How well are clinical gross tumor volume DVHs approximated by an analytical function?

Pavel Stavrev; Colleen Schinkel; Nadia Stavreva; B. Falloned

doi:10.2478/v10019-009-0016-x

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How well are clinical gross tumor volume DVHs approximated by an analytical function?

Radiology and Oncology

Volume 43 (2009): Issue 2 (June 2009)

By: Pavel Stavrev, Colleen Schinkel, Nadia Stavreva and B. Falloned

Open Access

|Jun 2009

Abstract

The dose heterogeneity in the tumor is often described as being normally distributed. Besides the normal distribution we propose the Fermi function describing Fermi statistics as a possible dose heterogeneity descriptor. In order to demonstrate the adequacy of the proposed functions as dose distribution descriptors 30 clinical gross tumor volume (GTV) dose-volume histograms (DVHs) are gathered and fit with the examined functions.

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Articles in this issue

DOI: https://doi.org/10.2478/v10019-009-0016-x | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099

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Language: English

Page range: 132 - 135

Published on: Jun 8, 2009

Published by: Association of Radiology and Oncology

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

dose-volume histograms,

gross tumor volume,

Gaussian and Fermi statistics

Related subjects:

Medicine,

Clinical medicine,

Internal medicine,

Haematology, oncology,

Radiology

© 2009 Pavel Stavrev, Colleen Schinkel, Nadia Stavreva, B. Falloned, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons License.

Volume 43 (2009): Issue 2 (June 2009)