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Web-Based Software for Storage, Statistical Processing and Analysis of SNP Data in Studies on Complex Disorders Cover

Web-Based Software for Storage, Statistical Processing and Analysis of SNP Data in Studies on Complex Disorders

By: E Betcheva,  C Betchev and  D Toncheva  
Open Access
|Oct 2009

Abstract

Single nucleotide polymorphisms (SNPs) have become a very powerful tool for molecular genetics studies. Public databases provide information on over 10 million polymorphisms in the human genome. The candidate gene approach and genomewide association studies through SNP analysis have opened a new avenue for defining the genetics of complex disorders. However, analysis of large numbers of SNPs is time-consuming, cost-intensive, and requires huge experimental and statistical resources in association studies. We have developed a web-based product that facilitates the processing and statistical analysis of SNP-genotyping data for casecontrol association studies and provides for custom design, a structured database and practical export layout. Here we describe the software product database and how it helps in high-speed comprehensive SNP analysis.

Language: English
Page range: 9 - 14
Published on: Oct 9, 2009
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2009 E Betcheva, C Betchev, D Toncheva, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons License.

Volume 12 (2009): Issue 1 (June 2009)