Synthesis, antibacterial and potential anti-HIV activity of some novel imidazole analogs

Swastika Ganguly; Vatsal Vithlani; Anup Kesharwani; Ritu Kuhu; Lakshmanan Baskar; Papiya Mitramazumder; Ashok Sharon; Abhimanyu Dev

doi:10.2478/v10007-011-0018-2

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Synthesis, antibacterial and potential anti-HIV activity of some novel imidazole analogs

Acta Pharmaceutica

Volume 61 (2011): Issue 2 (June 2011)

By: Swastika Ganguly, Vatsal Vithlani, Anup Kesharwani, Ritu Kuhu, Lakshmanan Baskar, Papiya Mitramazumder, Ashok Sharon and Abhimanyu Dev

Open Access

|Jun 2011

Abstract

A series of 1-(2-methyl-4-nitro-imidazol-1-yl)-3-arylaminopropan-2-ones (2a-e), 2-methyl-5-nitro-1-{2-[arylmethoxy] ethyl}-1H-imidazoles (5a-d), and N-(3-hydroxyphenyl)-2-(substituted imidazol-1-yl)alkanamides (8a-e) were synthesized with the aim to develop novel imidazole analogs with broad-spectrum chemotherapeutic properties. Title compounds were evaluated for their anti-HIV and antibacterial activities.

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Articles in this issue

DOI: https://doi.org/10.2478/v10007-011-0018-2 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075

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Language: English

Page range: 187 - 201

Published on: Jun 17, 2011

Published by: Croatian Pharmaceutical Society

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

imidazole,

reverse transcriptase,

non-nucleoside reverse transcriptase,

Related subjects:

© 2011 Swastika Ganguly, Vatsal Vithlani, Anup Kesharwani, Ritu Kuhu, Lakshmanan Baskar, Papiya Mitramazumder, Ashok Sharon, Abhimanyu Dev, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

Volume 61 (2011): Issue 2 (June 2011)