Skip to main content
Have a personal or library account? Click to login
Unfolded Protein Response Is Activated in the Hearts of Catecholaminergic Polymorphic Ventricular Tachycardia (Cpvt) Mice Cover

Unfolded Protein Response Is Activated in the Hearts of Catecholaminergic Polymorphic Ventricular Tachycardia (Cpvt) Mice

EABR. Experimental and Applied Biomedical Research
Volume 15 (2014): Issue 3 (September 2014)
By:   
Open Access
|Oct 2014
References

References

  1. 1. Myerburg RJ, Conde CA, Castellanos A. Survivors of prehospital cardiac arrest. JAMA 1982; 247: 1485-90.
    Open DOISearch in Google Scholar
  2. 2. Zipes DP, Camm AJ, Borggrefe M, Buxton AE et al. American College of Cardiology/American Heart Association Task Force; European Society of Cardiology Committee for Practice Guidelines; European Heart Rhythm Association; Heart Rhythm Society. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: A report of the American College of Cardiology/American Heart Association Task Force and theEuropean Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) Developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Circulation 2006; 114: 385-84.
    Search in Google Scholar
  3. 3. Priori SG, Napolitano C, Tiso N, Memmi M, Vignati G, Bloise R, Sorrentino V, Danieli GA. Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia. Circulation 2001; 103: 196-200.
    Open DOISearch in Google Scholar
  4. 4. Brunello L, Slabaugh JL, Radwanski PB et al. Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia. Proc Natl Acad Sci U S A. 2013;110(25): 10312-17.
    Open DOISearch in Google Scholar
  5. 5. Eldar M, Pras E, Lahat H. A missense mutation in the CASQ2 gene is associated with autosomal-recessive catecholamine-induced polymorphic ventricular tachycardia. Trends Cardiovasc Med 2003; 13: 148-51.
    Open DOISearch in Google Scholar
  6. 6. Napolitano C, Priori SG. Diagnosis and treatment of catecholaminergic polymorphic ventricular tachycardia. Heart Rhythm 2007; 4: 675-78.
    Open DOISearch in Google Scholar
  7. 7. Song L, Alcalai R, Arad M, Wolf CM, Toka O, Conner DA, Berul CI, Eldar M, Seidman CE, Seidman JG. Calsequestrin 2 (CASQ2) mutations increase axpression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia. J Clin Inv 2007; 17: 1814-23.
    Open DOISearch in Google Scholar
  8. 8. Cerrone M, Colombi B, Santoro M et al. Bidirectional Ventricular Tachycardia and Fibrillation Elicited in a Knock-In Mouse Model Carrier of a Mutation in the Cardiac Ryanodine Receptor. Circ Res 2005; 96: e77-82.
    Open DOISearch in Google Scholar
  9. 9. Rizzi N, Liu N, Napolitano C et al. Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model. Circ Res 2008; 13: 298-306. DOI: 10.1161/ CIRCRESAHA.108.171660.
    Open DOISearch in Google Scholar
  10. 10. Flucher BE, Franzini-Armstrong C. Formation of junctions involved in excitation-contraction coupling in skeletal and cardiac muscle. Proc Natl Acad Sci USA 1996; 93: 8101-06.
    Open DOISearch in Google Scholar
  11. 11. Beard NA, Laver DR, Dulhunty AF. Calsequestrin and the calcium release channel of skeletal and cardiac muscle. Prog Biophys Mol Biol 2004; 85: 33-69.
    Open DOISearch in Google Scholar
  12. 12. Beard NA, Wei L, Dulhunty AF. Ca(2+) signaling in striated muscle: the elusive roles of triadin, junctin, and calsequestrin. Eur. Biophys. J. 2009; 39: 27-36. DOI: 10.1007/s00249-009-0449-6.
    Open DOISearch in Google Scholar
  13. 13. Beard NA, Casarotto MG, Wei L, Varsanyi M, Laver DR, Dulhunty AF. Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca2+ and phosphorylation. and phosphorylation. Biophys J 2005; 88: 3444-54.
    Open DOISearch in Google Scholar
  14. 14. Tijskens P, Jones LR, Franzini-Armstrong C. Junctin and calsequestrin overexpression in cardiac muscle: the role of junctin and the synthetic and delivery pathways for the two proteins. J Mol Cell Cardiol 2003; 35: 961-74.
    Open DOISearch in Google Scholar
  15. 15. Catterall WA. Structure and regulation of voltage-gated Ca2+ channels. Annu. Rev. Cell. Dev. Biol. 2000; 16: 521-55.
    Search in Google Scholar
  16. 16. Terentyev D, Nori A, Santoro M, Viatchenko-Karpinski S et al. Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death. Circ Res 2006; 98: 1151-58.
    Open DOISearch in Google Scholar
  17. 17. Kirchhefer U, Wehrmeister D, Postma AV, Pohlentz G, Mormann M, Kucerova D, Muller FU, Schmitz W, Schulze-Bahr E, Wilde AA, Neumann J. The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling. J Mol Cell Cardiol 2010; 49: 95-105. DOI: 10.1016/j. yjmcc.2010.03.006.
    Search in Google Scholar
  18. 18. di Barletta MR, Viatchenko-Karpinski S, Nori A, Memmi M, Terentyev D, Turcato F, Valle G, Rizzi N, Napolitano C, Gyorke S, Volpe P, Priori SG. Clinical phenotype and functional characterization of CASQ2 mutations associated with Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation 2006; 114: 1012-19.
    Open DOISearch in Google Scholar
  19. 19. Chopra N, Yang T, Asghari P, Moore ED et al. Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias. Proc Natl Acad Sci USA 2009; 106: 7636-41. DOI: 10.1073/pnas.0902919106.
    Open DOISearch in Google Scholar
  20. 20. Groenendyk J, Sreenivasaiah PK, Kim do H, Agellon LB, Michalak M. Biology of endoplasmic reticulum stress in the heart. Circ Res 2010; 107: 1185-97. DOI: 10.1161/CIRCRESAHA.110.227033.
    Open DOISearch in Google Scholar
  21. 21. Glembotski C. Endoplasmic reticulum stress in the heart. Circ. Res 2007; 101: 975-84.
    Open DOISearch in Google Scholar
  22. 22. Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol 2002; 2: 326-32.
    Open DOISearch in Google Scholar
  23. 23. Brodsky JL. The protective and destructive roles played by molecular chaperones during ERAD (endoplasmicreticulum- associated degradation). Biochem J 2007; 404: 353-63.
    Open DOISearch in Google Scholar
  24. 24. Maattanen P, Gehring K, Bergeron JJ, Thomas DY. Protein quality control in the ER: the recognition of misfolded proteins. Semin Cell Dev Biol 2010; 21: 500-511. DOI: 10.1016/j.semcdb.2010.03.006.
    Open DOISearch in Google Scholar
  25. 25. Bernales, S., McDonald, K.L. and Walter, P. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol 2006; 4: 423.
    Open DOISearch in Google Scholar
  26. 26. Glembotski C. The role of the unfolded protein response in the heart. J Mol Cell Card 2007; 44: 453-59.
    Open DOISearch in Google Scholar
  27. 27. Gustafsson AB. Bnip3 as a dual regulator of mitochondrial turnover and cell death in the myocardium. Pediatr Cardiol 2011; 32: 267-274. DOI: 10.1007/s00246-010-9876-5.
    Open DOISearch in Google Scholar
  28. 28. Lee JW, Kim WH, Yeo J Jung MH. ER stress is implicated in mitochondrial dysfunction-induced apoptosis of pancreatic beta cells. Mol Cells 2010; 30: 545-549. DOI: 10.1007/s10059-010-0161-5.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.2478/sjecr-2014-0016 | Journal eISSN: 2956-2090 (formerly 2335-075X, 2956-0454) | Journal ISSN: 2956-0454 (formerly 1820-8665)
Journal RSS Feed
Language: English, Croatian, Slovenian
Page range: 121 - 127
Submitted on: Apr 8, 2014
Accepted on: Aug 12, 2014
Published on: Oct 10, 2014
Published by: University of Kragujevac, Faculty of Medical Sciences
In partnership with: Paradigm Publishing Services
Keywords:
Calsequestrin,
CPVT,
ERAD,
UPR,
Triadin,
Chaperones
Related subjects:
Medicine,
Clinical medicine,
Clinical medicine, other

© 2014 Rigers Bakiu, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 15 (2014): Issue 3 (September 2014)
Previous article
Next article