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Antioxidant Supplementation with N-Acetylcysteine as a Protection Against Cisplatin-Induced Motor Impairment in Rats

Open Access
|Sep 2022

References

  1. 1. Rosenberg B, Vancamp L, Krigas T. Inhibition of cell division in escherichia coli by electrolysis products from a platinum electrode. Nature. 1965;205:698-99.10.1038/205698a014287410
  2. 2. Kelland L. The resurgence of platinum-based cancer chemotherapy. Nat Rev Cancer. 2007;7(8):573-584.10.1038/nrc216717625587
  3. 3. Manohar S, Leung N. Cisplatin nephrotoxicity: a review of the literature. J Nephrol. 2018;31(1):15-25.10.1007/s40620-017-0392-z28382507
  4. 4. Pınar N, Çakırca G, Hakverdi S, Kaplan M. Protective effect of alpha lipoic acid on cisplatin induced hepatotoxicity in rats. Biotech Histochem. 2020;95(3):219-224.10.1080/10520295.2019.166702531687838
  5. 5. Carozzi VA, Canta A, Chiorazzi A. Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms? Neurosci Lett. 2015;596:90-107.
  6. 6. Chiorazzi A, Semperboni S, Marmiroli P. Current View in Platinum Drug Mechanisms of Peripheral Neurotoxicity. Toxics. 2015;3(3):304-321.10.3390/toxics3030304560668229051466
  7. 7. Santabarbara G, Maione P, Rossi A, Gridelli C. Pharmacotherapeutic options for treating adverse effects of Cisplatin chemotherapy. Expert Opin Pharmacother. 2016;17(4):561-570.10.1517/14656566.2016.112275726581586
  8. 8. Abdelkader NF, Saad MA, Abdelsalam RM. Neuroprotective effect of nebivolol against cisplatin-associated depressive-like behavior in rats. J Neurochem. 2017;141(3):449-460.10.1111/jnc.1397828178754
  9. 9. Dean OM, Bush AI, Berk M. Translating the Rosetta Stone of N-acetylcysteine. Biol Psychiatry. 2012;71(11):935-936.10.1016/j.biopsych.2012.04.00122579303
  10. 10. Hamm RJ, Pike BR, O'Dell DM, Lyeth BG, Jenkins LW. The rotarod test: an evaluation of its effectiveness in assessing motor deficits following traumatic brain injury. J Neurotrauma. 1994;11(2):187-196.10.1089/neu.1994.11.1877932797
  11. 11. Deacon RM. Measuring motor coordination in mice. J Vis Exp. 2013;(75):e2609.10.3791/2609372456223748408
  12. 12. Prut L, Belzung C. The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review. Eur J Pharmacol. 2003;463(1-3):3-33.10.1016/S0014-2999(03)01272-X
  13. 13. Rodgers RJ, Dalvi A. Anxiety, defence and the elevated plus-maze. Neurosci Biobehav Rev. 1997;21(6):801-810.10.1016/S0149-7634(96)00058-9
  14. 14. Crawley JN. Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests. Brain Res. 1999;835(1):18-26.10.1016/S0006-8993(98)01258-X10448192
  15. 15. Chen J, Li Y, Wang L, et al. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke. 2001;32(4):1005-1011.10.1161/01.STR.32.4.1005
  16. 16. Ohlsson AL, Johansson BB. Environment influences functional outcome of cerebral infarction in rats. Stroke. 1995;26(4):644-649.10.1161/01.STR.26.4.644
  17. 17. Golchin L, Shabani M, Harandi S, Razavinasab M. Pistachio supplementation attenuates motor and cognition impairments induced by cisplatin or vincristine in rats. Adv Biomed Res. 2015;4:92.10.4103/2277-9175.156656443448726015918
  18. 18. Dickey DT, Wu YJ, Muldoon LL, Neuwelt EA. Protection against cisplatin-induced toxicities by N-acetycy-steine and sodium thiosulfate as assessed at the molecular, cellular, and in vivo levels. J Pharmacol Exp Ther. 2005;314(3):1052-1058.10.1124/jpet.105.08760115951398
  19. 19. Rosic G, Srejovic I, Zivkovic V, Selakovic D, Joksimovic J, Jakovljevic V. The effects of N-acetylcysteine on cisplatin-induced cardiotoxicity on isolated rat hearts after short-term global ischemia. Toxicol Rep. 2015;2:996-1006.10.1016/j.toxrep.2015.07.009559838228962440
  20. 20. Rosic G, Selakovic D, Joksimovic J, et al. The effects of N-acetylcysteine on cisplatin-induced changes of cardiodynamic parameters within coronary autoregulation range in isolated rat hearts. Toxicol Lett. 2016;242:34-46.10.1016/j.toxlet.2015.11.02826656795
  21. 21. Kumburovic I, Selakovic D, Juric T, et al. Antioxidant Effects of Satureja hortensis L. Attenuate the Anxiogenic Effect of Cisplatin in Rats. Oxid Med Cell Longev. 2019;2019:8307196.10.1155/2019/8307196670130531467638
  22. 22. Ennaceur A, Chazot PL. Preclinical animal anxiety research - flaws and prejudices. Pharmacol Res Perspect. 2016;4(2):e00223.10.1002/prp2.223480432427069634
  23. 23. Shabani M, Nazeri M, Parsania S, et al. Walnut consumption protects rats against cisplatin-induced neurotoxicity. Neurotoxicology. 2012;33(5):1314-1321.10.1016/j.neuro.2012.08.00422935099
  24. 24. Wu CT, Liao JM, Ko JL, et al. D-Methionine Ameliorates Cisplatin-Induced Muscle Atrophy via Inhibition of Muscle Degradation Pathway. Integr Cancer Ther. 2019;18:1534735419828832.
  25. 25. Balik MS, Tumkaya L, Mercantepe T, Yilmaz A, Balik G, Topcu A, Yazici Z. Protective Effect of TeaGrape Extract on Cisplatin-Induced Muscle Atrophy: A Morphological Study. Iran Red Crescent Med J. 2018;20(9): e66319.10.5812/ircmj.66319
  26. 26. Ates B, Vardi N, Parlakpinar H, Karaaslan MG, Yilmaz I, Ercal N. The Protective Effect of N-Acetylcysteine Amide Against Paraquat-Induced Neurotoxicity. Turk J Chem. 2019;43(1): 39-49.10.3906/kim-1706-8
  27. 27. Wright DJ, Renoir T, Smith ZM, et al. N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease. Transl Psychiatry. 2015;5(1):e492.10.1038/tp.2014.131431282625562842
  28. 28. Owoeye O, Onwuka SK. Tomato pomace powder ameliorated cisplatin-induced microanatomical alterations in brain of Wistar rats. Int J Biol Chem Sci. 2015;9(1): 1-11.10.4314/ijbcs.v9i1.1
DOI: https://doi.org/10.2478/sjecr-2019-0076 | Journal eISSN: 2956-2090 | Journal ISSN: 2956-0454
Language: English
Page range: 261 - 267
Submitted on: Dec 12, 2019
Accepted on: Dec 18, 2019
Published on: Sep 20, 2022
Published by: University of Kragujevac, Faculty of Medical Sciences
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2022 Rade Vukovic, Igor Kumburovic, Nemanja Jovicic, Stefan Velickovic, Aleksandra Arnaut, Dragica Selakovic, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.