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Screening strategy modification based on personalized breast cancer risk stratification and its implementation in the national guidelines – pilot study Cover

Screening strategy modification based on personalized breast cancer risk stratification and its implementation in the national guidelines – pilot study

Open Access
|Oct 2020

Figures & Tables

Table 1

The summary of criteria for the higher risk women category and advised breast cancer screening tests according to current Rules on Carrying Out Preventive Health Care at the Primary Level (5).

Criteria for higher breast cancer risk category
(at least one of the following)
Screening tests at a Breast Unit for the higher breast cancer risk category
(after the age of 40)
Personal history of breast cancer in the past
Table 2

Characteristics of the studied women according to breast cancer risk factors.

Number of womenPercent (%)
Age groups
20-39 years8744.2
40-49 years10452.8
50-59 years63.0
Family history
positive6231.5
negative13568.5
Age at menarche
<11 years73.6
11-12 years5728.9
13-14 years10854.8
>15 years2512.7
Age at first full-term birth
<25 years8141.1
25-29 years5427.4
>30 years3115.7
nulliparous3115.7
Table 3

Breast cancer risk categories for Slovenian women.

Low risk
(%)
Population risk
(%)
Moderately increased
risk (%)
High risk
(%)
Lifetime risk between ages 20 and 39-<1616 and higher>30
10-year risk between ages 40 and 49-<2.02.0 to 6.5>6.5
10-year risk between ages 50 and 59<1.31.3 to<4.04.0 to 6.5>6.5
10-year risk from age 60+<1.31.3 to<5.55.5 to 6.5>6.5
Table 4

Comparison of anticipated mammographic screening and screening foreseen in the new Slovenian guidelines by breast cancer risk categories and age groups.

Breast cancer risk category*Population riskModerately increased riskPopulation riskModerately increased risk
Ages between 20 and 395400
Ages between 40 and 494327034
Ages between 50 and 551-6-
All ages4931634

* Risk category was determined by S-IBIS calculation, and division into risk groups was performed as proposed in Table 3.

Table 5

Comparison of anticipated ultrasound screening for breast cancer prevention and screening foreseen in the new Slovenian guidelines by breast cancer risk categories and age groups.

Breast cancer risk category*Population riskModerately increased riskPopulation riskModerately increased risk
Ages between 20 and 3973According to the new guidelines ultrasound screening is recommended only upon referral from a radiologist
Ages between 40 and 49149
Ages between 50 and 550-
All ages2112

* Risk category was determined by S-IBIS calculation, and division into risk groups was performed as proposed in Table 3.

DOI: https://doi.org/10.2478/sjph-2020-0027 | Journal eISSN: 1854-2476 | Journal ISSN: 0351-0026
Language: English, Slovenian
Page range: 211 - 218
Submitted on: Mar 24, 2020
Accepted on: Aug 31, 2020
Published on: Oct 18, 2020
Published by: National Institute of Public Health, Slovenia
In partnership with: Paradigm Publishing Services

© 2020 Mateja Krajc, D Gareth Evans, Ana Blatnik, Katarina Lokar, Tina Žagar, Sonja Tomšič, Janez Žgajnar, Vesna Zadnik, published by National Institute of Public Health, Slovenia
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.