Have a personal or library account? Click to login
Ecotoxicologically relevant cyclic peptides from cyanobacterial bloom (Planktothrix rubescens) - a threat to human and environmental health Cover

Ecotoxicologically relevant cyclic peptides from cyanobacterial bloom (Planktothrix rubescens) - a threat to human and environmental health

Radiology and Oncology
Volume 42 (2008): Issue 2 (June 2008)
By: Bojan Sedmak,  Tina Eleršek,  Olga Grach-Pogrebinsky,  Shmuel Carmeli,  Nataša Sever and  Tamara Lah  
Open Access
|May 2008

References

  1. Gomont MM. Monographie des Oscillariées (Nostocacées, homocystées). Ann Sci Nat Bot Ser 7 1892;15:263-368; 16: 91-264.
    Search in Google Scholar
  2. Harada K-I, Matsuura K, Suzuki M, Oka H, Watanabe MF, Oishi S, et al. Analysis and purification of toxic peptides from cyanobacteria by reversed-phase high-performance chromatography. J Chromatogr A 1988; 448: 275-83.10.1016/S0021-9673(01)84589-1
    Search in Google Scholar
  3. Harada K-I, Suzuki M, Dahlem AM, Beasley VR, Carmichael WW, Rinehart KL. Improved method for purification of toxic peptides produced by cyanobacteria. Toxicon 1988; 26: 433-9.10.1016/0041-0101(88)90182-1
    Search in Google Scholar
  4. Vollenweider RA. Primary Production in Aquatic Environments. Int Biol Prog Handbook 12, London: Blackwell Science 1974
    Search in Google Scholar
  5. Šuput D, Milutinovič A, Serša I, Sedmak B. Chronic exposure to cyanobacterial lyophilizate reveals stronger effects than exposure to pure microcystins - a MRI study. Radiol Oncol 2002; 36: 165-7.
    Search in Google Scholar
  6. Keil C, Forchert A, Fastner J, Szewzyk U, Rotard W, Chorus I, Krätke R. Toxicity and microcystin content of extracts from a Planktothrix bloom and two laboratory strains. Water Res 2002; 36: 2133-9.10.1016/S0043-1354(01)00417-1
    Search in Google Scholar
  7. Žegura B, Sedmak B, Filipič M. Microcystin-LR induces oxidative DNA damage in human hepatoma cell line HepG2. Toxicon 2003; 41: 41-8.10.1016/S0041-0101(02)00207-6
    Search in Google Scholar
  8. Žegura B, Lah TT, Filipič M. The role of reactive oxygen species in microcystin-LR induced DNA damage. Toxicology 2004; 200: 59-68.10.1016/j.tox.2004.03.006
    Search in Google Scholar
  9. Sukenik A, Eshkol R, Livne A, Hadas O, Rom M, Tchernov D, et al. Inhibition of growth and photosynthesis of the dinoflagellate Peridinium gatunense by Microcystis sp. (cyanobacteria): a novel allelopathic mechanism. Limnol Oceanogr 2002; 47: 1656-63.10.4319/lo.2002.47.6.1656
    Search in Google Scholar
  10. Vardi A, Schatz D, Beeri K, Motro U, Sukenik A, Levine A, Kaplan A. Dinoflagellate-cyanobacterium communication may determine the composition of phytoplankton assemblage in a mesotrophic lake. Curr Biol 2002; 12: 1767-72.10.1016/S0960-9822(02)01217-4
    Search in Google Scholar
  11. Sedmak B, Eleršek T. Microcystins induce morphological and physiological changes in selected representative phytoplanktons. Microbial Ecol 2006; 51: 508-15.10.1007/s00248-006-9045-916645927
    Search in Google Scholar
  12. Schatz D, Keren Y, Vardi A, Sukenik A, Carmeli S, Börner T, et al. Towards clarification of the biological role of microcystins, a family of cyanobacterial toxins. Environm Microbiol 2007; 9: 965-70.10.1111/j.1462-2920.2006.01218.x17359268
    Search in Google Scholar
  13. Sedmak B, Kosi G. The role of microcystins in heavy cyanobacterial bloom formation. J Plankton Res 1998; 20: 691-708; 1998; 20: 1421.
    Search in Google Scholar
  14. Sedmak B, Kosi G. Harmful cyanobacterial blooms in Slovenia - Bloom types and microcystin producers. Acta Biol Slovenica 2002; 45: 17-30.
    Search in Google Scholar
  15. Grach-Pogrebinsky O, Sedmak B, Carmeli S. Protease inhibitors from a Slovenian Lake Bled toxic waterbloom of the cyanobacterium Planktothrix rubescens.Tetrahedron 2003; 59: 8329-36.10.1016/j.tet.2003.09.006
    Search in Google Scholar
  16. Sivonen K, Jones G. Cyanobacterial toxins. In Chorus I Bartram J, editors. Toxic cyanobacteria in water, Geneva: World Health Organization, E & FN Spon, 1999: 41-410.
    Search in Google Scholar
  17. Welker M, Brunke M, Preussel K, Lippert I, von Döhren H. Diversity and distribution of Microcystis (Cyanobacteria) oligopeptide chemotypes from natural communities studied by single-colony mass spectrometry. Microbiol 2004; 150: 1785-96.10.1099/mic.0.26947-0
    Search in Google Scholar
  18. Sedmak B, Carmeli S, Eleršek T. >>Non-toxic<< cyclic peptides induce lysis of cyanobacteria - an effective cell population density control mechanism in cyanobacterial blooms. Microb Ecol 2007; DOI 10.1007/s00248-007-9336-9.10.1007/s00248-007-9336-9
    Search in Google Scholar
  19. Starmach K. Cyanophyta - sinice, Glaucophyta - glaucofiti. Flora słodkow. Polski 2. Warszawa: P.W.N.; 1966: 807 pp.
    Search in Google Scholar
  20. Anagnostidis K, Komarek J. Modern approach to the classification system of cyanophytes. 3 - Oscillatoriales. Arch Hydrobiol 1988; Suppl 80: 1-4.
    Search in Google Scholar
  21. Erlendsson LS, Fillippusson H. Purification and characterisation of ovine pancreatic elastase. Comp Biochem Physiol Part B 1998; 120: 549-57.10.1016/S0305-0491(98)10044-5
    Search in Google Scholar
  22. Bieth J, Spiess B, Wermuth CG. The synthesis and analytical use of a highly sensitive and convenient substrate of elastase. Biochem Med 1974; 11: 350-7.10.1016/0006-2944(74)90134-3
    Search in Google Scholar
  23. Dixon M, Webb EC, Thorne CJR, Tipton KF. Enzymes, 3th ed., London: Longman; 1979.
    Search in Google Scholar
  24. Bieth JG. Pathophysiological interpretation of kinetic constants of protease inhibitors. Bull Europ Physiopath Resp 1980; 16: 183-97.
    Search in Google Scholar
  25. Holst-Hansen C, Brünner N. MTT - cell proliferation assay. In: Celis JE, editor. Cell biology: a laboratory handbook, 2nd ed. San Diego: Academic Press; 1998; 16-18.
    Search in Google Scholar
  26. Fujii K Sivonen K, Nakano T Harada K-I. Structural elucidation of cyanobacterial peptides encoded by peptide synthetase gene in Anabaena species. Tetrahedron 2002; 58: 6863-71.10.1016/S0040-4020(02)00747-0
    Search in Google Scholar
  27. Lawton LA, Edwards C. Purification of microcystins. J Chromatogr A 2001; 912: 191-209.10.1016/S0021-9673(01)00592-1
    Search in Google Scholar
  28. Via-Ordorika L, Fastner J, Kurmayer R, Hisbergues M, Dittmann E, Komarek J, et al. Distribution of microcystin-producing and non-microcystin-producing Microcystis sp. in European freshwater bodies: Detection of microcystins and microcystin genes in individual colonies. System Appl Microbiol 2004; 27: 592-602.10.1078/072320204174816315490561
    Search in Google Scholar
  29. Mbedi S, Welker M, Fastner J, Wiedner C. Variability of the microcystin synthetase gene cluster in the genus Planktothrix (Oscillatoriales, Cyanobacteria). FEMS Microbiol Lett 2005; 245: 299-306.10.1016/j.femsle.2005.03.02015837386
    Search in Google Scholar
  30. Kurmayer R, Dittmann E, Fastner J, Chorus I. Diversity of microcystin genes within a population of the toxic cyanobacterium Microcystis spp. In Lake Wannsee (Berkin, Germany). Microbial Ecol 2002; 43: 107-118.10.1007/s00248-001-0039-311984633
    Search in Google Scholar
  31. Kurmayer R, Christiansen G, Fastner J, Börner T. Abundance of active and inactive microcystin genotypes in populations of the toxic cyanobacterium Planktothrix spp. Environ Microbiol 2004; 6: 831-41.10.1111/j.1462-2920.2004.00626.x15250885
    Search in Google Scholar
  32. Scheffer M, Rinaldi S, Gragnani A, Mur LR, Van Nes EH. On the dominance of filamentous cyanobacteria in shallow, turbid lakes. Ecology 1997; 78: 272-82.10.1890/0012-9658(1997)078[0272:OTDOFC]2.0.CO;2
    Search in Google Scholar
  33. Feuillade J. Studies on lake Nantua: The cyanobacterium (blue-green alga) Oscillatoria rubescens DC. Arch Hydrobiol Beih Ergebn Limnol 1994; 41: 77-93.
    Search in Google Scholar
  34. Lindholm T, Meriluoto JAO. Recurrent depth maxima of the hepatotoxic cyanobacterium Oscillatoria agardhii.Can J Fish Aquat Sci 1991; 48: 1629-34.10.1139/f91-193
    Search in Google Scholar
  35. Namikoshi M, Rinehart KL. Bioactive compounds produced by cyanobacteria. J Ind Microbiol 1996; 17: 373-84.10.1007/BF01574768
    Search in Google Scholar
  36. Fastner J, Erhard M, Carmichael WW, Sun F, Rinehart KL, Ronicke H, et al. Characterization and diversity of microcystins in natural blooms and strains of the genera Microcystis and Planktothrix from German freshwaters. Arch Hydrobiol 1999; 145: 147-63.10.1127/archiv-hydrobiol/145/1999/147
    Search in Google Scholar
  37. Grach-Pogrebinsky O, Sedmak B, Carmeli S. Seco[D-Asp3]microcystin-RR and [D-Asp3, D-Glu(OMe)6 microcystin-RR, two new microcystins from a toxic water bloom of the cyanobacterium Planktothrix rubescens.J Nat Prod 2004; 67: 337-42.10.1021/np034036r
    Search in Google Scholar
  38. Barco M, Flores C, Rivera J, Caixach J. Determination of microcystin variants and related peptides present in a water bloom of Planktothrix (Oscillatoria) rubescens in a Spanish drinking water reservoir by LC/ESI-MS. Toxicon 2004; 44: 881-6.10.1016/j.toxicon.2004.08.011
    Search in Google Scholar
  39. Gkelis S, Harjunpaa V, Lanaras T, Sivonen K. Diversity of hepatotoxic microcystins and bioactive anabaenopeptins in cyanobacterial blooms from Greek freshwaters. Env Toxicol 2005; 20: 249-56.10.1002/tox.20105
    Search in Google Scholar
  40. Akcaalan R, Young FM, Metcalf JS, Morrison LF, Albay M, Codd GA. Microcystin analysis in single filaments of Planktothrix spp. in laboratory cultures and environmental blooms. Water Res 2006; 40: 1583-90.10.1016/j.watres.2006.02.020
    Search in Google Scholar
  41. Carmichael WW. The toxins of cyanobacteria. Sci Am 1994; 270: 64-72.10.1038/scientificamerican0194-78
    Search in Google Scholar
  42. Filipič M, Žegura B, Sedmak B, Horvat-Žnidaršič I, Milutinovič A, Šuput D. Subchronic exposure of rats to sublethal dose of microcystin-YR induces DNA damage in multiple organs. Radiol Oncol 2007; 41: 15-22.10.2478/v10019-007-0003-z
    Search in Google Scholar
  43. WHO. Guidelines for Safe Recreational Water Environments, Vol. 1: Coastal and Fresh Waters, Geneva: World Health Organization; 2003.
    Search in Google Scholar
  44. WHO. Guidelines for Drinking-water Quality, 1st addendum to 3rd edition, Recommendations, Geneva: World Health Organization; 2006.
    Search in Google Scholar
  45. Directive 2006/7/EC of the European Parliament and of the Council of 15 February 2006 concerning the management of bathing water quality and repealing Directive 76/160/EEC. Official J EU, L 64: 37-51.
    Search in Google Scholar
  46. Gkelis S, Lanaras T, Sivonen K. The presence of microcystins and other cyanobacterial bioactive peptides in aquatic fauna collected from Greek freshwaters. Aquatic Toxicol 2006; 78: 2-41.10.1016/j.aquatox.2006.02.00116540185
    Search in Google Scholar
DOI: https://doi.org/10.2478/v10019-008-0001-9 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Journal RSS Feed
Language: English
Page range: 102 - 113
Published on: May 10, 2008
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
tumour promoters,
microcystin,
anabaenopeptin,
planktopeptin,
toxic cyanobacterial blooms,
environmental health
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Haematology, oncology,
Radiology

© 2008 Bojan Sedmak, Tina Eleršek, Olga Grach-Pogrebinsky, Shmuel Carmeli, Nataša Sever, Tamara Lah, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons License.

Volume 42 (2008): Issue 2 (June 2008)