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Comparison of Thyroglobulin Concentrations Measured by Two Immunoradiometric Assay Cover

Comparison of Thyroglobulin Concentrations Measured by Two Immunoradiometric Assay

Open Access
|Aug 2020

Abstract

Circulating thyroglobulin measurements is a highly specific test in the management of patients affected by differentiated thyroid cancer after total thyroidectomy, followed by radioiodine ablation. The aim of our study was to compare two thyroglobulinimmunoradiometric assays (INEP, Serbia and Cisbio Bioassays, France). Study included 42 patients of both genders with DTC. The subjects were on suppres¬sive doses of levothyroxine and followed up. Results showed concordance between the two assay methods for determining serum thyroglobulin for 39 (92.85%) patients. Statistical analysis showed that there was a direct correlation between two IRMA tests, with a positive correlation coefficient r=0.613 (p 0.05). We concluded that there is good agreement between the two thyroglobulin assays compared in this study.

DOI: https://doi.org/10.2478/sjecr-2018-0031 | Journal eISSN: 2956-2090 | Journal ISSN: 2956-0454
Language: English
Page range: 121 - 125
Submitted on: Feb 27, 2018
Accepted on: Apr 18, 2018
Published on: Aug 27, 2020
Published by: University of Kragujevac, Faculty of Medical Sciences
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 Vesna Ignjatovic, Milovan Matovic, Vladimir Vukomanovic, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.