Skip to main content
Have a personal or library account? Click to login
Application of Recombinant DNA Methods for Production of Cholinesterases as Organophosphate Antidotes and Detectors Cover

Application of Recombinant DNA Methods for Production of Cholinesterases as Organophosphate Antidotes and Detectors

Archives of Industrial Hygiene and Toxicology
Volume 58 (2007): Issue 3 (September 2007)
By: ,  ,   and    
Open Access
|Oct 2007
References

References

  1. Taylor P. Anticholinesterase Agents in Goodman and Gilman's Pharmacological Basis of Therapeutics. 10ed. New York: McGraw-Hill; 2005.
    Search in Google Scholar
  2. Taylor P, Kovarik Z, Reiner E, Radić Z. Acetylcholinesterase: Converting a vulnerable target to a template for antidotes and detection of inhibitor exposure.2007;233:70-8.
    Open DOISearch in Google Scholar
  3. Giacobini E, editor. Cholinesterases and Cholinesterase Inhibitors. London: Martin Dunitz; 2000.
    Search in Google Scholar
  4. Wilson IB. Molecular complementarity and antidotes for organophosphate poisoning.1959;18:752-8.
    Search in Google Scholar
  5. Schumacher M, Camp S, Maulet Y, Newton M, Mac-Phee-Quigley K, Taylor S, Friedmann T, Taylor P. Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence.1986319:407-9.
    Open DOISearch in Google Scholar
  6. Rachinsky T, Camp S, Li Y, Ekstrom TJ, Newton M, Taylor P. Molecular cloning of mouse acetylcholinesterase: Tissue distribution of alternatively spliced mRNA species.1990;5:317-27.
    Open DOISearch in Google Scholar
  7. Lockridge O, Bartels CF, Vaughan TA, Wong CK, Norton SE, Johnson LL. Complete amino acid sequence of human serum cholinesterase.1987;262:549-57.
    Open DOISearch in Google Scholar
  8. Sussman JL, Harel M, Frolow F, Oefner C, Goldman A, Toker L, Silman I. Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine binding protein.1991;253:872-9.
    Open DOISearch in Google Scholar
  9. Bourne Y, Taylor P, Marchot P. Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex.1995;83:493-506.
    Open DOISearch in Google Scholar
  10. Radić Z. Pickering N, Vellom DC, Camp S, Taylor P. Three distinct domains in the cholinesterase molecule confer selectivity of acetyl- and butyrylcholinesterase inhibitors.1993;32:12074-84.
    Open DOISearch in Google Scholar
  11. Shafferman A, Ordentlich A, Barak D, Kronman C, Ber R, Bino T, Ariel N, Osman R, Velan B. Electrostatic attraction by surface charge does not contribute to the catalytic efficiency of acetylcholinesterase.199413:3448-55.
    Open DOISearch in Google Scholar
  12. Radić Z, Kirchoff PD, Quinn DM, McCammon JM, Taylor P. Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase.1997;272:23265-77.
    Open DOISearch in Google Scholar
  13. Lewis WG, Green LG, Gynszpan F, Radić Z, Carlier PR, Taylor P, Finn MG, Sharpless KB. Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of femtomolar inhibitor from an array of building blocks.2002;41:1053-7.
    Open DOISearch in Google Scholar
  14. Manetsch R, Kransinski A, Radić Z, Raushel J, Taylor P, Sharpless KB, Kolb HC. In situ click chemistry: enzyme inhibitors made to their own specifications.2004;126:12809-18.
    Open DOISearch in Google Scholar
  15. Bourne Y, Kolb HC, Radić Z, Sharpless KB Taylor P, Marchot P. Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation.2004;101:1449-54.
    Open DOISearch in Google Scholar
  16. Radić Z, Manetsch R, Fournier D, Sharpless KB, Taylor P. Probing gorge dimensions of cholinesterases by freeze-frame click chemistry. In: The IXInternational Meeting on Cholinesterases; 6-10 May 2007; Suzhou, China. Program Book. p. 40. Abstract S-IV-2.
    Search in Google Scholar
  17. Wilson IB, Ginsburg S. A powerful reactivator of alkylphosphate-inhibited acetylcholinesterase.1955;18:168-70.
    Open DOISearch in Google Scholar
  18. Ashani Y, Radić Z, Tsigelny I, Vellom DC, Pickering NA, Quinn DC, Doctor BP, Taylor P. Aminoacid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono-and bisquaternary oximes.1995;270:6370-80.
    Open DOISearch in Google Scholar
  19. Hosea NA, Berman HA, Taylor P. Specificity and orientation of trigonal carboxyl esters and tetrahedral alkyl phosphonyl esters in cholinesterases.1995;34:11528-36.
    Open DOISearch in Google Scholar
  20. Wong L, Radić Z, Brüggeman RJM, Hosea N, Berman HA, Taylor P. Mechanism of oxime reactivation of acetylcholinesterase analyzed by chirality and mutagnesis.2000;39:5750-7.
    Open DOISearch in Google Scholar
  21. Kovarik Z, Radić Z, Berman HA, Simeon-Rudolf V, Reiner E, Taylor P. Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates.2004;43:3222-9.
    Open DOISearch in Google Scholar
  22. Kovarik Z, Radić Z, Berman HA, Simeon-Rudolf V, Reiner E, Taylor P. Acetylcholinestrerase active center and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates.2003;373:33-40.
    Open DOISearch in Google Scholar
  23. Wang L, Jackson WC, Steinbach PA, Tsien RY. Evolution of new non-antibody proteins via iterative somatic hypermutation.2004;101:16745-9.
    Open DOISearch in Google Scholar
  24. Shi J, Radić Z, Taylor P. Inhibitors of different structure induce distinguishing conformations in the omega loop, Cys-Cys, of mouse acetylcholinesterase.2002;277:43301-8.
    Open DOISearch in Google Scholar
  25. Shi J, Tai K, McCammon JA, Taylor P, Johnson DA. Nanosecond dynamics of mouse acetylcholinesterase Cys-Cysomega loop.2003;278:30905-11.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/v10004-007-0027-1 | Journal eISSN: 1848-6312 (formerly 0004-1254) | Journal ISSN: 0004-1254
Journal RSS Feed
Language: English, Croatian
Page range: 339 - 345
Published on: Oct 3, 2007
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Keywords:
acetylcholinesterase,
fluorescent acetylcholinesterase,
organophosphate inhibitors,
oxime antidotes,
oxime-assisted catalysis,
reactivation kinetics,
remote detection,
in situ-click chemistry,
template-guided drug design
Related subjects:
Medicine,
Basic medical science,
Basic medical science, other

© 2007 Palmer Taylor, Elsa Reiner, Zrinka Kovarik, Zoran Radić, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.

Volume 58 (2007): Issue 3 (September 2007)
Previous article
Next article