Have a personal or library account? Click to login
Ionising radiation and trans-generational instability Cover

Ionising radiation and trans-generational instability

By: Ivana Vrhovac and  Goran Nikšić  
Open Access
|Dec 2007

References

  1. Garaj-Vrhovac V, Kopjar N, Ražem D, Vekić B, Miljanić S, Ranogajec-Komor M. Application of the alkaline comet assay in biodosimetry: assessment of in vivo DNA damage in human peripheral leukocites after γ-radiation incident. Radiat Prot Dosim 2002; 98: 407-16.10.1093/oxfordjournals.rpd.a006731
  2. Neel JV, Schull WJ, Awa AA, Satoh C, Kato H, Otake M, et al. The children of parents exposed to atomic bombs, estimates of the genetic doubling dose of radiation for humans. Am J Hum Genet 1990; 46: 1053-72.
  3. Dubrova YE, Plumb M, Gutierrez B, Boulton E, Jeffreys AJ. Transgenerational mutation by radiation. Nature 2000; 405: 37.10.1038/35011135
  4. Strachan T, Read A. Human Molecular Genetics 2. Oxford: BIOS Scientific Publishers Ltd; 1999.
  5. Sadamoto S, Suzuki S, Kamiya K, Kominami R, Dohi K, Niwa O. Radiation induction of germline mutation at a hypervariable mouse minisatellite locus. Int J Radiat Biol 1994; 65: 549-57.10.1080/09553009414550641
  6. Bois P, Stead JHD, Bakshi S, Williamson J, Neumann R, Moghadaszadeh B, et al. Isolation and characterization of mouse minisatellites. Genomics 1998; 50: 317-30.10.1006/geno.1998.5329
  7. Sankaranarayanan K. Ionizing radiation and genetic risks X. The potential "disease phenotypes" of radiation-induced genetic damage in humans, perspectives from human molecular biology and radiation genetics. Mutat Res 1999; 429: 45-83.
  8. Kodaira M, Satoh C, Hiyama K, Toyama K. Lack of effects of atomic-bomb radiation on genetic instability of tandem-repetitive elements in human germ-cells. Am J Hum Genet 1995; 57: 1275-83.
  9. Dubrova YE, Nesterov VN, Krouchinsky NG, Ostapenko VA, Neumann R, Neil DL, et al. Human minisatellite mutation rate after the Chernobyl accident. Nature 1996; 380: 683-6.10.1038/380683a0
  10. Byrne J, Rasmussen SA, Steinhorn SC, Connelly RR, Myers MH, Lynch CF, et al. Genetic diseases in offspring of long-term survivors of childhood and adolescent cancer. Am J Hum Genet 1998; 62: 45-52.10.1086/301677
  11. Kelly R, Bulfield G, Collick A, Gibbs M, Jeffreys AJ. Characterization of a highly unstable mouse minisatellite locus: Evidence for somatic mutation during early development. Genomics 1989; 17: 121-8.10.1016/0888-7543(89)90126-2
  12. Dubrova YE, Jeffreys AJ, Malashenko AM. Mouse minisatellite mutations induced by ionizing radiation. Nature Genet 1993; 5: 92-4.10.1038/ng0993-92
  13. Sankaranarayanan K, Chakraborty R. Ionizing radiation and genetic risks XI. The doubling dose estimates from the mid- 1950s to present and the conceptual changes to the use of human data on spontaneous mutation rates and mouse data on induced mutation rates for doubling dose calculations. Mutat Res 2000; 453: 107-27.10.1016/S0027-5107(00)00108-1
  14. Vergnaud G, Denoeud F. Minisatellites, mutability and genome architecture. Genome Res 2000; 10: 899-907.10.1101/gr.10.7.89910899139
  15. Little JB. Radiation carcinogenesis. Carcinogenesis 2000; 21: 397-404.10.1093/carcin/21.3.397
  16. Dubrova YE, Plumb M, Brown J, Fennely J, Bois P, Goodhead D, et al. Stage specificity, dose response and doubling dose for mouse minisatellite germline mutation induced by acute radiation. Proc Natl Acad Sci 1998; 95: 6251-5.10.1073/pnas.95.11.6251
  17. Bois PR. Hypermutable minisatellites, a human affair. Genomics 2003; 81: 349-55.10.1016/S0888-7543(03)00021-1
  18. Armour JAL, Brinkworth MH, Kamischke A. Direct analysis by small-pool PCR of MS205 minisatellite mutation rates in sperm after mutagenic therapies. Mutat Res 1999; 445: 73-80.10.1016/S1383-5718(99)00144-8
  19. May CA, Tamaki K, Neumann R, Wilson G, Zagars G, Pollack A, et al. Minisatellite mutation frequency in human sperm following radiotherapy. Mutat Res 2000; 453: 67-75.10.1016/S0027-5107(00)00085-3
  20. Bruce A, Roberts K, Lewis J, Raff M, Walter P, Johnson A. Molecular biology of the cell (4th edition): New York: Garland Pub; 2002.
  21. Fan YJ, Wang Z, Sadamoto S, Ninomiya Y, Kotomura N, Kamiya K, et al. Dose-response of radiation induction of a germline mutation at a hypervariable mouse minisatellite locus. Int J Radait Biol 1995; 68: 177-83.10.1080/095530095145510817658143
  22. Jeffreys AJ, Tamaki K, MacLeod A, Monckton DG, Neil DL, Armour JAL. Complex gene conversion events in germline mutation at human minisatellite. Nature Genet 1994; 6: 136-45.10.1038/ng0294-1368162067
  23. Jeffreys AJ, Neumann R. Somatic mutation process at a human minisatellite. Hum Mol Genet 1997; 6: 129-36.10.1093/hmg/6.1.1299002681
  24. Tamaki K, May CA, Dubrova YE, Jeffreys AJ. Extremly complex repeat shuffling during germline mutation at human minisatellite B6.7. Hum Mol Genet 1999; 8: 879-88.10.1093/hmg/8.5.87910196378
  25. Buard J, Collick AJ, Brown J, Jeffreys AJ. Somatic versus germline mutataion process at minisatellite CEBI (D2S90) in human and transgenic mice. Genomics 2000; 65: 95-103.10.1006/geno.2000.616110783256
  26. Dubrova YE. Transgenerational germline instability. 33th Annual Meeting of the European Environmental Mutagen Society" Aberdeen, Great Britain 2003, Abstract pp 18.
  27. Barber R, Plumb MA, Boulton E, Roux I, Dubrova YE. Elevated mutation rates in the germ line of first- and second-generation offspring of irradiated male mice. Proc Natl Acad Sci USA 2002; 99: 6877-82.10.1073/pnas.10201539912449711997464
  28. Niwa O, Kominami R. Untargeted mutation of the maternally derived mouse hypervariable minisatellite allele in F1 mice born to irradiated spermatozoa. Proc Natl Acad Sci USA 2002; 98: 1705-10.10.1073/pnas.98.4.17052932111172015
  29. Dubrova YE. Monitoring of radiation-induced germline mutation in human. Swiss Medical Weekly 2003; 133: 474-8.10.4414/smw.2003.10228
  30. Dubrova YE, Grant G, Chumal AA, Stezhka VA, Karakasian AN. Elevated minisatellite mutation rate in the post chernobyl families from Ukraine. Am J Hum Genet 2002; 71: 801-9.10.1086/34272937853712226793
  31. Jeffreys N, Weitzel JN, Ding S, Larson GP, Nelson RA, Goodman A, et al. The HRASI minisatellite locus and risk of ovarian cancer. Cancer Res 2000; 60: 259-61.
  32. Gardner MJ, Snee MP, Hall AJ, Powell CA, Downes S, Terrell JD. Results of case-control study of leukaemia and lymphoma among young people near Sellefield nuclear plant in West Cumbria. Br Med J 1990; 300: 423-9.10.1136/bmj.300.6722.42316622592107892
  33. Wells RD, Dere R, Hebert ML, Napierala M, Son LS. Advance in mechanisms of genetic instability related to hereditary neurological diseases. Nucl Acids Res 2005; 33: 3785-798.10.1093/nar/gki697117491016006624
DOI: https://doi.org/10.2478/v10019-007-0021-x | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 123 - 132
Published on: Dec 6, 2007
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2007 Ivana Vrhovac, Goran Nikšić, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons License.

Volume 41 (2007): Issue 3 (September 2007)