Factor VIII-Intron 1 Inversion of Hemophilia A Patients In West Anatolia

Pehlivan, M; Pehlivan, S; Buyukkececi, F; Çagirgan, S; Yilmaz, M; Bedii, Omay; Tombuloğlu, M; Kavakli, K

doi:10.2478/v10034-007-0009-2

Abstract

Hemophilia A (HA) is a hereditary, life-threatening and disabling disorder. In this study, we have examined 61 unrelated HA patients in order to identify the incidence of the intron 1 factor VIII (FVIII) gene inversion in the West Anatolian population. According to the results of DNA analyses of the 61 HA patients, no intron 1 inversion of the FVIII gene was found.

References

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Factor VIII-Intron 1 Inversion of Hemophilia A Patients In West Anatolia

Abstract

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