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Chitosan inserts for periodontitis: Influence of drug loading, plasticizer and crosslinking on in vitro metronidazole release Cover

Chitosan inserts for periodontitis: Influence of drug loading, plasticizer and crosslinking on in vitro metronidazole release

Acta Pharmaceutica
Volume 57 (2007): Issue 4 (December 2007)
By: ,  ,  ,   and    
Open Access
|Dec 2007
References

References

  1. P. Axelsson and J. Lindhe, Effect of controlled oral hygiene procedures on caries and periodontal disease in adults,(1978) 133-151; DOI: 10.1111/j.1600-051X.1978.tb01914.x.
    Open DOISearch in Google Scholar
  2. N. J. Medlicott, I. G. Tucker and D. W. Holborow, Delivery systems for the administration of drugs to the periodontal pocket,(1994) 181-203; DOI: 10.1016/0169-409X (94)90033-7.
    Search in Google Scholar
  3. J. Slots and T. E. Rams, Antibiotics in periodontal therapy: advantages and disadvantages,(1990) 479-93.
    Open DOISearch in Google Scholar
  4. T. S. Kim, T. Burklin, B. Schacher, P. Ratka-Kruger, M. T. Schaecken, H. H. Renggli, W. Fiehn and P. Eickholz, Pharmacokinetic profile of a locally administered doxycycline gel in crevicular fluid, blood, and saliva,(2002) 1285-1291; DOI: 10.1902/jop.2002.73.11.1285.
    Open DOISearch in Google Scholar
  5. K. Schwach-Abdellaoui, N. Vivien-Casioni and R. Gurny, Local delivery of antimicrobial agents for the treatment of periodontal disease,(2000) 83-99; DOI: 10.1016/ S0939-6411(00)00086-2.
    Open DOISearch in Google Scholar
  6. T. Chandy and C. P. Sharma, Chitosan as a biomaterial,(1990) 1-24.
    Open DOISearch in Google Scholar
  7. R. Muzzarelli, V. Baldassarre, F. Conti, P. Ferrara and G. Biagini, Biological activity of chitosan: ultrastructural study,(1988) 247-252; DOI: 10.1016/0142-9612(88)90092-0.
    Open DOISearch in Google Scholar
  8. J. Lindhe, A. D. Haffajee and S. S. Socransky, Progression of periodontal disease in adult subjects in the absence of periodontal therapy,(1983) 433-442; DOI: 10.1111/ j.1600-051X.1983.tb01292.x.
    Open DOISearch in Google Scholar
  9. H. N. Newman, F. I. S. Yeung, W. Z. A. B. Wan-Yusof and M. Addy, Slow release metronidazole and a simplified mechanical oral hygiene regimen in the control of chronic periodontitis,(1984) 576-582; DOI: 10.1111/j.1600-051X.1984.tb00910.x.
    Open DOISearch in Google Scholar
  10. F. A. Gusberti, S. A. Syed and N. P. Long, Combined antibiotic (metronidazole) and mechanical treatment effects on the subgingival bacterial flora of sites with recurrent periodontal disease,(1988) 353-359; DOI: 10.1111/j.1600-051X.1988.tb01011.x.
    Open DOISearch in Google Scholar
  11. W. J. Loesche, Antibiotic therapy as part of periodontal therapy,(1989) 95-104.
    Search in Google Scholar
  12. M. A. Van-Oosten, F. J. Notten and F. H. Mikx, Metronidazole concentrations in human plasma, saliva, and gingival crevice fluid after a single dose,(1986) 1420-1423.
    Open DOISearch in Google Scholar
  13. V. Pedrazzoli, M. Kilian and T. Karring, Comparative clinical and microbiological effects of topical subgingival application of metronidazole 25% dental gel and scaling in the treatment of adult periodontitis,(1992) 715-722.
    Open DOISearch in Google Scholar
  14. C. Hitzig, T. Fosse, Y. Charbit, C. Bitton and L. Hannoun, Effects of combined topical metronidazole and mechanical treatment on the subgingival flora in deep periodontal pockets in cuspids and bicuspids,(1997) 613-617.
    Open DOISearch in Google Scholar
  15. K. Stolze, Concentration of metronidazole in periodontal pockets after application of a metronidazole 25% dental gel,(1992) 698-701.
    Open DOISearch in Google Scholar
  16. K. Stolze and M. Stellfield, Systemic absorption of metronidazole after application of a metronidazole 25% dental gel,(1992) 693-697.
    Open DOISearch in Google Scholar
  17. J. Ainamo, T. Lie, B. H. Ellingsen, B. F. Hansen, L. A. Johansson, T. Karring, J. Kisch, K. Paunio and K. Stolze, Clinical responses to subgingival application of a metronidazole 25% gel compared to the effect of subgingival scaling in adult periodontitis.(1992) 723-729.
    Search in Google Scholar
  18. K. Oungbho and B. W. Muller, Chitosan sponges as sustained release drug carriers,(1997) 229-237; DOI: 10.1016/S0378-5173(97)00201-9.
    Open DOISearch in Google Scholar
  19. R. Barat, A. Srinatha, J. K. Pandit, D. Ridhurkar, J. Balasubramaniam, N. Mittal and D. N. Mishra, Niridazole biodegradable inserts for local long term treatment of periodontits: Possible new life for an orphan drug,(2006) 365-373; DOI: 10.1080/10717540500398126.
    Open DOISearch in Google Scholar
  20. T. Higuchi, Mechanism of sustained action medication, theoretical analysis of rate of solid drug dispersed in solid matrices,(1963) 1145-1149; DOI: 10.1002/jps.2600521210.
    Open DOISearch in Google Scholar
  21. R. W. Korsmeyer, R. Gurny, E. M. Doelker, P. Buri and N. A. Peppas, Mechanism of solute release from porous hydrophilic matrices,(1983) 25-35; DOI: 10.1016/0378-5173 (83)90064-9.
    Search in Google Scholar
  22. Z. J. Shao, L. Morales, S. Diaz and N. A. Muhammad, Drug release from kollicoat SR 30D-coated nonpareil beads: evaluation of coating, plasticizer type, and curing condition,(2002) article 15.
    Open DOISearch in Google Scholar
  23. D. Thacharodi and K. P. Rao, Development andevaluation of chitosan-based transdermal drug delivery systems for the controlled release of propranolol hydrochloride,(1995) 145-148; DOI: 10.1016/0142-9612(95)98278-M.
    Open DOISearch in Google Scholar
  24. E. O. Cetin, N. Buduneli, E. Atlihan and L. Kirilmaz,studies of a degradable device for controlled release of meloxicam,(2005) 773-777; DOI: 10.1111/j.1600-051X.2005.00755.x.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/v10007-007-0037-1 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English, Croatian
Page range: 469 - 477
Published on: Dec 28, 2007
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Keywords:
chitosan inserts,
cross-linking,
metronidazole,
periodontitis,
sustained release
Related subjects:
Pharmacy,
Pharmacy, other

© 2007 Romi Barat, Anegundha Srinatha, Jayanta Pandit, Shampa Anupurba, Neelam Mittal, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

Volume 57 (2007): Issue 4 (December 2007)
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