References
- Taylor P. Anticholinesterase Agents in Goodman and Gilman's Pharmacological Basis of Therapeutics. 10th ed. New York: McGraw-Hill; 2005.
- Taylor P, Kovarik Z, Reiner E, Radić Z. Acetylcholinesterase: Converting a vulnerable target to a template for antidotes and detection of inhibitor exposure. Toxicology 2007;233:70-8.
- Giacobini E, editor. Cholinesterases and Cholinesterase Inhibitors. London: Martin Dunitz; 2000.
- Wilson IB. Molecular complementarity and antidotes for organophosphate poisoning. Fed Proc 1959;18:752-8.
- Schumacher M, Camp S, Maulet Y, Newton M, Mac-Phee-Quigley K, Taylor S, Friedmann T, Taylor P. Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence. Nature 1986319:407-9.
- Rachinsky T, Camp S, Li Y, Ekstrom TJ, Newton M, Taylor P. Molecular cloning of mouse acetylcholinesterase: Tissue distribution of alternatively spliced mRNA species. Neuron 1990;5:317-27.
- Lockridge O, Bartels CF, Vaughan TA, Wong CK, Norton SE, Johnson LL. Complete amino acid sequence of human serum cholinesterase. J Biol Chem 1987;262:549-57.
- Sussman JL, Harel M, Frolow F, Oefner C, Goldman A, Toker L, Silman I. Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine binding protein. Science 1991;253:872-9.
- Bourne Y, Taylor P, Marchot P. Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex. Cell 1995;83:493-506.
- Radić Z. Pickering N, Vellom DC, Camp S, Taylor P. Three distinct domains in the cholinesterase molecule confer selectivity of acetyl- and butyrylcholinesterase inhibitors. Biochemistry 1993;32:12074-84.
- Shafferman A, Ordentlich A, Barak D, Kronman C, Ber R, Bino T, Ariel N, Osman R, Velan B. Electrostatic attraction by surface charge does not contribute to the catalytic efficiency of acetylcholinesterase. EMBO J 199413:3448-55.
- Radić Z, Kirchoff PD, Quinn DM, McCammon JM, Taylor P. Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase. J Biol Chem 1997;272:23265-77.
- Lewis WG, Green LG, Gynszpan F, Radić Z, Carlier PR, Taylor P, Finn MG, Sharpless KB. Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of femtomolar inhibitor from an array of building blocks. Angew Chem 2002;41:1053-7.
- Manetsch R, Kransinski A, Radić Z, Raushel J, Taylor P, Sharpless KB, Kolb HC. In situ click chemistry: enzyme inhibitors made to their own specifications. J Am Chem Soc 2004;126:12809-18.
- Bourne Y, Kolb HC, Radić Z, Sharpless KB Taylor P, Marchot P. Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation. Proc Natl Acad Sci USA 2004;101:1449-54.
- Radić Z, Manetsch R, Fournier D, Sharpless KB, Taylor P. Probing gorge dimensions of cholinesterases by freeze-frame click chemistry. In: The IXth International Meeting on Cholinesterases; 6-10 May 2007; Suzhou, China. Program Book. p. 40. Abstract S-IV-2.
- Wilson IB, Ginsburg S. A powerful reactivator of alkylphosphate-inhibited acetylcholinesterase. Biochim Biophys Acta 1955;18:168-70.
- Ashani Y, Radić Z, Tsigelny I, Vellom DC, Pickering NA, Quinn DC, Doctor BP, Taylor P. Aminoacid residues controlling reactivation of organophosphonyl conjugates of acetylcholinesterase by mono-and bisquaternary oximes. J Biol Chem 1995;270:6370-80.
- Hosea NA, Berman HA, Taylor P. Specificity and orientation of trigonal carboxyl esters and tetrahedral alkyl phosphonyl esters in cholinesterases. Biochemistry 1995;34:11528-36.
- Wong L, Radić Z, Brüggeman RJM, Hosea N, Berman HA, Taylor P. Mechanism of oxime reactivation of acetylcholinesterase analyzed by chirality and mutagnesis. Biochemistry 2000;39:5750-7.
- Kovarik Z, Radić Z, Berman HA, Simeon-Rudolf V, Reiner E, Taylor P. Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates. Biochemistry 2004;43:3222-9.
- Kovarik Z, Radić Z, Berman HA, Simeon-Rudolf V, Reiner E, Taylor P. Acetylcholinestrerase active center and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates. Biochem J 2003;373:33-40.
- Wang L, Jackson WC, Steinbach PA, Tsien RY. Evolution of new non-antibody proteins via iterative somatic hypermutation. Proc Natl Acad Sci USA 2004;101:16745-9.
- Shi J, Radić Z, Taylor P. Inhibitors of different structure induce distinguishing conformations in the omega loop, Cys69-Cys96, of mouse acetylcholinesterase. J Biol Chem 2002;277:43301-8.
- Shi J, Tai K, McCammon JA, Taylor P, Johnson DA. Nanosecond dynamics of mouse acetylcholinesterase Cys69-Cys96 omega loop. J Biol Chem 2003;278:30905-11.