Have a personal or library account? Click to login
Screening for antidepressant, sedative and analgesic activities of novel fused thiophene derivatives Cover

Screening for antidepressant, sedative and analgesic activities of novel fused thiophene derivatives

Open Access
|Mar 2008

References

  1. E. Palaska, M. Aytemir, I. T. Uzbay and D. Erol, Synthesis and antidepressant activities of some 3,5-diphenyl-2-pyrazolines, Eur. J. Med. Chem., 36 (2001) 539-543; DOI: 10.1016/S0223-5234(01)01243-0.10.1016/S0223-5234(01)01243-0
  2. M. F. Şahin, B. Badieogh, M. Gökçe, E. Küpeli, E. Yesilada, Synthesis and analgesic and antiinflammatory activity of methyl 6-substituted-3(2H)-pyridazinone-2-yl acetate derivatives, Arch. Pharm.337 (2004) 445-452.10.1002/ardp.200400896
  3. A. A. Bilgin, E. Palaska, R. Sunal and B. Gumusel, 1,3,5-Triphenyl-2-pyrazolines with antidepressant activities, Pharmazie49 (1994) 67-69.
  4. O. M. E. Abdel-Salam and S. M. Nofal and S. M. El-Shenawy, Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rats, Pharmacol. Res.48 (2003) 157-165; DOI: 10.1016/S1043-6618(03)00106-3.10.1016/S1043-6618(03)00106-3
  5. M. Vrethem, J. Boivie, H. Arnqvist, H. Holmgren, T. Lindstrom and L. H. Thorell, A comparison of amitriptyline and maprotiline in the treatment of painful polyneuropathy in diabetics and non-diabetics, Clin. J. Pain13 (1997) 313-323; DOI: 10.1079/00002508-199712000-00009.
  6. S. S. Bahekar and D. B. Shinde, Synthesis and anti-inflammatory activity of some [4,6-(4-substiuted aryl)-2-thioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl]-acetic acid derivatives, Bioorg. Med. Chem. Lett.14 (2004) 1733-1736.10.1016/j.bmcl.2004.01.039
  7. J. P. Beck, M. A. Curry, R. J. Chorvat, L. W. Fitzgerald, P. J. Gilligan, R. Zaczek and G. L. Trainor, Thiazolo[4,5-d]pyrimidine thiones and -ones as corticotropin-releasing hormone (CRH-R1) receptor antagonists, Bioorg. Med. Chem. Lett.9 (1999) 1185-1188.10.1016/S0960-894X(99)00159-6
  8. V. Alagarsamy, S. Meena, K. V. Ramseshu, V. R. Solomon, K. Thirumurugan, K. Dhanabal and M. Murugan, Synthesis, analgesic, anti-inflammatory, ulcerogenic index and antibacterial activities of novel 2-methylthio-3-substituted-5,6,7,8-tetrahydrobenzo-(b)thieno[2,3-d]pyrimidin-4 (3H)-ones, Eur. J. Med. Chem.41 (2006) 1293-1300.10.1016/j.ejmech.2006.06.00516928409
  9. W. W. Wardakhan, H. M. Gaber, S. A. Ouf and S. M. Sherif, Studies on 2-aminothiophenes: synthesis, transformations and biological evaluation of functionally substituted thiophenes and their fused derivatives, Phosph. Sul. Sil.180 (2005) 601-618; DOI: 10.1080/104265090517406.10.1080/104265090517406
  10. W. W. Wardakhan, H. Z. Shams and H. E. Moustafa, Synthesis of polyfunctionally substituted thiophene, thieno[2,3-b]pyridine and thieno[2,3-d]pyrimidine derivatives, Phosph. Sul. Sil.180 (2005) 1815-1827; DOI: 10.1080/104265090889422.10.1080/104265090889422
  11. W. W. Wardakhan, G. A. Elmegeed, F. M. Manhi, Utility of 2-aminothiophene-3-carboxamide in the synthesis of biologically active fused heterocyclic derivatives, Phosph. Sul. Sil.180 (2005) 125-140; DOI: 10.1080/104265090889422.10.1080/104265090889422
  12. W. W. Wardakhan and S. A. Ouf, Reaction of cyanoacetamide with benzoyl isothiocyanate: synthesis of pyridine, pyrido[2,2-a]-1,2,3-triazine, pyrazolo[3,4-d]-1,2,3-triazine and thiazole derivatives, Egypt. J. Chem.48 (2005) 393-406.
  13. J. Graff, S. Harder, O. Wahl, E. H. Scheuermann and J. Gossmann, Anti-inflammatory effects of clopidogrel intake in renal transplant patients: effects on platelet-leukocyte interactions, platelet CD40 ligand expression, and proinflammatory biomarkers, Clin. Pharmacol. Ther.78 (2005) 468-476.
  14. A. Hymete, J. Rohloff, H. Kjosen and T. H. Iversen, Acetylenic thiophenes from the roots of Escinops ellenbeckii from Ethiopia, Nat. Prod. Res.19 (2005) 755-761; DOI: 10.1080/1478641042000301711.10.1080/147864104200030171116317830
  15. R. A. Tapia, L. Alegria, C. D. Pessoa, C. Salas, M. J. Cortes, J. A. Valderrama, M. E. Sarciron, F. Pautet, N. Walchshofer and H. Fillion, Synthesis and antiprotozoal activity of naphthofuranquinones and naphthothiophenequinones containing a fused thiazole ring, Bioorg. Med. Chem.11 (2003) 2175-2182; DOI: 10.1016/S0968-0896(03)00122-6.10.1016/S0968-0896(03)00122-6
  16. P. Dallemagne, L. P. Khanh, A. Alsaidi, I. Varlet, V. Collot, M. Paillet, R. Bureau and S. Rault, Synthesis and biological evaluation of five-membered heterocycles fused to cyclopenta[c]thiophene as new antitumer agents, Bioorg. Chem.11 (2003) 1161-1167; DOI: 10.1016/S0968-0896(02)00654-5.10.1016/S0968-0896(02)00654-5
  17. M. E. Migaud, R. C. Wilmouth, G. I. Mills, G. J. Wayne, C. Risley, C. Chambers, S. J. F. Macdonald and C. J. Schofield, 5,5-Fused thiophene gamma-lactams as templates for serine protease inhibition, Chem. Com.12 (2002) 1274-1275.10.1039/b111627d12109112
  18. M. Pietsch and M. Gutschow, Alternate substrate inhibition of cholesterol esterase by thieno [2,3-d][1,3]oxazin-4-ones, J. Biol. Chem.277 (2002) 24006-24013.10.1074/jbc.M11225220011959857
  19. R. M. Mohareb and F. M. Manhi, Reaction of 2-diazo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylate with 3-iminobutyronitrile: synthesis of thiophene and their fused derivatives, Heteroatom. Chem.11 (2000) 403-412; DOI: 10.1002/1098-1071(2000).
  20. W. W. Wardakhan, N. A. Louca and M. M. Kamel, The reaction of 2-aminocyclohexeno-[b]thiophene derivatives with ethoxycarbonylisothiocyanate: synthesis of fused thiophene derivatives with antimicrobial and antifungal activities, Acta Chim.54 (2007) 229-241.
  21. R. D. Porsolt, M. Le Pichon and M. Jalfre, Depression: a new animal model sensitive to antidepressant treatments, Nature266 (1977) 730-732; DOI: 10.1038/266730a0.10.1038/266730a0559941
  22. R. Koster, M. Anderson and E. J. De Beer, Acetic acid for analgesic screening, Fed. Proc.18 (1959) 412-413.
  23. S. Reyes and K. Burgess, On formation of thiohydantoins from amino acids under acylation conditions, J. Org. Chem.71 (2006) 2507-2509; DOI: 10.102/jo052576.10.1021/jo052576i16526805
DOI: https://doi.org/10.2478/v10007-007-0041-5 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
Language: English
Page range: 1 - 14
Published on: Mar 12, 2008
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Related subjects:

© 2008 Wagnat Wardakhan, Omar Abdel-Salam, Gamal Elmegeed, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

Volume 58 (2008): Issue 1 (March 2008)