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The effects of Antidepressant Therapy on Health-Related Quality of Life in Patients with a Chronic Obstructive Pulmonary Disease and Depressive Symptoms

Open Access
|Jan 2022

Figures & Tables

Characteristics of the study (n=87) group, and main outcomes_

VariableValues
Age (years)48.84±7.43
Gender (male)30 (34.5%)
FEV1 (%)74.79±15.07
mMRCStage 134 (39.1%)
Stage 243 (49.4%)
Stage 310 (11.5%)
HAM-D scale score before SSRIs therapy15.79±4.43Related samples Wilcoxon signed rank test p<0.001
HAM-D scale score after 8 weeks of SSRIs therapy10.02±3.97
Q-LES-Q-SF score before AD32.43±5.51Related samples Wilcoxon signed rank test p<0.001
Q-LES-Q-SF score after AD46.65±4.79
Difference in Q-LES-Q-SF score (after – before)14.20 ± 2.02

Significant predictor of difference between values of the Q-LES-Q-SF score after and before the treatment with SSRIs_

PredictorAdjusted R2FBtp95,0% Confidence Interval for B
Lower BoundUpper Bound
FEV10.0515.625 (p=0.020)−0.034−2.3720.020−0.062−0.005
DOI: https://doi.org/10.2478/sjecr-2021-0068 | Journal eISSN: 2956-2090 | Journal ISSN: 2956-0454
Language: English
Page range: 243 - 248
Submitted on: Nov 18, 2021
Accepted on: Dec 19, 2021
Published on: Jan 17, 2022
Published by: University of Kragujevac, Faculty of Medical Sciences
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2022 Ivana Jelic, Marko Folic, Filip Mihajlovic, Slobodan Jankovic, Goran Mihajlovic, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.