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Genetic markers in oligodendroglial tumours Cover

Genetic markers in oligodendroglial tumours

Open Access
|Mar 2010

Abstract

Background. Oliogodendrogliomas are brain tumours composed of the cells resembling oligodendrocytes. They represent the third most common glial tumour, comprising 2.5% of all primary brain tumours and 5-20% of all gliomas.

Conclusions. Oligodendroglial tumours with 1p and 19q loss demonstrate a better overall prognosis due to more indolent clinical behaviour and higher sensitivity to treatment. Additionally, 1p and 19q loss is a marker of clinical utility, helping to assess tumour sensitivity to chemotherapy and harbouring the potential for improving the diagnosis and survival of oligodendroglioma patients as well as future clinical practice.

DOI: https://doi.org/10.2478/v10019-010-0007-y | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 13 - 18
Published on: Mar 18, 2010
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2010 Tomaz Velnar, Uros Smrdel, Mara Popovic, Gorazd Bunc, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons License.

Volume 44 (2010): Issue 1 (March 2010)