Figure 1

Figure 2

Figure 3

Estimated means of mTPB indicators - between-level analysis of variance_
| 95% CI | ||||
|---|---|---|---|---|
| Indicator and time point | Mean | SE | L | U |
| NS | ||||
| End of treatment | 66.5 | 1.68 | 63.2 | 69.8 |
| 5-year follow-up | 62.7 | 1.68 | 59.4 | 66.0 |
| 10-year follow-up | 60.7 | 2.63 | 55.5 | 65.9 |
| 18-year follow-up | 61.0 | 2.93 | 55.2 | 66.7 |
| ND | ||||
| End of treatment | 47.2 | 1.38 | 44.4 | 49.9 |
| 5-year follow-up | 45.4 | 1.38 | 42.7 | 48.1 |
| 10-year follow-up | 49.7 | 2.16 | 45.4 | 54.0 |
| 18-year follow-up | 50.2 | 2.40 | 45.5 | 55.0 |
| UT | ||||
| End of treatment | 42.2 | 2.14 | 37.9 | 46.4 |
| 5-year follow-up | 30.5 | 2.14 | 26.3 | 34.7 |
| 10-year follow-up | 26.8 | 3.36 | 20.1 | 33.4 |
| 18-year follow-up | 28.4 | 3.74 | 21.0 | 35.8 |
| BE | ||||
| End of treatment | 48.4 | 1.11 | 46.2 | 50.6 |
| 5-year follow-up | 48.4 | 1.11 | 46.2 | 50.6 |
| 10-year follow-up | 63.7 | 1.75 | 60.2 | 67.1 |
| 18-year follow-up | 59.3 | 1.94 | 55.4 | 63.1 |
| BI | ||||
| End of treatment | 8.6 | 0.53 | 7.5 | 9.6 |
| 5-year follow-up | 8.6 | 0.53 | 7.5 | 9.6 |
| 10-year follow-up | 9.1 | 0.83 | 7.5 | 10.7 |
| 18-year follow-up | 8.1 | 0.92 | 6.3 | 9.9 |
Within-subject model characteristics – Greenhouse- Geisser correction of repeated measures ANOVA_
| Indicator | df | df(error) | Exact F | p-value | Eta2 |
|---|---|---|---|---|---|
| NS | 2.508 | 37.615 | 2.882 | 0.057 | 0.161 |
| ND | 2.813 | 42.192 | 0.593 | 0.612 | 0.038 |
| UT | 1.986 | 29.790 | 3.819 | 0.034 | 0.203 |
| BE | 1.921 | 28.820 | 15.938 | <0.001 | 0.515 |
| BI | 1.894 | 28.405 | 0.385 | 0.673 | 0.025 |
Significant and marginally significant pairwise comparisons of within-subject differences – repeated measures ANOVA_
| Indicator | Difference | Mean Difference | Std. Error | p-value | 95% CI | |
|---|---|---|---|---|---|---|
| L | U | |||||
| UT | 3 - 1 | -12.938 | 4.270 | 0.051 | -25.901 | 0.026 |
| 4 - 1 | -11.688 | 3.874 | 0.052 | -23.449 | 0.074 | |
| BE | 3 - 1 | 15.250 | 2.980 | 0.001 | 6.203 | 24.297 |
| 4 - 1 | 11.375 | 2.729 | 0.005 | 3.088 | 19.662 | |
| 3 - 2 | 15.250 | 2.980 | 0.001 | 6.203 | 24.297 | |
| 4 - 2 | 11.375 | 2.729 | 0.005 | 3.088 | 19.662 | |
