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Influence of Atrial Fibrillation on Two-Year Survival of Patients with Implanted Cardioverter Defibrillator Cover

Influence of Atrial Fibrillation on Two-Year Survival of Patients with Implanted Cardioverter Defibrillator

EABR. Experimental and Applied Biomedical Research
Volume 25 (2024): Issue 3 (September 2024)
By: Vladimir Ignjatović,  Ivana Đokić-Nikolić,  Stefan Simović,  Bojana Đoković,  Ema Jevtić,  Zorica Smiljanić and  Vesna Ignjatović  
Open Access
|Nov 2022
Figures & tables

Figures & Tables

Figure 1.

Patient survival curves.

Figure 2.

Types of activation of the implanted cardioverter defibrillator.

Distribution of types ICD activation between the groups_

GroupSinus rhythmAtrial fibrillationP
Incidence of appropriate ICD activation16 (48.5%)17 (51,5%)p=0.863b
Incidence of inappropriate ICD activation3 (21,4%)11 (78,6%)P=0.046b*

Demographic characteristics of patient groups

GroupSinus rhythmAtrial fibrillationp
Number(%)99 (47,1%)111 (52,9%)
Age (years)67,7 ± 11,367,7 ± 9,6p=0,517a
GenderMan68 (68,7%)78(70,3%)p=0.062b
Woman31 (31,3%)33 (29,7%)
Hypertension77,8%88,3%p=0.064b
Diabetes mellitus41,4%28,8%p=0.056b
Hyperlipidemia65,6%60,0%p=0.399b
Smoking27,3%21,6%p=0.340b
Heredity27,2%21,6%p=0.340b

Prevalence of cardiovascular drug groups in patient groups_

GroupSinus rhythmAtrial fibrillationp
Amiodarone49.5%68.5%p=0.005b*
Beta blocker84.5%91.0%p=0.154b
ACE inhibitor74.7%71.2%p=0.481b
Anticoagulant therapy61.0%95.5%p=0.000b*
ASA56.1%25.2%p=0.000b*
Thienopyridine19.1%9.0%p=0.028b*
Statin67.7%58.6%p=0.143b

Distribution of patients with ICD activation between the compared groups_

GroupSinus rhythmAtrial fibrillationp
Number of patients with ICD activation16 (16.2%)23 (20.7%)P=0.396b

Prevalence of associated cardiovascular diseases_

GroupSinus rhythmAtrial fibrillationp
Ischemic heart disease60.6%35.1%p=0.000b*
Non-ischemic heart disease39.4%64.9%
Peripheral artery disease21.2%9.9%p=0.023b*
Cerebrovascular event5.0%14.4%p=0.024b*
Chronic renal failure7.1%10.8%p=0.346b

Value of laboratory parameters between compared groups

GroupSinus rhythmAtrial fibrillationp
NT-proBNP (pg/mL)Mean ± SD4037.5 ± 5474.54852.3 ± 6645.1p=0.177c
Median1519.52036
Troponin (pg/mL)Mean ± SD0.065 ± 0.1380.065±0.20p=0.978c
Median0.0190.019
Hemoglobin (g/L)Mean ± SD125.1 ± 18.5129.4 ± 22.9p=0.113c
Median129132
CRP (mg/L)Mean ± SD8.39 ± 12.288.33 ± 10.8p=0.815c
Median4.954.20
Urea (mmol/L)Mean ± SD9.00 ± 4.018.38 ± 4.25p=0.362c
Median8.157.6
Creatinine (µmol/L)Mean ± SD125.9 ± 157.5114.1 ± 52.0p=0.104c
Median96104
Na+ (mmol/L)Mean ± SD139.6 ± 3.8135.42 ±14.25p=0.794c
Median140140
DOI: https://doi.org/10.2478/sjecr-2022-0035 | Journal eISSN: 2956-2090 | Journal ISSN: 2956-0454
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Language: English
Page range: 259 - 266
Submitted on: Feb 5, 2022
Accepted on: Feb 19, 2022
Published on: Nov 23, 2022
Published by: University of Kragujevac, Faculty of Medical Sciences
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
Atrial fibrillation,
implantable cardioverter defibrillator,
ICD,
heart failure,
sudden cardiac death
Related subjects:
Medicine,
Clinical medicine,
Clinical medicine, other

© 2022 Vladimir Ignjatović, Ivana Đokić-Nikolić, Stefan Simović, Bojana Đoković, Ema Jevtić, Zorica Smiljanić, Vesna Ignjatović, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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