Have a personal or library account? Click to login
Predictive value of expression of the CXCR4/Akt signaling pathway in the peripheral blood for brain glioma Cover

Predictive value of expression of the CXCR4/Akt signaling pathway in the peripheral blood for brain glioma

By: Xueli Zou  
Open Access
|Jan 2024

References

  1. Amirian ES, Armstrong GN, Zhou R, Lau CC, Claus EB, Barnholtz-Sloan JS, et al. The glioma international case-control study: A report from the Genetic Epidemiology of Glioma International Consortium. Am J Epidemiol. 2016;183(2):85-91. DOI: 10.1093/aje/kwv235
  2. Zhang G, Feng W, Wu J. Down-regulation of SEPT9 inhibits glioma progression through suppressing TGF-β-induced epithelial-mesenchymal transition (EMT). Biomed Pharmacother. 2020;125:109768. DOI: 10.1016/j.biopha.2019.109768
  3. Tu Z, Xie S, Xiong M, Liu Y, Yang X, Tembo KM, et al. CXCR4 is involved in CD133-induced EMT in non-small cell lung cancer. Int J Oncol. 2017;50(2):505-14. DOI: 10.3892/ijo.2016.3812
  4. Yang Q, Wu H, Wang H, Li Y, Zhang L, Zhu L, et al. N-terminal polypeptide derived from vMIP-II exerts its antitumor activity by inhibiting the CXCR4 pathway in human glioma. Int J Oncol. 2017;50(4):1160-74. DOI: 10.3892/ijo.2017.3906
  5. Guo J, Yu X, Gu J, Lin Z, Zhao G, Xu F, et al. Regulation of CXCR4/AKT-signaling-induced cell invasion and tumor metastasis by RhoA, Rac-1, and Cdc42 in human esophageal cancer. Tumour Biol. 2016;37(5):6371-8. DOI: 10.1007/s13277-015-4504-x
  6. Peyvandi AA, Abbaszadeh HA, Roozbahany NA, Pourbakht A, Khoshsirat S, Niri HH, et al. Deferoxamine promotes mesenchymal stem cell homing in noise-induced injured cochlea through PI3K/AKT pathway. Cell Prolif. 2018;51:e12434. DOI: 10.1111/cpr.12434
  7. Hu B, Sun M, Liu J, Hong G, Lin Q. The preventative effect of Akt knockout on liver cancer through modulating NF-κB-regulated inflammation and Bad-related apoptosis signaling pathway. Int J Oncol. 2016;48(4):1467-76. DOI: 10.3892/ijo.2016.3383
  8. Dongre A, Weinberg RA. New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer. Nat Rev Mol Cell Biol. 2019;20(2):69-84. DOI: 10.1038/s41580-018-0080-4
  9. Mittal V. Epithelial Mesenchymal Transition in Tumor Metastasis. Annu Rev Pathol. 2018;13:395-412. DOI: 10.1146/annurevpathol-020117-043854
  10. Nan Y, Guo L, Lu Y, Guo G, Hong R, Zhao L, et al. miR-451 suppresses EMT and metastasis in glioma cells. Cell Cycle. 2021;20(13):1270-8. DOI: 10.1080/15384101.2021.1933303
  11. Xie Q, Huang Z, Yan Y, Li F, Zhong X. [miR-221 mediates epithelialmesenchymal transition-related gene expressions via regulation of PTEN/Akt signaling in drug-resistant glioma cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2014;34(2):218-22.
  12. Wu A, Maxwell R, Xia Y, Cardarelli P, Oyasu M, Belcaid Z, et al. Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment. J Neurooncol. 2019;143(2):241-9. DOI: 10.1007/s11060-019-03172-5
  13. Yi L, Zhou X, Li T, Liu P, Hai L, Tong L, et al. Notch1 signaling pathway promotes invasion, self-renewal and growth of glioma initiating cells via modulating chemokine system CXCL12/CXCR4. J Exp Clin Cancer Res. 2019;38(1):339. DOI: 10.1186/s13046-019-1319-4
  14. Wu Y, Hu Y, Tang L, Yin S, Lv L, Zhou P. Targeting CXCR4 to suppress glioma-initiating cells and chemoresistance in glioma. Cell Biol Int. 2022;46(9):1519-29. DOI: 10.1002/cbin.11836
  15. Li J, Lian ZG, Xu YH, Liu RY, Wei ZQ, Li T, et al. Downregulation of nuclear protein-1 induces cell cycle arrest in G0/G1 phase in glioma cells in vivo and in vitro via P27. Neoplasma. 2020;67(4):843-50. DOI: 10.4149/neo_2020_190814N759
  16. Yang P, Wang G, Huo H, Li Q, Zhao Y, Liu Y. SDF-1/CXCR4 signaling up-regulates survivin to regulate human sacral chondrosarcoma cell cycle and epithelial-mesenchymal transition via ERK and PI3K/AKT pathway. Med Oncol. 2015;32(1):377. DOI: 10.1007/s12032-014-0377-x
  17. Zhao Q, Long Y, Cheng W, Huang Y, Li J, Li Y, et al. Visfatin inhibits colon cancer cell apoptosis and decreases chemosensitivity to 5 FU by promoting the SDF 1/CXCR4/Akt axis. Int J Oncol. 2022;60(6):75. DOI: 10.3892/ijo.2022.5365
  18. Niknami Z, Muhammadnejad A, Ebrahimi A, Harsani Z, Shirkoohi R. Significance of E-cadherin and Vimentin as epithelial-mesenchymal transition markers in colorectal carcinoma prognosis. EXCLI J. 2020;19:917-26. DOI: 10.17179/excli2020-1946
  19. Noronha C, Ribeiro AS, Taipa R, Castro DS, Reis J, Faria C, et al. Cadherin expression and EMT: A focus on gliomas. Biomedicines. 2021;9(10):1328. DOI: 10.3390/biomedicines9101328
  20. Almozyan S, Colak D, Mansour F, Alaiya A, Al-Harazi O, Qattan A, et al. PD-L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation. Int J Cancer. 2017;141(7):1402-12. DOI: 10.1002/ijc.30834
DOI: https://doi.org/10.2478/rrlm-2024-0008 | Journal eISSN: 2284-5623 | Journal ISSN: 1841-6624
Language: English
Page range: 57 - 64
Submitted on: Dec 13, 2023
Accepted on: Jan 16, 2024
Published on: Jan 29, 2024
Published by: Romanian Association of Laboratory Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2024 Xueli Zou, published by Romanian Association of Laboratory Medicine
This work is licensed under the Creative Commons Attribution 4.0 License.