Hypergonadotropic Hypogonadism, Progressive Early-Onset Spinocerebellar Ataxia, and Late-Onset Sensorineural Hearing Loss: Case Report and Literature Review

E Sarikaya; C Ensert; H Gulerman

doi:10.2478/v10034-011-0050-z

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Hypergonadotropic Hypogonadism, Progressive Early-Onset Spinocerebellar Ataxia, and Late-Onset Sensorineural Hearing Loss: Case Report and Literature Review

Balkan Journal of Medical Genetics

Volume 14 (2011): Issue 2 (December 2011)

By: E Sarikaya, C Ensert and H Gulerman

Open Access

|Dec 2011

Abstract

The association of ataxia, hypergonadotropic hypogonadism and hearing loss is extremely rare. Considerable heterogeneity exists in the literature of the neurological manifestations, age of onset, clinical severity and associated abnormalities. We describe a 24-year-old woman with secondary hypergonadotropic amenorrhea, early-onset progressive spinocerebellar ataxia (SCA), late-onset sensorineural hearing loss and normal intelligence and compare it with reported cases.

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Articles in this issue

DOI: https://doi.org/10.2478/v10034-011-0050-z | Journal eISSN: 2199-5761 | Journal ISSN: 1311-0160

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Language: English

Page range: 77 - 88

Published on: Dec 8, 2011

Published by: Macedonian Academy of Sciences and Arts

In partnership with: Paradigm Publishing Services

Publication frequency: 2 issues per year

Keywords:

Cerebellar ataxia,

Hearing loss,

Sensorineural,

Premature ovarian failure

Related subjects:

Medicine,

Basic medical science,

Basic medical science, other

© 2011 E Sarikaya, C Ensert, H Gulerman, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons License.

Volume 14 (2011): Issue 2 (December 2011)