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Development and characterization of thermosensitive pluronic-based metronidazole in situ gelling formulations for vaginal application Cover

Development and characterization of thermosensitive pluronic-based metronidazole in situ gelling formulations for vaginal application

Acta Pharmaceutica
Volume 62 (2012): Issue 1 (March 2012)
By: ,  ,  ,  ,   and    
Open Access
|Apr 2012
References

References

  1. J. Y. Chang, Y.-K. Oh, H. G. Choi, Y. B. Kim and C.-K. Kim, Rheological evaluation of thermosensitive and mucoadhesive vaginal gels in physiological conditions,(2002) 155-163; DOI: 10.1016/S0378-5173(02)00232-6.
    Open DOISearch in Google Scholar
  2. Y. Qiu and K. Park, Environment-sensitive hydrogels for drug delivery,(2001) 321-339; DOI: 10.1016/S0169-409X(01)00203-4.
    Open DOISearch in Google Scholar
  3. C. K. Mauck, D. Katz, E. P. Sandefer, M. D. Nasution, M. Henderson, G. A. Digenis, I. Su, R. Page and K. Barnhart, Vaginal distribution of Replens and K-Y jelly using three imaging techniques,(2008) 195-204; DOI: 10.1016/j.contraception.2007.11.016.
    Open DOISearch in Google Scholar
  4. I. R. Schmolka, Artificial skin. I. Preparation and properties of pluronic F-127 gels for the treatment of burns,(1972) 571-582; DOI: 10.1002/jbm.820060609.
    Open DOISearch in Google Scholar
  5. H. G. Choi, J. H. Jung, J. M. Ryu, S. J. Yoon, Y. K. Oh and C. K. Kim, Development of in situ-gelling and mucoadhesive acetaminophen liquid suppository,(1998) 33-44; DOI: 10.1016/S0378-5173(97)00386-4.
    Open DOISearch in Google Scholar
  6. A. A. Koffi, F. Agnely, G. Ponchel and J. L. Grossiord, Modulation of the rheological and mucoadhesive properties of thermosensitive poloxamer based hydrogels intended for the rectal administration of quinine,(2006) 328-335; DOI: 10.1016/j.ejps.2005.11.001.
    Open DOISearch in Google Scholar
  7. H. S. Ch'ng, H. Park, P. Kelly and J. R. Robinson, Bioadhesive polymers as platforms for oral controlled drug delivery. II. Synthesis and evaluation of some swelling water insoluble bioadhesive polymers,(1985) 339-405.
    Search in Google Scholar
  8. D. Woolfson, M. L. Umrethia, V. L. Kett and R. K. Malcolm, Freeze-dried, mucoadhesive system for vaginal delivery of the HIV microbicide, dapivirine: Optimisation by an artificial neural network,(2010); DOI: 10.1016/j.ijpharm.2009.12.042.
    Open DOISearch in Google Scholar
  9. A. D. Woolfson, M. L. Umrethia, V. L. Kett and R. K. Malcolm, Freeze-dried, mucoadhesive system for vaginal delivery of the HIV microbicide, dapivirine: Optimisation by an artificial neural network,(2010)136.143; DOI: 10.1016/j.ijpharm.2009.12.042.
    Open DOISearch in Google Scholar
  10. J. Y. Chang, Y.-K. Oh, H. S. Kong, E. J. Kim, D. D. Jang, K. T. Nam and C.-K. Kin, Prolonged antifungal effects of clotrimazole-containing mucoadhesive thermosensitive gels on vaginitis,(2002) 39-50; DOI: 10.1016/S0168-3659(02)00086-X.
    Open DOISearch in Google Scholar
  11. E. Y. Kim, Z. G. Gao, J. S. Park, H. Li and K. Han, rhEGF/HP-β-CD complex in poloxamer gel for ophthalmic delivery,(2002) 159-167; DOI: 10.1016/S0378-5173(01)00933-4.
    Open DOISearch in Google Scholar
  12. A. L. Rashad, W. L. Toffler, N. Wolf, K. Thoraburg, E. P. Kirk, G. Ellis and W. E. Whitehead, Vaginal P02 in healthy women and in women infected with Trichomoniasis vaginalis: Potential implications for metronidazole therapy,(1992) 620-624.
    Open DOISearch in Google Scholar
  13. K. Edsman, J. Carlfors and R. Petersson, Rheological evaluation of poloxamer as an in situ gel for ophthalmic use,(1998) 105-112; DOI: 10.1016/S0928-0987(97)00075-4.
    Open DOISearch in Google Scholar
  14. H. Qi, L. Li, C. Huang, W. Li and C. Wu, Optimization and physicochemical characterization of thermosensitive poloxamer gel containing puerarin for ophthalmic use,(2006) 1500-1507; DOI 10.1248/cpb.54.1500.
    Open DOISearch in Google Scholar
  15. A. Cabana, A. Ait-Kadi and J. Juhasz, Study of the gelation process of polyethylene oxide-poly-propylene oxide-polyethylene oxide copolymer (poloxamer 407) aqueous solutions,(1997) 307-312; DOI: 10.1006/jcis.1997.4880.
    Open DOISearch in Google Scholar
  16. N. Jain, V. Aswal, P. Goyal and P. Bahadur, Micellar structure of an ethylene oxide-propylene oxide block copolymer: a small-angle neutron scattering study,(1998) 8452-8460; DOI: 10.1021/jp982568o.
    Open DOISearch in Google Scholar
  17. I. R. Schmolka, A review of block polymer surfactants,(1977) 110-116; DOI: 10.1007/BF02894385.
    Open DOISearch in Google Scholar
  18. C. Charrueau, C. Tuleu, V. Astre, J.-L. Grossiord and J.-L. Chaumeil, Poloxamer 407 as a thermogelling and adhesive polymer for rectal administration of short-chain fatty acids,(2001) 351-357; DOI: 10.1081/DDC-100103735.
    Open DOISearch in Google Scholar
  19. P. Alexandridis and T. A. Hatton, Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer surfactants in aqueous solutions and at interfaces: thermodynamic, structure, dynamic and modeling,(1995) 1-46; DOI: 10.1016/0927-7757(94)03028-X.
    Open DOISearch in Google Scholar
  20. O. M. Shaaban, G. N. Fetih, N. H. Abdellah, S. Ismail, M. A. Ibrahim and S. A. Ibrahim, A pilot randomized trial for treatment of bacterial vaginosis using in-situ forming metronidazole vaginal gel,(2011) 874-881; DOI: 10.1111/j.1447-0756.2010.01457.x.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/v10007-012-0009-y | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English, Croatian, Slovenian
Page range: 59 - 70
Published on: Apr 3, 2012
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Keywords:
metronidazole,
in situ gelling,
mucoadhesion,
pluronics
Related subjects:
Pharmacy,
Pharmacy, other

© 2012 El-Sayed Ibrahim, Sayed Ismail, Gihan Fetih, Omar Shaaban, Khaled Hassanein, Noura Abdellah, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

Volume 62 (2012): Issue 1 (March 2012)
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