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Value of serum NT-IGFBP-4 for non-invasive risk stratification of coronary heart disease and predictive efficiency for complexity of coronary artery lesions Cover

Value of serum NT-IGFBP-4 for non-invasive risk stratification of coronary heart disease and predictive efficiency for complexity of coronary artery lesions

Open Access
|Aug 2025

References

  1. Duggan JP, Peters AS, Trachiotis GD, Antevil JL. Epidemiology of Coronary Artery Disease. Surg Clin North Am. 2022;102(3):499-516. DOI: 10.1016/j.suc.2022.01.007
  2. Shaya GE, Leucker TM, Jones SR, Martin SS, Toth PP. Coronary heart disease risk: Low-density lipoprotein and beyond. Trends Cardiovasc Med. 2022;32(4):181-94. DOI: 10.1016/j.tcm.2021.04.002
  3. Mortensen MB, Dzaye O, Bøtker HE, Jensen JM, Maeng M, Bentzon JF, et al. Low-Density Lipoprotein Cholesterol Is Predominantly Associated With Atherosclerotic Cardiovascular Disease Events in Patients With Evidence of Coronary Atherosclerosis: The Western Denmark Heart Registry. Circulation. 2023;147(14):1053-63. DOI: 10.1161/CIRCULATIONAHA.122.061010
  4. Kwiecinski J, Tzolos E, Williams MC, Dey D, Berman D, Slomka P, et al. Noninvasive Coronary Atherosclerotic Plaque Imaging. JACC Cardiovasc Imaging. 2023;16(12):1608-22. DOI: 10.1016/j.jcmg.2023.08.021
  5. In China TWCOTROCHAD, Hu SS. Report on cardiovascular health and diseases in China 2021: an updated summary. J Geriatr Cardiol. 2023;20(6):399-430. DOI: 10.26599/1671-5411.2023.06.001
  6. Yang T, Liu Y, Li L, Zheng Y, Wang Y, Su J, et al. Correlation between the triglyceride-to-high-density lipoprotein cholesterol ratio and other unconventional lipid parameters with the risk of prediabetes and Type 2 diabetes in patients with coronary heart disease: a RCSCD-TCM study in China. Cardiovasc Diabetol. 2022;21(1):93. DOI: 10.1186/s12933-022-01531-7
  7. Lu X, Liu Z, Cui Q, Liu F, Li J, Niu X, et al. A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study. Eur Heart J. 2022;43(18):1702-11. DOI: 10.1093/eurheartj/ehac093
  8. Adasheva DA, Lebedeva OS, Goliusova DV, Postnikov AB, Teriakova MV, Kopylova IV, et al. PAPP-A-specific IGFBP-4 proteolysis in human induced pluripotent stem cell-derived cardiomyocytes. Int J Mol Sci. 2023;24(9):8420. DOI: 10.3390/ijms24098420
  9. Hjortebjerg R, Lindberg S, Pedersen S, Mogelvang R, Jensen JS, Oxvig C, et al. Insulin-like growth factor binding protein 4 fragments provide incremental prognostic information on cardiovascular events in patients with ST-segment elevation myocardial infarction. J Am Heart Assoc. 2017;6(3):e005358. DOI: 10.1161/JAHA.116.005358
  10. Ndrepepa G. SYNTAX Score and Outcomes in Complex Coronary Artery Disease After Percutaneous Coronary Intervention: Is the Use of Intravascular Ultrasound an Equalizer of Disease Severity? Am J Cardiol. 2023;206:345-6. DOI: 10.1016/j.amjcard.2023.08.150
  11. Serruys PW, Revaiah PC. Leveraging QFR and SYNTAX score II 2020 to guide PCI versus CABG decisions in multivessel CAD -broadening QFR’s utility. EuroIntervention. 2024;20(9):518-20. DOI: 10.4244/EIJ-E-24-00024
  12. Guo J, Wang H, Li Y, Zhu S, Hu H, Gu Z. Nanotechnology in coronary heart disease. Acta Biomater. 2023;171:37-67. DOI: 10.1016/j.actbio.2023.09.011
  13. Shaikh A, Khan SD, Baloch F, Virani SS, Samad Z. The COVID-19 Pandemic and Coronary Heart Disease: the Next Surge. Curr Atheroscler Rep. 2023;25(9):559-69. DOI: 10.1007/s11883-023-01131-0
  14. Boakye E, Grandhi GR, Dardari Z, Adhikari R, Soroosh G, Jha K, et al. Cardiovascular risk stratification among individuals with obesity: The Coronary Artery Calcium Consortium. Obesity. 2023;31(9):2240-8. DOI: 10.1002/oby.23832
  15. Awasthi S, Sachdeva N, Gupta Y, Anto AG, Asfahan S, Abbou R, et al. Identification and risk stratification of coronary disease by artificial intelligence-enabled ECG. EClinicalMedicine. 2023;65:102259. DOI: 10.1016/j.eclinm.2023.102259
  16. Razavi AC, Uddin SMI, Dardari ZA, Berman DS, Budoff MJ, Miedema MD, et al. Coronary Artery Calcium for Risk Stratification of Sudden Cardiac Death: The Coronary Artery Calcium Consortium. JACC Cardiovasc Imaging. 2022;15(7):1259-70. DOI: 10.1016/j.jcmg.2022.02.011
  17. Scala A, Erriquez A, Verardi FM, Marrone A, Scollo E, Trichilo M, et al. Functional (Re)Development of SYNTAX Score II 2020: Predictive Performance and Risk Assessment. J Clin Med. 2023;12(18):5844. DOI: 10.3390/jcm12185844
  18. Etman W, Loutfi M, Ahmed K, Eltahan S, Rayan A. Outcome of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting for Patients With Intermediate SYNTAX II Score. Curr Probl Cardiol. 2023;48(2):101512. DOI: 10.1016/j.cpcardiol.2022.101512
  19. Medranda GA, Faraz HA, Thompson JB, Zhang Y, Bharadwaj AS, Osborn EA, et al. Association of Preprocedural SYNTAX Score With Outcomes in Impella-Assisted High-Risk Percutaneous Coronary Intervention. J Soc Cardiovasc Angiogr Interv. 2024;3(8):101981. DOI: 10.1016/j.jscai.2024.101981
  20. Bhattarai A, Singh Sunar P, Shah S, Chamlagain R, Babu Pokhrel N, Khanal P, et al. CT-IGFBP-4 as a Predictive Novel Biomarker of Ischemic Cardiovascular Events and Mortality: A Systematic Review. J Interv Cardiol. 2022;2022:1816504. DOI: 10.1155/2022/1816504
  21. Kageyama S, Serruys PW, Kotoku N, Garg S, Ninomiya K, Masuda S, et al. Coronary computed tomography angiography-based SYNTAX score for comprehensive assessment of advanced coronary artery disease. J Cardiovasc Comput Tomogr. 2024;18(2):120-36. DOI: 10.1016/j.jcct.2023.10.012
DOI: https://doi.org/10.2478/rrlm-2025-0016 | Journal eISSN: 2284-5623 | Journal ISSN: 1841-6624
Language: English
Page range: 151 - 156
Submitted on: Feb 20, 2025
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Accepted on: May 12, 2025
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Published on: Aug 6, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Huiqing Lv, Xin Ge, Shuping Yang, Fusheng Xu, Hong Liu, Hua Zhang, published by Romanian Association of Laboratory Medicine
This work is licensed under the Creative Commons Attribution 4.0 License.