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Changes In Liver and Brain Cytochrome P450 after Multiple Cocaine Administration, Alone and in Combination with Nifedipine Cover

Changes In Liver and Brain Cytochrome P450 after Multiple Cocaine Administration, Alone and in Combination with Nifedipine

Open Access
|Oct 2007

References

  1. Filip M, Frankowska M, Zaniewska M, Golda A, Przegalinski E. The serotonergic system and its role in cocaine addiction. Pharmacol Rep 2005;57:685-700.
  2. Sun L, Lau CE. Simultaneous pharmacokinetic modeling of cocaine and its metabolites, norcocaine and benzoylecgonine, after intravenous and oral administration in rats. Drug Metab Dispos 2001;29:1183-9.
  3. Arinc E, Bozcaarmutlu A. Catalyzation of cocaine N-demethylation by cytochromes P4502B, P4503A, and P4502D in fish liver. J Biochem Mol Toxicol 2003;17:169-76.10.1002/jbt.10075
  4. Liu XQ, Ren YL, Qian ZY, Wang GJ. Enzyme kinetics and inhibition of nimodipine metabolism in human liver microsomes. Acta Pharmacol Sin 2000;21:690-4.
  5. Vetulani J. Calcium and voltage-dependent calcium channels. Kismos 1997;46:491-505.
  6. etulani J. Drug addiction. Part III. Pharmacotherapy of addiction. Pol J Pharmacol 2001;53:415-35.
  7. Vitcheva V, Mitcheva M. Effects of Nifedipine on behavioral and biochemical parameters in rats after multiple morphine administration. Methods Find Exp Clin Pharmacol 2004;26:631-4.10.1358/mf.2004.26.8.863729
  8. Council of Europe. European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes. CETS No. 123, 1991. [displayed 30 May 2007] Available at http://conventions.coe.int/Treaty/Commun/QueVoulezVous.asp?NT=123&CM=1&CL=ENG
  9. Antkiewicz-Michaluk L, Romanska I, Vetulani J. Ca2+ channel blockade prevents lysergic acid diethylamide-induced changes in dopamine and serotonin metabolism. Eur J Pharmacol 1997;332:9-14.10.1016/S0014-2999(97)01025-X
  10. Itzhak Y, Ali SF, Martin JL, Black MD, Huang PL. Resistance of neuronal nitric oxide synthase-deficient mice to cocaine-induced locomotor sensitization. Psychopharmacol 1998;140:378-86.10.1007/s002130050779
  11. Bhagwat SV, Boyd MR, Ravindranath V. Rat brain cytochrome P 450. Reassessment of monooxygenase activities and cytochrome P450 levels. Drug Metab Disps 1995;23:651-4.
  12. Guengerich FP. Microsomal enzymes involved in toxicology. Analysis and separation. In: Heis AW, editor. Principals and Methods of Toxicology. New York (NY): Raven Press; 1987. p. 609-634.
  13. Omura T, Sato R. The carbon-monoxide-binding pigment of liver microsomes. J Biol Chem 1964;239:2370-85.10.1016/S0021-9258(20)82244-3
  14. Lowry OH. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75.10.1016/S0021-9258(19)52451-6
  15. Antkiewicz-Michaluk L, Michaluk J, Romanska I, Vetulani J. Reduction of morphine dependence and potenciation of analgesia by co-administration of nifedipin. Biopharmacol 1993;111:457-67.
  16. Watson WP, Little JJ. Effects of dihydropiridines on the components of the ethanol withdrawal syndrome: possible evidence for involvement of potassium, as well as calcium? Alcohol Clin Exp Res 1997;21:409-16.10.1111/j.1530-0277.1997.tb03784.x
  17. Haward LA, Sellers EM, Tyndale RF. The role of pharmacogenetically - variable cytochrome P450 in drug abuse and dependence. Pharmacogenomics 2002;3:185-99.10.1517/14622416.3.2.185
  18. Koleva MR, Stoychev TS. Effect of nifedipine, verapamil and diltiazem on the enzyme-inducing activity of phenobarbital and beta-naphthoflavone. Gen Pharmacol 1995;26:225-8.10.1016/0306-3623(94)E0044-M
  19. Kastelova A, Koleva M, Staneva-Stoytcheva D. Changes in rat liver monooxygenase activities after administration of atenolol, nifedipine and diltiazem alone and in combination. Methods Find Exp Clin Pharmacol. 2000;22:627-31.10.1358/mf.2000.22.8.80227411256234
  20. Shuster L, Garhart C, Powers J, Grunfeld Y, Kanel G. Hepatotoxicity of cocaine. NIDA Res Monogr 1988;88:250-75.
  21. Powers JF, Shuster L. Subacute cocaine treatment changes expression of mouse liver cytochrome P450 isoforms. Pharmacology 1999;58:87-100.10.1159/000028271
  22. Pasanen M, Pellinen P, Stenback F, Juvonen RO, Raunio H, Pelkonen O. The role of CYP enzymes in cocaineinduced liver damage. Arch Toxicol 1995;69:287-90.10.1007/s002040050172
  23. Nabeshima T, Fontenit J, Ho IK. Effect of chronic administration of phenobarbital or morphine on the brain micrisomal cytochrome P450 system. Biochem Pharmacol 1981;30:1142-5.10.1016/0006-2952(81)90456-1
DOI: https://doi.org/10.2478/v10004-007-0019-1 | Journal eISSN: 1848-6312 | Journal ISSN: 0004-1254
Language: English, Slovenian
Page range: 287 - 291
Published on: Oct 3, 2007
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2007 Vessela Vitcheva, Mitka Mitcheva, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons License.

Volume 58 (2007): Issue 3 (September 2007)