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An in vitro and in vivo comparative study of directly compressed solid dispersions and freeze dried sildenafil citrate sublingual tablets for management of pulmonary arterial hypertension Cover

An in vitro and in vivo comparative study of directly compressed solid dispersions and freeze dried sildenafil citrate sublingual tablets for management of pulmonary arterial hypertension

Acta Pharmaceutica
Volume 62 (2012): Issue 3 (September 2012)
By: ,  ,   and    
Open Access
|Nov 2012
References

References

  1. 1. C. W. Oakley, Primary pulmonary hypertension. Case series from the United Kingdom,.(1994) 29S-32S; DOI: 10.1378/chest.105.2_Supplement.29S.
    Open DOISearch in Google Scholar
  2. 2. B. G. Schwartz, L. A. Levine, G. Comstock, V. J. Stecher and R. A. Kloner, Cardiac uses of Phosphodiesterase-5 Inhibitors,(2012) 9-15; DOI:10.1016/j.jacc.2011.07.051.
    Open DOISearch in Google Scholar
  3. 3. G. D. Lewis, R. Shah, K. Shahzad, J. M. Camuso, P. P. Pappagianopoulos, J. Hung, A. Tawakol, R. E. Gerszten, D. M. Systrom, K. D. Bloch, M. J. Semigran, Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension,(2007) 1555-1562; DOI: 10.1161/CIRCULATIONAHA.107.716373.
    Open DOISearch in Google Scholar
  4. 4. V. Q. Chau, F. N. Salloum, N. N. Hoke, A. Abbate and R. C. Kukreja, Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathway,(2011) H2272-H2279; DOI: 10.1152/ajpheart.00654.2010.
    Open DOISearch in Google Scholar
  5. 5. J. Nagendran, S. L. Archer, D. Soliman, V. Gurtu, R. Moudgil, A. Haromy, C. St Aubin, L. Webster, I. M. Rebeyka, D. B. Ross, P. E. Light, J. R. Dyck, E. D. Michelakis, Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility,(2007) 238-248; DOI: 10.1161/CIRCULATIONAHA. 106.655266.
    Search in Google Scholar
  6. 6. L. Zhao, N. A. Mason, N. W. Morrell, B. Kojonazarov, A. Sadykov, A. Maripov, M. M. Mirrakhimov, A. Aldashev and M. R. Wilkins, Sildenafil inhibits hypoxia-induced pulmonary hypertension,(2001) 424-428; DOI: 10.1161/hc2901.093117.
    Open DOISearch in Google Scholar
  7. 7. P. Rajagopalan, A. Mazzu, C. Xia, R. Dawkins and P. Sundaresan, Effect of high-fat breakfast and moderate-fat evening meal on pharmacokinetics of vardenafil, an oral phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction,(2003) 260-267; DOI: 10.1177/0091270002250604.
    Open DOISearch in Google Scholar
  8. 8. A. H. Elshafeey, E. R. Bendasand O. H. Mohamed, Intranasal microemulsion of sildenafil citrate:evaluation andpharmacokinetic study in rabbits,.(2009) 361-367; DOI: 10.1208/s12249-009-9213-6.
    Open DOISearch in Google Scholar
  9. 9. A. H. Shajaei, Buccal mucosa as a route for systemic drug delivery.(1998) 15-30; http://www.ualberta.ca/~csps/JPPS1(1)/A.Shojaei/buccalreview.htm.
    Search in Google Scholar
  10. 10. Z. Bayrak, C. Tas, U. Tasdemir, H. Erol, C. K. Ozkan, A. Sayaser and Y. Ozkan, Formulation of zolmitriptan sublingual tablets prepared by direct compression with different polymers:andevaluation,(2011) 499-505; DOI: 10.1016/j.ejpb.2011.02.014.
    Open DOISearch in Google Scholar
  11. 11. S. A. Randale, C. S. Dabhi, A. R. Tekade, V. S. Belgamwar, S. G. Gattani and S. J. Surana, Rapidly disintegrating tablets containing taste masked metoclopramide hydrochloride prepared by extrusion-precipitation method,,(2010) 443-448; DOI: 10.1248/cpb.58.443.
    Open DOISearch in Google Scholar
  12. 12. S. Bandari, R. K. Mittapalli, R.Gannu and Y. H. Rao, Orodispersibletablets: an overview,.(2008) 2-11; DOI: 10.4103/0973-8398.41557.
    Open DOISearch in Google Scholar
  13. 13. G. Abdelbary, C. Eouani, P. Prinderre, J. Joachim, J. Reynier and P. Piccerelle, Determination of thedisintegration profile of rapidly disintegrating tablets and correlation with oral disintegration,.(2005) 29-41; DOI:10.1016/j.ijpharm.2004.08.019.
    Open DOISearch in Google Scholar
  14. 14. J. W. Moore and H. H. Flanner, Mathematical comparison of dissolution profiles,,(1996) 64-74.
    Search in Google Scholar
  15. 15. »Declaration of Helsinki.« As amended by the 59th World Medical Assembly (WMA). World Medical Association, Seoul, South Korea, October 2008. Available at: http://www.wma.net/e/ethicsunit/helsinki.htm.
    Search in Google Scholar
  16. 16. V. P. Shah, K. K. Midha, S. Dighe, I. J. McGilveray, J. P. Skelly, A. Yacobi, T. Layloff, C. T. Viswanathan, C. E. Cook and R. D. McDowall, Analytical methods validation: bioavailability, bioequivalence and pharmacokinetic studies. Conference report,(1991) 249-255; DOI: 10.1002/jps.2600810324.
    Open DOISearch in Google Scholar
  17. 17. A. P. Simonelli, S. C. Mehta, W. I. Higuchi. Dissolution rates of high energy polyvinylpyrrolidone-sulfathiazole coprecipitates,(1969) 538-549; DOI: 10.1002/jps.2600580503.
    Open DOISearch in Google Scholar
  18. 18. O. I. Corrigan, Mechanisms of dissolution of fast release solid dispersions.(1985) 697-724; DOI: 10.3109/03639048509056896.
    Open DOISearch in Google Scholar
  19. 19. M. Newa, K. H. Bhandari, D. X. Li, T. H. Kwon, J. A. Kim, B. K. Yoo, J. S. Woo, W. S. Lyoo, C. S. Yong, H. G. Choi, Preparation, characterization andevaluation of ibuprofen binary solid dispersions with Poloxamer 188,(2007) 228-237; DOI: 10.1016/j.ijpharm.2007. 05.031.
    Search in Google Scholar
  20. 20. N. Passerini, M. L. Gonzalez-Rodriguez, C. Cavallari, L. Rodriguez and B. Albertini, Preparation and characterisation of ibuprofen-poloxamer 188 granules obtained by melt granulation,(2002) 71-78; DOI: 10.1016/S0928-0987(01)00210-X.
    Open DOISearch in Google Scholar
  21. 21. P. P. Shah and R. C. Mashru, Development and evaluation of artemether taste masked rapid disintegrating tablets with improved dissolution using solid dispersion technique.
    Search in Google Scholar
  22. (2008) 494-500; DOI: 10.1208/s12249-008-9066-4. 22. S. Khan, H. Batchelor, P. Hanson, Y. Perrie and A. R. Mohammed, Physicochemical characterization, drug polymer dissolution andevaluation of phenacetin and phenylbutazone solid dispersions with polyethylene glycol 8000,(2011) 4281-4294; DOI: 10.1002/jps.22613.
    Open DOISearch in Google Scholar
  23. 23. A. Quadir and K. Kolter, A comparative study of current superdisintegrants,2006
    Search in Google Scholar
  24. 24. R. Chandrasekhar, Z. Hassan, F. Alhusban, A. M. Smith and A. R. Mohammed, The role of formulation excipients in the development of lyophilized fast-disintegrating tablets,(2009) 119-129; DOI: 10.1016/j.ejpb.2008.11.011.
    Open DOISearch in Google Scholar
  25. 25. W. L. Chiou and S. Riegelman, Pharmaceutical application of solid dispersion system,(1971) 1281-1302; DOI: 10.1002/jps.2600600902.
    Open DOISearch in Google Scholar
  26. 26. R. A. Shoukri, I. S. Ahmed and R. N. Shamma,andevaluation of nimesulide lyophilized orally disintegrating tablets,(2009) 162-171; DOI: 10.1016/j.ejpb.2009.04.005.
    Open DOISearch in Google Scholar
  27. 27. V. B. Djagny, Z. Wang and S. Xu, Gelatin: A valuable protein for food and pharmaceutical industries: Review,(2001) 481-492; DOI: 10.1080/20014091091904.
    Open DOISearch in Google Scholar
  28. 28. P. J. Dawson and D. J. Hockley, Scanning electron microscopy of freeze-dried preparations: relationship of morphology to freeze-drying parameters,(1991) 185-192.
    Search in Google Scholar
  29. 29. D. J. van Drooge, W. L. J. Hinrichs and H. W. Frijlink, Incorporation of lipophilic drugs in sugar glasses by lyophilization using a mixture of water and tertiary butyl alcohol as solvent,(2004) 713-725; DOI: 10.1002/jps.10590.
    Open DOISearch in Google Scholar
  30. 30. A. A. Mahmoud and S. Salah, Fast relief from migraine attacks using fast-disintegrating sublingual zolmitriptan tablets,(2011) 1-8; DOI:10.3109/03639045.2011.625949.
    Open DOISearch in Google Scholar
  31. 31. REVATIO - sildenafil citrate tablet, film coatedPfizer Labs http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfmfiarchiveid=10206.
    Search in Google Scholar
  32. 32. A. Abdelbary, A. H. Elshafeeyand G. Zidan, Comparative effects of different cellulosic-based directly compressed orodispersable tablets on oral bioavailability of famotidine, Carb(2009) 799-806; DOI:10.1016/j.carbpol.2009.02.030.
    Open DOISearch in Google Scholar
  33. 33. M. M. Rawas-Qalaji, F. E. Simons and K. J.Simons, Sublingual epinephrine tablets versus intramuscular injection of epinephrine: Dose equivalence for potential treatment of anaphylaxis,(2006) 398-403; DOI:10.1016/j.jaci.2005.12.1310.
    Open DOISearch in Google Scholar
  34. 34. G. V. Betageri and K. R. Makarla, Enhancement of dissolution of glyburide by solid dispersion and lyophilization techniques,(1995) 155-160; DOI: 10.1016/0378-5173(95) 04114-1.
    Search in Google Scholar
DOI: https://doi.org/10.2478/v10007-012-0027-9 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English, Croatian, Slovenian
Page range: 411 - 432
Published on: Nov 6, 2012
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Keywords:
sildinafil,
orodispersable sublingual tablets,
pulmonary arterial hypertension,
poloxamer 188,
solid dispersions,
direct compression,
freeze drying
Related subjects:
Pharmacy,
Pharmacy, other

© 2012 Reham Zayed, Amany O. Kamel, Marwa Shukr, Abd El-Hamid El-Shamy, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

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