Antimicrobial activity of some synthesized glucopyranosyl-pyrimidine carbonitrile and fused pyrimidine systems

Hayam Sayed; Hebat-Allah Abbas; Eman Morsi; Abd Amr; Nayera Abdelwahad

doi:10.2478/v10007-010-0033-8

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Antimicrobial activity of some synthesized glucopyranosyl-pyrimidine carbonitrile and fused pyrimidine systems

Acta Pharmaceutica

Volume 60 (2010): Issue 4 (December 2010)

By: Hayam Sayed, Hebat-Allah Abbas, Eman Morsi, Abd Amr and Nayera Abdelwahad

Open Access

|Dec 2010

Abstract

3-Amino-5-(4-chlorophenylamino)-4-cyanofuran-2-carboxamide (2) was used as the key molecule for preparation of various furopyrimidines 3-9 and formation of spiro-cycloalkane furopyrimidines 10, 11. Also, poly fused heterocyclic compounds 13-17 were prepared from compound 2. The synthesized compounds were screened for their antimicrobial activity.

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Articles in this issue

DOI: https://doi.org/10.2478/v10007-010-0033-8 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075

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Language: English

Page range: 479 - 491

Published on: Dec 17, 2010

Published by: Croatian Pharmaceutical Society

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

pyrimidine,

glucopyranosyl-pyrimidine,

oxazine,

antimicrobial activity

Related subjects:

Pharmacy,

Pharmacy, other

© 2010 Hayam Sayed, Hebat-Allah Abbas, Eman Morsi, Abd Amr, Nayera Abdelwahad, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

Volume 60 (2010): Issue 4 (December 2010)