Dosimetry of two new interstitial brachytherapy sources

Saidi, Pooneh; Sadeghi, Mahdi

doi:10.2478/v10013-011-0013-4

Abstract

With increased demand for low ¹⁰³Pd (palladium) seed sources, to treat prostate and eye cancers, new sources have been designed and introduced. This article presents the two new palladium brachytherapy sources, IR03-¹⁰³Pd and IR04-¹⁰³Pd that have been developed at Nuclear Science and Technology Research Institute. The dosimetry parameters such as the dose rate constant Λ, the radial dose function g(r), and the anisotropy function F(r,θ), around the sources have been characterized using Version 5 Monte Carlo radiation transport code in accordance with the update AAPM Task Group No. 43 report (TG-43U1). The results indicated the dose rate constant of 0.689±0.02 and 0.667±0.02 cGy h^-1 U^-1 for the IR03-¹⁰³Pd and IR04-¹⁰³Pd sources respectively, which are in acceptable agreement with other commercial seeds. The calculated results were compared with published results for those of other source manufacturers. However, they show an acceptable dose distribution, using for clinical applications is pending experimental dosimetry.

References

Cross section Evaluation Working Group, "ENDF/B-VI Summary documentation (ENDF-201)", Brookhaven National Laboratory Report No. BNL.NCS-17541, 8th ed., National Nuclear Data Center, (December 2000).
Search in Google Scholar
Gearheart DM, Drogin A, Sowards K, Meigooni AS, Ibbott GS. Dosimetric characteristics of a new ¹²⁵I brachytherapy source. Med Phys. 2000; 27: 2278-2285.10.1118/1.129048611099194
Search in Google Scholar
http://www.nea.fr/abs/html/ccc-0740.html
Search in Google Scholar
Kouwenhoven E, Laarse R, Schaart DR. Variation in interpretation of the AAPM TG-43 geometry factor leads to unclearness in brachytherapy dosimetry. Med Phys 2001; 28: 1965-1966.10.1118/1.139856311585228
Search in Google Scholar
Li Z, Palta JR, Fan JJ. Monte Carlo calculations and experimental measurements of dosimetry parameters of a new ¹⁰³Pd source. Med Phys. 2000; 27: 1108-1112.10.1118/1.59897510841416
Search in Google Scholar
Li Z. Monte Carlo calculation of dosimetry parameters of the Urcor Prostaseed ¹²⁵I source. Med Phys. 2000; 29: 2278-2285.
Search in Google Scholar
Meigooni AS, Bharucha Z, Yoe-Sein M, Sowards K. Dosimetric characteristic of the best double -wall ¹⁰³Pd brachytherapy source. Med Phys. 2001; 28: 2568-2575.10.1118/1.141400711797962
Search in Google Scholar
Melhus CS, Rivard MJ. COMS eye plaque brachytherapy dosimetry simulations for ¹⁰³Pd, ¹²⁵I, and ¹³¹Cs. Med Phys. 2008; 35: 3364-3371.10.1118/1.294060428513032
Search in Google Scholar
Monte Carlo Team, MCNP-A General Monte Carlo N-Particle Transport Code - Version 5, Los Alamos National Laboratory http://mcnp-green.lanl.gov/index.html
Search in Google Scholar
Murali V, Kurup PGG, Mahadev P, Mahalakshmi S. Dosimetric analysis and comparison of IMRT and HDR brachytherapy in treatment of localized prostate cancer. J Med Phys. 2010; 35: 113-119.10.4103/0971-6203.62201288430320589121
Search in Google Scholar
Nath R, Anderson LL, Luxton G, Weaver KA, Williamson JF, Meigooni AS. Dosimetry of interstitial brachytherapy sources: recommendations of the AAPM Radiation Therapy Committee Task Group No.43. American Association of Physicists in Medicine. Med Phys. 1995; 22: 209-234.10.1118/1.5974587565352
Search in Google Scholar
Nath R, Yue N, Shahnazi K, Bongiorni PJ. Measurement of dose-rate constant for ¹⁰³Pd seeds with air-kerma strength calibration based upon a primary national standard. Med Phys. 2000; 27: 655-658.10.1118/1.59892510798685
Search in Google Scholar
Popescu CC, Wise J, Sowards K, Meigooni AS, Ibbott GS. Dosimetric characteristic of the Pharma Seed model BT-125-I source. Med Phys. 2000; 27: 2174-2181.10.1118/1.128989711011748
Search in Google Scholar
Raisali Gh, Ghonchehnazi MG, Shokrani P, Sadeghi M. Monte Carlo and experimental characterization of the first AMIRS ¹⁰³Pd brachytherapy. Appl Radiat Isot. 2008: 66: 1856-1860.10.1016/j.apradiso.2008.06.00718657981
Search in Google Scholar
Rivard MJ, Coursey BM, DeWerd LA, Hanson WF, Huq MS, Ibbott GS, Mitch MG, Nath R, Williamson JF. Update of AAPM Task Group No. 43 Report: A revised AAPM protocol for brachytherapy dose calculations. Med Phys. 2004; 31: 633-674.10.1118/1.164604015070264
Search in Google Scholar
Rivard MJ. Monte Carlo calculation of AAPM Task Group Report No.43 dosimetry parameters for the MED3631-A/M ¹²⁵I source. Med Phys. 2001; 28: 629-637.10.1118/1.135530611339761
Search in Google Scholar
Sadeghi M, Hosseini SH, Raisali Gh. Experimental measurements and Monte Carlo calculations of dosimetric parameters of the IRA1-¹⁰³Pd brachytherapy source. Appl Radiat Isot 2008; 66: 1431-1437.10.1016/j.apradiso.2008.02.08118387806
Search in Google Scholar
Sadeghi M, Raisali Gh, Hosseini SH, Shahvar A. Monte Carlo calculations and experimental measurements of dosimetric parameters of the IRA-103Pd brachytherapy source. Med Phys. 2008; 35: 1288-1294.10.1118/1.287022918491522
Search in Google Scholar
Saidi P, Sadeghi M, Shirazi A, Tenreiro C. Monte Carlo calculation of dosimetry parameters for the IR08-103Pd brachytherapy source. Med Phys. 2010; 37: 2509-2515.10.1118/1.341692220632562
Search in Google Scholar
Wallace RE, Fan JJ. Dosimetric characterization of a new design 103-palladium brachytherapy source. Med Phys. 1999; 26: 2465-2470.10.1118/1.59876510587234
Search in Google Scholar
Williamson JF. Monte Carlo modeling of the transverse-axis dose distribution of the model 200 ¹⁰³Pd interstitial brachytherapy source. Med Phys. 2000; 27: 643-654.10.1118/1.59892410798684
Search in Google Scholar
Zhang H, Martin D, Chiu-Tsao S, Meigooni A, Thomadsen B. A comprehensive dosimetric between ¹³¹Cs and ¹²⁵I brachytherapy sources for COMS eye plaque implant. Brachytherapy 2010; 9: 362-372.10.1016/j.brachy.2009.07.00720116342
Search in Google Scholar

Dosimetry of two new interstitial brachytherapy sources

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