Demographic characteristics of mumps cases, infectious disease surveillance system, Czech Republic, 2013–2022_
| Number of mumps cases (n=11,913) | Proportion (%) | Incidence of mumps cases per 100,000 population and year | |
|---|---|---|---|
| Year of onset | |||
| 2013 | 1,553 | 13.0 | 14.8 |
| 2014 | 677 | 5.7 | 6.4 |
| 2015 | 1,616 | 13.6 | 15.3 |
| 2016 | 5,733 | 48.1 | 54.3 |
| 2017 | 1,407 | 11.8 | 13.3 |
| 2018 | 537 | 4.5 | 5.1 |
| 2019 | 191 | 1.6 | 1.8 |
| 2020 | 93 | 0.8 | 0.9 |
| 2021 | 38 | 0.3 | 0.4 |
| 2022 | 68 | 0.6 | 0.6 |
| Distribution of cases by administrative region | |||
| Prague | 1,041 | 8.7 | 8.1 |
| Central Bohemian | 853 | 7.2 | 6.3 |
| South Bohemian | 2,438 | 20.5 | 38.1 |
| Plzeň | 446 | 3.7 | 7.7 |
| Karlovy Vary | 274 | 2.3 | 9.3 |
| Ústí nad Labem | 386 | 3.2 | 4.7 |
| Liberec | 602 | 5.1 | 13.7 |
| Hradec Králové | 649 | 5.4 | 11.8 |
| Pardubice | 821 | 6.9 | 15.8 |
| Vysočina | 1,642 | 13.8 | 32.2 |
| South Moravian | 798 | 6.7 | 6.7 |
| Olomouc | 381 | 3.2 | 6.0 |
| Zlín | 240 | 2.0 | 4.1 |
| Moravian-Silesian | 1,342 | 11.3 | 11.1 |
| Gender | |||
| Male | 6,885 | 57.8 | 13.2 |
| Female | 5,028 | 42.2 | 9.3 |
| Age group (years) | |||
| 0 | 10 | 0.1 | 0.9 |
| 1–4 | 269 | 2.3 | 6.0 |
| 5–9 | 1,371 | 11.5 | 24.1 |
| 10–14 | 3,417 | 28.7 | 64.8 |
| 15–19 | 3,142 | 26.4 | 65.5 |
| 20–24 | 1,353 | 11.4 | 24.8 |
| 25–34 | 1,479 | 12.4 | 10.6 |
| 35–44 | 506 | 4.2 | 3.0 |
| 45–54 | 214 | 1.8 | 1.5 |
| 55–64 | 95 | 0.8 | 0.7 |
| 65–74 | 46 | 0.4 | 0.4 |
| 75+ | 11 | 0.1 | 0.1 |
Mumps complications in MMR vaccinated patients by time passed from the second dose, Czech Republic, 2013–2022_
| Time from the second dose (in years) | Number of cases | Number of cases with complications | % of mumps cases with complications | Adjustedb odds ratio | 95% CI | p value |
|---|---|---|---|---|---|---|
| 0–4 | 531 | 1 | 0.2 | Refa | ||
| 5–9 | 2,283 | 26 | 1.1 | Refa | ||
| 10–14 | 3,287 | 151 | 4.6 | 5.26 | 3.45, 8.01 | <0.001 |
| 15–19 | 1,981 | 170 | 8.6 | 10.29 | 6.77, 15.63 | <0.001 |
| 20–24 | 734 | 86 | 11.7 | 14.53 | 9.28, 22.75 | <0.001 |
| 25+ | 194 | 18 | 9.3 | 11.30 | 6.07, 21.06 | <0.001 |
| Total | 9,010 | 452 | 5.0 |
Vaccination and hospitalisation status of mumps cases, infectious disease surveillance system, Czech Republic, 2013–2022_
| Number of mumps cases | Proportion (%) | |
|---|---|---|
| Vaccination status (n=11,913) | 9,714 | 81.5 |
| Vaccinated | 1,673 | 14.0 |
| Unvaccinated | 526 | 4.4 |
| Unknown | ||
| Vaccinated by doses (n=9,714) | ||
| 1 dose | 156 | 1.6 |
| 2 doses | 9,134 | 94.0 |
| 3 doses | 29 | 0.3 |
| Unknown number of vaccine doses | 395 | 4.1 |
| Hospitalisation (n=11,913) | ||
| Yes | 946 | 7.9 |
| No | 10,898 | 91.5 |
| Unknown | 69 | 0.6 |
Mumps complications, hospitalisation and vaccination, infectious disease surveillance system, Czech Republic, 2013–2022_
| Mumps vaccination | ||||||
|---|---|---|---|---|---|---|
| Three doses | Two doses | One dose | Zero doses | Unknown | Total | |
| Total number of cases Complications | 29 | 9,134 | 156 | 1,673 | 921 | 11,913 |
| None | 27 | 8,608 | 145 | 1,339 | 752 | 10,871 |
| Orchitisa | 2 | 312 | 6 | 231 | 82 | 633 |
| Meningitis | 0 | 69 | 0 | 38 | 19 | 126 |
| Pancreatitis | 0 | 20 | 0 | 13 | 4 | 37 |
| Encephalitis | 0 | 3 | 0 | 6 | 2 | 11 |
| Oophoritisb | 0 | 3 | 0 | 5 | 0 | 8 |
| Other | 0 | 54 | 1 | 22 | 11 | 88 |
| Unknown | 0 | 65 | 4 | 19 | 51 | 139 |
| Hospitalisation | ||||||
| Yes | 2 | 494 | 8 | 297 | 145 | 946 |
| No | 27 | 8,605 | 147 | 1,359 | 761 | 10,899 |
| Unknown | 0 | 35 | 1 | 17 | 15 | 68 |
Number of cases with mumps complications or hospitalisation by MMR vaccination status and adjusted MMR vaccine effectiveness, Czech Republic, 2013–2022_
| Type of complications | Vaccination by number of dosesb | Number of cases | Number of cases with complications (%) | Unadjusted odds ratio (95% CI) | Adjustedc odds ratio (95% CI) | p value | Adjustedc vaccine effectiveness % (95% CI) |
|---|---|---|---|---|---|---|---|
| Any complication | 0 | 1,654 | 315 (19.0) | Ref | Ref | ||
| 1 | 152 | 7 (4.6) | 0.21 (0.10, 0.44) | 0.42 (0.19, 0.95) | 0.036 | 58 (5, 81) | |
| 2 | 9,069 | 461 (5.1) | 0.23 (0.20, 0.27) | 0.48 (0.37, 0.62) | <0.001 | 52 (38, 63) | |
| Orchitisa | 0 | 967 | 231 (23.9) | Ref | |||
| 1 | 92 | 6 (6.5) | 0.22 (0.10, 0.52) | 0.57 (0.23, 1.38) | 0.213 | 43 (−38, 77) | |
| 2 | 5,174 | 312 (6.0) | 0.20 (0.17, 0.25) | 0.50 (0.36, 0.68) | <0.001 | 50 (32, 64) | |
| Meningitis | 0 | 1,654 | 38 (2.3) | Ref | |||
| 1 | 152 | 0 (0.0) | 0.14 (0.01, 2.25) | 0.18 (0.01, 3.12) | 0.240 | 82 (−212, 99) | |
| 2 | 9,069 | 69 (0.8) | 0.32 (0.22, 0.48) | 0.41 (0.21, 0.77) | 0.006 | 59 (23, 79) | |
| Pancreatitis | 0 | 1,654 | 13 (0.8) | Ref | |||
| 1 | 152 | 0 (0.0) | 0.40 (0.02, 6.74) | 0.70 (0.03, 14.56) | 0.820 | 30 (−1,356, 97) | |
| 2 | 9,069 | 20 (0.2) | 0.28 (0.14, 0.55) | 0.46 (0.15, 1.44) | 0.181 | 54 (−44, 85) | |
| Hospitalisation | 0 | 1,637 | 296 (18.1) | Ref | |||
| 1 | 151 | 8 (5.3) | 0.25 (0.12, 0.52) | 0.46 (0.22, 0.97) | 0.042 | 54 (3, 78) | |
| 2 | 9,034 | 491 (5.4) | 0.26 (0.22, 0.30) | 0.43 (0.33, 0.56) | <0.001 | 57 (44, 67) |