Have a personal or library account? Click to login
Serum biomarkers associated with malnutrition and nutritional risk in elderly primary care patients: A cross-sectional study from Bosnia and Herzegovina Cover

Serum biomarkers associated with malnutrition and nutritional risk in elderly primary care patients: A cross-sectional study from Bosnia and Herzegovina

Open Access
|Dec 2020

Figures & Tables

Mean ferritin, haemoglobin albumin and total cholesterol concentrations in the Bosnian elderly population by age and gender_

Variable Ferritin, ng/ml
Haemoglobin, g/l
Albumin, g/l
Total cholesterol, mmol/l
Age/yearsN (%)Mean (SD)P*Mean (SD)P*Mean (SD)P*Mean (SD)P*
Men65–7496 (49)227.7 (170.6)0.080146.3 (15.1)<0.00146.2 (3.2)0.0055.3 (1.1)0.004
(n=195)75–8466 (33)170.8 (131.3) 138.5 (17.9) 44.6 (3.1) 5.0 (1.1)
>8533 (16)194.3 (176.2) 135.4 (15.7) 44.6 (3.7) 4.6(1)
Women65–74111 (44)101.6 (6.3)<0.001133.6 (11.9)<0.00146.2 (8.4)0.0625.5 (1)0.031
(n=251)75–84110 (43)119.6 (9.4) 124.2 (13.9) 44.3 (3.8) 5.4 (1.3)
>8530 (12)168.9 (22.7) 117.4 (15.6) 44.4 (4.6) 4.9 (1.2)

Average daily dietary intakes of study participants in comparison with DRI recommendations_

Variable*Study participants’ intake (n=446)DRI Recommendation% DRI
Energy (Cal)1330 (329)1900–230056–70%
Carbohydrate, g224 (79)130>100%
Fat, g32 (13)20–35>91%
Protein, g42 (14)46–5675–91%
Vitamin B6, mg0.84 (0.1)1.5–1.749–56%
Vitamin B12, μg1 (0.6)2.474%
Vitamin C, mg33 (15)75–9036–44 %
Vitamin E, mg2 (2)1533%
Vitamin D, μg2 (0.2)15–2012–16
Magnesium, mg127 (45)320–42030–40%
Zinc, mg4 (1)9–1137–46%
Calcium, mg486 (116)1,20040%
Iron, mg13 (4)8–18>50%
Potassium, g1 (0.6)4.728%
Sodium, g0.60 (455)1.250%
Folate, μg115 (32)40029%

Differences in anthropometric measurements, biomedical analyses and functional parameters in regard to categories of nutritional status per MNA(a) and SCREEN II(b)_

VariableMNA(a)
SCREEN II(b)
Malnutrition/at-risk (N=259)Normal nutrition (N=187)P-value*High risk (N=394)Moderate/low risk (N=52)P-value*
Albumin, g/l44.5 (4.1)45.8 (5.9)0.00445.2 (5.6)45.2 (2.6)0.521
Ferritin, ng/ml157.1 (127.1)153.6 (138.5)0.779156.3 (135.8)144.8 (118.7)0.507
Total cholesterol, mmol/l5.0 (1.2)5.4 (1.7)<0.0015.2 (1.2)5.6 (1)0.035
Haemoglobin, g/l130 (18.9)136.7 (14.5)0.001132.8 (17.5)140.3 (11.0)0.002
Waist circumference (cm)91.9 (13.1)99.0 (12.4)<0.00196.0 (13.7)95.3 (8.5)0.718
Mid-upper arm circumference (cm)25.9 (3.7)27.6 (3.3)<0.00126.8 (3.7)26.9 (2.8)0.953
Skinfold measurement (mm)14.4 (3.5)17.8 (7.3)<0.00115.9 (6.2)19.6 (6.07)0.001
Calf circumference (cm)29.9 (4.3)34.4 (3.5)<0.00132.2 (4.6)33.8 (2.9)0.017
BMI, kg/m225.3 (5.2)28.6 (4.5)<0.00127.0 (5.2)27.8 (2.9)0.269
6-CIT(c)15.7 (5.9)7.2 (5.8)<0.00111.8 (7.2)5.3 (2.9)<0.001
Timed Go and Up Test (secs)23.8 (9.9)13.4 (8.9)<0.00119.1 (10.9)9.7 (4.8)<0.001
Functional Reach Test (cm)18.5 (8.5)31.5 (11.1)<0.00124.2 (11.2)38.2 (10.4)<0.001
Katz Index4.5 (1.9)5.8 (0.8)<0.0015.2 (1.6)6.0 (0)<0.001
Lawton Scale5.4 (3.1)7.6 (1.3)<0.0016.5 (2.7)8.0 (0)<0.001

Variables associated with biochemical biomarkers (multivariate linear regression analyses)_

VariableB
β
95% CI for B
P-valuea
minmax
Albuminb
Meals, 3/day1.550.190.732.22<0.001
Fruit/vegetable servings-0.59-0.10-1.020.130.024
Wine, one glass a day4.210.232.355.87<0.001
IADL0.270.130.070.460.011

Ferritinc
Female-0.48-0.21-0.720.23<0.001
Living in nursing home-0.61-0.25-0.84-0.34<0.001
Edentulism-0.03-0.08-0.700.000.011
Chronic diseases, more than 3-0.01-0.01-0.280.020.005
Fruit/vegetable servings0.01-0.01-0.020.060.028
BMI0.010.070.000.020.015

Haemoglobind
Female-12.95-0.37-15.45--9.85<0.001
Age-3.91-0.10-7.14-0.680.011
Number of medications, more than 3-0.83-0.01-1.39-0.260.004
Wine, one glass a day6.530.011.6211.440.037
Mobility-0.31-0.20-0.54-0.110.003
BMI0.170.150.070.260.003
Total cholesterole
Fruit/vegetable servings1.560.010.501.930.031

Female0.400.170.190.60<0.001
Age-0.16-0.06-0.410.080.016
Drinking sweetened drinks, >20.070.080.000.140.024
Whole milk consumption0.280.160.120.44<0.001
Balance0.030.320.200.40<0.001
DOI: https://doi.org/10.2478/sjph-2021-0006 | Journal eISSN: 1854-2476 | Journal ISSN: 0351-0026
Language: English
Page range: 30 - 37
Submitted on: Nov 11, 2019
|
Accepted on: Nov 19, 2020
|
Published on: Dec 31, 2020
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 Jelena Pavlović, Maja Račić, Nedeljka Ivković, published by National Institute of Public Health, Slovenia
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.