Skip to main content
Have a personal or library account? Click to login
Synthesis, in vitro anticancer screening and radiosensitizing evaluation of some new 4-[3-(substituted)thioureido]-N-(quinoxalin-2-yl)-benzenesulfonamide derivatives Cover

Synthesis, in vitro anticancer screening and radiosensitizing evaluation of some new 4-[3-(substituted)thioureido]-N-(quinoxalin-2-yl)-benzenesulfonamide derivatives

Acta Pharmaceutica
Volume 61 (2011): Issue 4 (December 2011)
By: ,  ,  ,   and    
Open Access
|Dec 2011
References

References

  1. V. K. Tandon, D. B. Yadav, H. K. Maurya, A. K. Chaturvedi and P. K. Shukla, Design, synthesis, and biological evaluation of 1,2,3-trisubstituted-1,4-dihydrobenzo[]quinoxaline-5,10-diones and related compounds as antifungal and antibacterial agents,(2006) 6120-6126; DOI: 10.1016/j.bmc.2006.04.029.
    Open DOISearch in Google Scholar
  2. S. Sehlstedt, P. Aich, J. Bergman, H. Vallberg, B. Nordén and A. Gräslund, Interactions of the antiviral quinoxaline derivative 9-OH-B220 {2,3-dimethyl-6-(dimethylaminoethyl)-9-hydroxy--indolo-[2,3-]quinoxaline} with duplex and triplex forms of synthetic DNA and RNA,(1998) 31-56; DOI: 10.1006/jmbi.1998.1670.
    Open DOISearch in Google Scholar
  3. A. Carta, M. Loriga, G. Paglietti, A. Mattana, P. L. Fiori, P. Mollicotti, L. Mollicotti and S. Zanetti, Synthesis, anti-mycobacterial, anti-trichomonas and anti-candida in vitro activities of 2-substituted-6,7-difluoro-3-methylquinoxaline 1,4-dioxides,(2004) 195-203; DOI: 10.1016/j.ejmech.2003.11.008.
    Open DOISearch in Google Scholar
  4. M. H. Fisher, A. Lusi and J. R. Egerton, Anthelmintic dihydroquinoxalino[2,3-]quinoxalines,(1997) 1349-1352; DOI: 10.1002/jps.2600660942.
    Open DOISearch in Google Scholar
  5. A. Budakoti, A. R. Bhat and A. Azam, Synthesis of new 2-(5-substituted-3-phenyl-2-pyrazolinyl)-1,3-thiazolino[5,4-]quinoxaline derivatives and evaluation of their antiamoebic activity,(2009) 1317-1325; DOI: 10.1016/j.ejmech.2008.02.002.
    Open DOISearch in Google Scholar
  6. R. S. Giri, H. M. Thaker, T. Giordano, J. Williams, D. Rogers, V. Sudersanam and K. K. Vasu, Design, synthesis and characterization of novel 2-(2,4-disubstituted-thiazole-5-yl)-3-aryl-3H-quinazoline-4-one derivatives as inhibitors of NF-κB and AP-1 mediated transcription activation and as potential anti-inflammatory agents,(2009) 2184-2189; DOI: 10.1016/j.ejmech.2008.10.031.
    Open DOISearch in Google Scholar
  7. J. S. Fisherman, B. L. Osborn and H. G. Chun, Chloroquinoxaline sulfonamide: A sulfanilamide antitumor agent entering clinical trials,(1993) 1-9; DOI: 10.1007/BF00873904.
    Open DOISearch in Google Scholar
  8. F. Mohamadi, M. M. Spees and G. B. Grindey, Sulfonylureas: A new class of cancer chemotherapeutic agents,(1992) 3012-3016; DOI: 10.1021/jm00094a013.
    Open DOISearch in Google Scholar
  9. G. F. Rush, S. Rinzel, G. Boder, R. A. Heim, J. E. Toth and G. D. Ponsler, Effects of diarylsulfonylurea antitumor agents on the function of mitochondria isolated from rat liver and GC3/c1 cells,(1992) 2387-2394; DOI: 10.1016/0006-2952(92)90684-B.
    Open DOISearch in Google Scholar
  10. M. M. Ghorab, F. A. Ragab, H. I. Heiba, R. K. Arafa and E. M. El-Hossary,anticancer screening and radiosensitizing evaluation of some new quinolines and pyrimido[4,5-b]quinolines bearing a sulfonamide moiety,(2010) 3677-3684; DOI: 10.1016/j.ejmech.2010.05.014.
    Open DOISearch in Google Scholar
  11. M. M. Ghorab, F. A. Ragab and M. M. Hamed, Design, synthesis and anticancer evaluation of novel tetrahydroquinoline derivatives containing sulfonamide moiety,(2009) 4211-4217; DOI: 10.1016/j.ejmech.2009.05.017.
    Open DOISearch in Google Scholar
  12. M. M. Ghorab, F. A. Ragab, S. I. Alquasoumi, A. M. Alafeefy and S. A. Aboulmagd, Synthesis of some new pyrazolo[3,4-]pyrimidine derivatives of expected anticancer and radioprotective activity,(2010) 171-178; DOI: 10.1016/j.ejmech.2009.09.039.
    Open DOISearch in Google Scholar
  13. P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J. T. Warren, H. Bokesch, S. Kenny and M. R. Boyd, New colorimetric cytotoxicity assay for anticancer-drug screening,(1990) 1107-1112; DOI: 10.1093/jnci/82.13.1107.
    Open DOISearch in Google Scholar
  14. M. S. A. El-Gaby, A. M. Hussein, F. A. M. Abu-Shanab and M. A. M. Abdel Raheim, some hitherto unknown thiosemicarbazide, thiourea, bisthiourea, benzoazole derivatives bearing quinoxalin-2-yl moiety and evaluate their biological activity,(2003) 358-369; DOI: 2780.35400011978567.0050.
    Search in Google Scholar
  15. Y. Nishimura, Rationale for chemoradiotherapy,(2004) 414-420; DOI: 10.1007/s10147-004-0443-z.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/v10007-011-0040-4 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Journal RSS Feed
Language: English, Croatian
Page range: 415 - 425
Published on: Dec 25, 2011
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Keywords:
quinoxaline,
sulfonamides,
anticancer activity,
radiosensitizing effect
Related subjects:
Pharmacy,
Pharmacy, other

© 2011 Mostafa Ghorab, Fatma Ragab, Helmy Heiba, Marwa El-Gazzar, Mostafa El-Gazzar, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

Volume 61 (2011): Issue 4 (December 2011)
Previous article
Next article