Skip to main content
Have a personal or library account? Click to login
In vitro antitumor and antiviral activities of new benzothiazole and 1,3,4-oxadiazole-2-thione derivatives Cover

In vitro antitumor and antiviral activities of new benzothiazole and 1,3,4-oxadiazole-2-thione derivatives

Acta Pharmaceutica
Volume 58 (2008): Issue 2 (June 2008)
By: ,  ,  ,   and    
Open Access
|May 2008
References

References

  1. I. Caleta, M. Grdisa, D. Mrvos-Sermek, M. Cetina, V. K. Tralić-Kulenović, G. Pavelić and G. Karminski-Zamola, Synthesis, crystal structure and antiproliferative evaluation of some new substituted benzothiazoles and styrylbenzothiazoles,59 (2004) 297-305; DOI: 10.1016/j.farmac.2004.01.008.
    Open DOISearch in Google Scholar
  2. A. I. Loaiza-Péez, V. Trapni, V. Patel, C. Hose, S. S. Singh, J. B. Trepel, M. F. G. Stevens, T. D. Bradshaw and E. A. Sauville, The aryl hydrocarbons receptor mediates sensitivity of MCF-7 breast cancer cells to the antitumor agent 2-(4-amino-3-methylphenyl) benzothiazole,61 (2002) 13-19.
    Open DOISearch in Google Scholar
  3. V. Trapani, V. Patel, C.-O. Leong, H. P. Ciolino, G. C. Yeh, C. Hose, J. B. Trepel, M. F. G. Stevens, E. A. Sausville and A. I. Loaiza-Pérez, DNA damage and cell cycle arrest induced by 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203, NSC 703786) is attenuated in aryl hydrocarbon receptor deficient MCF-7 cells,88 (2003) 599-605; DOI:10.1038/sj.bjc.6600722
    Open DOISearch in Google Scholar
  4. G. Mortimer, G. Wells, J.-P. Grochard, E. L. Stone, T. D. Bradshaw, M. F. G. Stevens and A. D. Westwell, Antitumor benzothiazoles. 26. 2-(3,4-dimethoxyphenyl)-5-fluoro benzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potents and selective inhibitory activity against lung, colon, and breast cancer cell lines,49 (2006) 179-185; DOI: 10.1021/jm050942k.
    Open DOISearch in Google Scholar
  5. G. Wells, J. M. Berry, T. D. Bradshaw, A. M. Burger, A. Seaton, B. Wang, A. D. Westwell and M. F. G. Stevens, Substituted -4-hydroxycyclohexa-2,5-dien-1-ones with selective activities against colon and renal cancer cell lines,46 (2003) 532-541; DOI:10.1021/jm020984y.
    Open DOISearch in Google Scholar
  6. T. D. Bradshaw and A. D. Westwell, The development of the antitumor benzothiazole prodrug, Phortress, as a clinical candidate,11 (2004) 1009-1021.
    Open DOISearch in Google Scholar
  7. M. Yoshida, I. Hayakawa, N. Hayashi, T. Agatsuma, Y. Oda, F. Tanzawa, S. Iwasaki, K. Koyama, H. Furukawa, S. Kurakata and Y. Sugano, Synthesis and biological evaluation of benzothiazole derivatives as potent antitumor agents,15 (2005) 3328-3333; DOI:10. 1016/j.bmcl.2005.05.077.
    Open DOISearch in Google Scholar
  8. I. Hutchinson, T. D. Bradshaw, C. S. Matthews, M. F. G. Stevens and A. D. Westwell, Antitumour benzothiazoles. Part 20: 3'-cyano and 3'-alkynyl-substituted 2-(4'-aminophenyl)benzothiazoles as new potent and selective analogues,13 (2003) 471-474; DOI: 10.1016/S0960-894X(02)00930-7.
    Open DOISearch in Google Scholar
  9. T. Akhtar, M. K. Rauf, M. Ebihara and S. Hameed, 2-(3,4-Dichlorophenoxy)propionic acid.E63 (2007) 2590-2592; DOI: 10.1107/S1600536807014249.
    Open DOISearch in Google Scholar
  10. R. Moumne, S. Lavielle and P. Karoyan, Efficient synthesis of 2-amino acid by homologation of β-amino acids involving the reformatsky reaction and mannich-type imminium electrophile,71 (2006) 3332-3334; DOI: 10.1021/jo060316a.
    Open DOISearch in Google Scholar
  11. M. C. Alley, D. A. Scudiero, A. Monks, M. L. Hursey, M. J. Czerwinski, D. L. Fine, B. J. Abbott, L. G. Mayo, R. H. Schoemaker and M. R. Boyd, Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay,48 (1988) 589-601.
    Search in Google Scholar
  12. G. Yang, L. Xu, and A. Lu, Synthesis and bioactivity of novel triazolo [1,5-]pyrimidine derivatives,12 (2001) 491-498; DOI: 10.1002/hc.1075.
    Open DOISearch in Google Scholar
  13. S. D. Young, S. F. Britcher, L. O. Tran, L. S. Payne, W. C. Lumma, T. A. Lyle, J. R. Huff, P. S. Anderson, D. B. Olsen, S. S. Carroll, D. J. Pettibone, J. A. Obrien, R. G. Ball, S. K. Balani, J. H. Lin, I. W. Chen, W. A. Schleif, V. V. Sardana, W. J. Long, V. W. Byrnes and E. A. Emini, Novel, highly potent non-nucleoside inhibitor of the human immunodeficiency-virus type-1 reverse transcriptase,39 (1995) 2602-2605.
    Open DOISearch in Google Scholar
  14. E. De Clercq, Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections,16 (2003) 569-596; DOI: 10.1128/CMR.16.4.
    Search in Google Scholar
  15. R. B. Weiss, The anthracyclines:, 19 (1992) 670-686.
    Search in Google Scholar
  16. C. D. Hose, M. Hollingshead, E. A. Sauville and A. Monks, Induction of CYP1A1 in tumor cells by the antitumor agent 2-[4-amino-3-methylphenyl]-5-fluoro-benzothizole: A potential surrogate marker for patient sensitivity,2 (2003) 1265-1272.
    Search in Google Scholar
  17. D. Shi, T. D. Bradshaw, S. Wrigley, C. J. McCall, P. Lelieveld, I. Fichtner and M. F. G. Stevens, Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell linesand39 (1996) 3375-3384; DOI:10.1021/jm9600959.
    Open DOISearch in Google Scholar
  18. T. D. Bradshaw, S. Wrigley, R. J. Schultz, K. D. Paull and M. F. G. Stevens, 2-(4-Aminophenyl) benzothiazoles: novel agents with selective profiles ofantitumor activity,77 (1998) 745-752.
    Search in Google Scholar
  19. A. Rana, N. Siddiqui and S. A. Khan, Benzothiazoles: a new profile of biological activities,69 (2007) 10-17.
    Search in Google Scholar
  20. G. Trapani, M. Franco, A. Latrofa, A. Reho and G. Liso, Synthesis,andcytotoxicity, and prediction of the intestinal absorption of substituted 2-ethoxycarbonyl-imidazo[2,1-] benzothiazoles,14 (2001) 209-216; DOI: 10.1016/S0928-0987(01)00173-7.
    Open DOISearch in Google Scholar
  21. K. J. Watson, D. R. Anderson and S. T. Nguyen, Toward polymeric anticancer drug cocktails from ring-opening metathesis polymerization,34 (2001) 3507-3509; DOI:10.1016/S0928-0987(01)00173-7.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/v10007-008-0007-2 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Journal RSS Feed
Language: English, Croatian
Page range: 135 - 149
Published on: May 30, 2008
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Keywords:
1,3,4-oxathiazoles,
substituted benzothiazoles,
antitumor activity,
antiviral activity
Related subjects:
Pharmacy,
Pharmacy, other

© 2008 Tashfeen Akhtar, Shahid Hameed, Najim Al-Masoudi, Roberta Loddo, Paolo Colla, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

Volume 58 (2008): Issue 2 (June 2008)
Next article