The effects of Antidepressant Therapy on Health-Related Quality of Life in Patients with a Chronic Obstructive Pulmonary Disease and Depressive Symptoms

Variable		Values
Age (years)		48.84±7.43
Gender (male)		30 (34.5%)
FEV₁ (%)		74.79±15.07
mMRC	Stage 1	34 (39.1%)
	Stage 2	43 (49.4%)
	Stage 3	10 (11.5%)
HAM-D scale score before SSRIs therapy		15.79±4.43	Related samples Wilcoxon signed rank test p<0.001
HAM-D scale score after 8 weeks of SSRIs therapy		10.02±3.97	Related samples Wilcoxon signed rank test p<0.001
Q-LES-Q-SF score before AD		32.43±5.51	Related samples Wilcoxon signed rank test p<0.001
Q-LES-Q-SF score after AD		46.65±4.79	Related samples Wilcoxon signed rank test p<0.001
Difference in Q-LES-Q-SF score (after – before)		14.20 ± 2.02

Significant predictor of difference between values of the Q-LES-Q-SF score after and before the treatment with SSRIs.

Predictor	Adjusted R²	F	B	t	p	95,0% Confidence Interval for B
Predictor	Adjusted R²	F	B	t	p	Lower Bound	Upper Bound
FEV₁	0.051	5.625 (p=0.020)	−0.034	−2.372	0.020	−0.062	−0.005

DOI: https://doi.org/10.2478/sjecr-2021-0068 | Journal eISSN: 2956-2090 (formerly 2335-075X, 2956-0454) | Journal ISSN: 2956-0454 (formerly 1820-8665)

Language: English

Page range: 243 - 248

Submitted on: Nov 18, 2021

Accepted on: Dec 19, 2021

Published on: Jan 17, 2022

Published by: University of Kragujevac, Faculty of Medical Sciences

In partnership with: Paradigm Publishing Services

Keywords:

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© 2022 Ivana Jelic, Marko Folic, Filip Mihajlovic, Slobodan Jankovic, Goran Mihajlovic, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.