., Liepina, I., Petrovska, R., Kalvinsh, I. (2004). The methylester of gamma-butyrobetaine, but not gamma-butyrobetaine itself, induces muscarinic receptor-dependent vasodilatation. Naunyn Schmiedebergs Arch. Pharmacol., 369, 533-539.
  6. Hosein, E.A., Booth, S.J., Gasoi, I., Kato, G. (1967). Neuromuscular blocking activity and other pharmacologic properties of various carnitine derivatives. J. Pharmacol. Exp. Ther., 156, 565-572.
  7. Hosein, E.A., Kato, A., Vine, E., Hill, A.M. (1970). The identification of acetyl-L-carnitylcholine in rat brain extracts and the comparison of its cholinomimetic properties with acetylcholine. Can. J. Physiol Pharmacol., 48, 709-722.10.1139/y70-103
  8. Hosein, E.A., Pang, D., Tesfaye, Y. (1971). Some biochemical actions of carnitylcholine, a neuromuscular blocking agent. Biochem. Pharmacol., 20, 3385-3395.10.1016/0006-2952(71)90443-6
  9. Hosein, E.A., Proulx, P. (1964). Acetylcholine-like activity in subcellular particles isolated from rat brain. Arch. Biochem. Biophys., 106, 267-274.10.1016/0003-9861(64)90187-0
  10. Kalvinsh, I., Gutcaits, A., Bagdoniene, L., Labeikyte, D., Trapencieris, P., Sjakste, N. (2006). Hypothetical gamma-butyrobetaine esterase-dependent signal transduction system: Possible link to mildronate action. Med. Hypotheses Res., 3, 803-812.
  11. Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227, 680-685.10.1038/227680a05432063
  12. Lockridge, O., Schopfer, L.M., Winger, G., Woods, J.H. (2005). Large scale purification of butyrylcholinesterase from human plasma suitable for injection into monkeys; a potential new therapeutic for protection against cocaine and nerve agent toxicity. J. Med. Chem. Biol. Radiol. Def., 3, 1-23.
  13. Morgan, E.W., Yan, B., Petersen, D. R., Greenway, D., Parkinson, A. (1994). Purification and characterization of two rat liver microsomal carboxyl-esterases (hydrolases A and B). Arch. Biochem. Biophys. 315, 495-512.10.1006/abbi.1994.15317986098
  14. Nigg, H.N., Knaak, J.B. (2000). Blood cholinesterases as human biomarkers of organophosphorus pesticide exposure. Rev. Environ. Contam. Toxicol., 163, 29-111.10.1007/978-1-4757-6429-1_210771584
  15. Orbidāne, O., Meirena, D., Pugovičs, O., Dzintare, M., Sjakste, J., Kalviņš, I., Sjakste, N. (2004). Gamma-butyrobetaine esterase activity in rat blood serum. Proc. Latv. Acad. Sci. B, 58, 98-102.
  16. Sjakste, N., Kalvinsh, I. (2006). Mildronate: An antiischemic drug with multiple indications. Pharmacologyonline, 1, 1-18.
  17. Sjakste, N., Gutcaits, A., Kalvinsh, I. (2005a). Mildronate: An antiischemic drug for neurological indications CNS Drug Reviews, 11, 151-168.10.1111/j.1527-3458.2005.tb00267.x674175116007237
  18. Sjakste, N., Sjakste, J., Boucher, J.L., Baumane, L., Sjakste, T., Dzintare, M., Meirena, D., Sharipova, J., Kalvinsh, I. (2005b). Putative role of nitric oxide synthase isoforms in the changes of nitric oxide concentration in rat brain cortex and cerebellum following sevoflurane and isoflurane anaesthesia. Eur. J. Pharmacol, 513, 193-205.10.1016/j.ejphar.2005.03.01415862801
  19. Thomizek, W.D., Strack, E., Lorenz, J. (1963). Über den Einfluß einiger Derivate aliphatischen Trimethylbetaine auf die Acetylcholine-esterase und über die Hydrolyse von Betainestern. Acta Biol. Med. Germ., 11, 353-355.
  20. Wheelock, C.E., Phillips, B.M., Anderson, B.S., Miller, J.L., Miller, M.J., Hammock, B.D. (2008). Applications of carboxylesterase activity in environmental monitoring and toxicity identification evaluations (TIEs). Rev Environ Contam Toxicol, 195, 117-178.10.1007/978-0-387-77030-7_518418956
  21. Абдикалиев Н. А., Калвиньш И. И., Меерсон Ф. З. (1991). Антиаритми-ческое действие синтетического аналога ацетилхолина на нарушения сердечного ритма, вызванные хлоридом кальция и строфантином. [The antiarrhythmic action of the synthetic acetylcholine analogue EDIHYP in calcium chloride-and strophanthin-induced heart rhythm disorders]. Фармакол. Токсикол., 54, 25 - 28 (in Russian).
  22. Меерсон Ф. З, Абдикалиев Н. А., Калвиньш И. И., Вовк В. И. (1991a). Биоэлектрический механизм антиаритмического действия синтети-ческого аналога ацетилхолина ЭДИГИП [Bioelectrical the anti-arrhythmia effect of a synthetic acetylcholine analogue EDIHYP]. Кардиология, 31, 52 - 55 (in Russian).
  23. Меерсон Ф. З, Калвиньш И. И., Абдикалиев Н. А. (1991b). Устранение нарушений электрической стабильности сердца и аритмии с помощью синтетического аналога ацетилхолина [Correction of tric stability of the heart and arrhythmia by using a synthetic analogue of acetylcholine]. Бюлл. Эксп. Биол. Мед., 111, 13-16 (in Russian).
DOI: https://doi.org/10.2478/v10046-009-0023-8 | Journal eISSN: 2255-890X | Journal ISSN: 1407-009X
Language: English
Page range: 93 - 99
Published on: Nov 6, 2009
In partnership with: Paradigm Publishing Services
Publication frequency: 6 issues per year

© 2009 Lida Bagdonienė, Danutė Labeikytė, Ivars Kalviņš, Benediktas Juodka, Nikolajs Sjakste, published by Latvian Academy of Sciences
This work is licensed under the Creative Commons License.

Volume 63 (2009): Issue 3 (June 2009)