References
- 1. Fruh SM. Obesity: Risk factors, complications, and strategies for sustainable long-term weight management. J Am Assoc Nurse Pract. 2017 Oct; 29(S1): S3-S14. DOI: 10.1002/2327-6924.1251010.1002/2327-6924.12510608822629024553
- 2. Romacho T, Elsen M, Röhrborn D, Eckel J. Adipose tissue and its role in organ crosstalk. Acta Physiol (Oxf). 2014 Apr; 210(4): 733-53. DOI: 10.1111/apha.1224610.1111/apha.1224624495317
- 3. Funcke JB, Scherer PE. Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication. J Lipid Res. 2019 Oct; 60(10): 1648-84. DOI: 10.1194/jlr.R09406010.1194/jlr.R094060679508631209153
- 4. Ramos-Lobo AM, Donato J Jr. The role of leptin in health and disease. Temperature (Austin). 2017 May; 4(3): 258-91. DOI: 10.1080/23328940.2017.132700310.1080/23328940.2017.1327003560516228944270
- 5. Cernea S, Roiban AL, Both E, Huţanu A. Serum leptin and leptin resistance correlations with NAFLD in patients with type 2 diabetes. Diabetes Metab Res Rev. 2018 Nov; 34(8): e3050. DOI: 10.1002/dmrr.305010.1002/dmrr.305030052309
- 6. Cernea S, Both E, Huţanu A, Şular FL, Roiban AL. Correlations of serum leptin and leptin resistance with depression and anxiety in patients with type 2 diabetes. Psychiatry Clin Neurosci. 2019 Dec; 73(12):745-53. DOI: 10.1111/pcn.1292210.1111/pcn.1292231404477
- 7. Marroquí L, Gonzalez A, Ñeco P, Caballero-Garrido E, Vieira E, Ripoll C, et al. Role of leptin in the pancreatic β-cell: effects and signaling pathways. J Mol Endocrinol. 2012 May; 49(1): R9-17. DOI: 10.1530/JME-12-002510.1530/JME-12-002522448029
- 8. Kieffer TJ, Habener JF. The adipoinsular axis: effects of leptin on pancreatic beta-cells. Am J Physiol Endocrinol Metab. 2000 Jan; 278(1): E1-E14. DOI: 10.1152/ajpendo.2000.278.1.E110.1152/ajpendo.2000.278.1.E110644531
- 9. Sáinz N, Barrenetxe J, Moreno-Aliaga MJ, Martínez JA. Leptin resistance and diet-induced obesity: central and peripheral actions of leptin. Metabolism. 2015 Jan; 64(1): 35-46. DOI: 10.1016/j.metabol.2014.10.01510.1016/j.metabol.2014.10.01525497342
- 10. Ibrahim MM. Subcutaneous and visceral adipose tissue: structural and functional differences. Obes Rev. 2010 Jan; 11(1): 11-8. DOI: 10.1111/j.1467-789X.2009.00623.x10.1111/j.1467-789X.2009.00623.x19656312
- 11. HOMA software downloaded from site https://www.dtu.ox.ac.uk/homacalculator/download.php.
- 12. Herrick JE, Panza GS, Gollie JM. Leptin, Leptin Soluble Receptor, and the Free Leptin Index following a Diet and Physical Activity Lifestyle Intervention in Obese Males and Females. J Obes. 2016; 2016: 8375828. DOI: 10.1155/2016/837582810.1155/2016/8375828516855028050279
- 13. Durnin J, Womersley J. Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 1974 Jul; 32(1): 77-97. DOI: 10.1079/BJN1974006010.1079/BJN197400604843734
- 14. Siri WE. Body composition from fluid spaces and density: analysis of methods. 1961. Nutrition. 1993; 9(5): 480-91.
- 15. Harris JA, Benedict FG. A Biometric study of human basal metabolism. Proc Natl Acad Sci U S A. 1918 Dec; 4(12): 370-3. DOI: 10.1073/pnas.4.12.37010.1073/pnas.4.12.370109149816576330
- 16. Bergman RN, Stefanovski D, Buchanan TA, Sumner AE, Reynolds JC, Sebring NG, et al. A better index of body adiposity. Obesity (Silver Spring). 2011 May; 19(5): 1083-9. DOI: 10.1038/oby.2011.3810.1038/oby.2011.38327563321372804
- 17. Amato MC, Giordano C, Galia M, Criscimanna A, Vitabile S, Midiri M, et al. Visceral Adiposity Index: a reliable indicator of visceral fat function associated with cardiometabolic risk. Diabetes Care. 2010 Apr; 33(4): 920-2. DOI: 10.2337/dc09-182510.2337/dc09-1825284505220067971
- 18. Amato MC, Giordano C. Visceral adiposity index: an indicator of adipose tissue dysfunction. Int J Endocrinol. 2014; 2014: 730827. DOI: 10.1155/2014/73082710.1155/2014/730827400933524829577
- 19. Cohen J., Cohen P. Applied multiple regression/correlation analysis for the behavioral sciences. Hillsdale, NJ: Erlbaum. 1983.
- 20. Preacher, K. J. Calculation for the test of the difference between two independent correlation coefficients. 2002; [Computer software]. Available from http://quantpsy.org.
- 21. Chen GC, Qin LQ, Ye JK. Leptin levels and risk of type 2 diabetes: Gender-specific meta-analysis. Obes Rev 2014 Feb; 15(2): 134-42. DOI: 10.1111/obr.1208810.1111/obr.1208824102863
- 22. Wajchenberg BL: Subcutaneous and visceral adipose tissue: Their relation to the metabolic syndrome. Endocr Rev 2000 Dec; 21(6): 697-738. DOI: 10.1210/edrv.21.6.041510.1210/edrv.21.6.041511133069
- 23. Van Harmelen V, Reynisdottir S, Eriksson P, Thörne A, Hoffstedt J, Lönnqvist F, et al. Leptin secretion from subcutaneous and visceral adipose tissue in women. Diabetes. 1998 Jun; 47(6): 913-7. DOI: 10.2337/diabetes.47.6.91310.2337/diabetes.47.6.9139604868
- 24. Marchi M, Lisi S, Curcio M, Barbuti S, Piaggi P, Ceccarini G, et al. Human leptin tissue distribution, but not weight loss-dependent change in expression, is associated with methylation of its promoter. Epigenetics. 2011 Oct; 6(10): 1198-206. DOI: 10.4161/epi.6.10.1660010.4161/epi.6.10.16600322584121931275
- 25. Jablonowska-Lietz B, Wrzosek M, Wlodarczyk M, Nowicka G. New indexes of body fat distribution, visceral adiposity index, body adiposity index, waist-to-height ratio, and metabolic disturbances in the obese. Kardiol Pol 2017; 75(11): 1185-91. DOI: 10.5603/KP.a2017.014910.5603/KP.a2017.014928715064
- 26. Amato MC, Pizzolanti G, Torregrossa V, Misiano G, Milano S, Giordano C. Visceral adiposity index (VAI) is predictive of an altered adipokine profile in patients with type 2 diabetes. PLoS One. 2014; 9(3): e91969. DOI: 10.1371/journal.pone.009196910.1371/journal.pone.0091969396128124651545
- 27. Al-Daghri NM, Al-Attas OS, Alokail M, Alkharfy K, Wani K, Amer OE, et al. Does visceral adiposity index signify early metabolic risk in children and adolescents?: association with insulin resistance, adipokines, and subclinical inflammation. Pediatr Res. 2014; 75(3): 459-63. DOI: 10.1038/pr.2013.22910.1038/pr.2013.22924296798
- 28. Tinggaard J, Hagen CP, Christensen AN, Mouritsen A, Mieritz MG, Wohlfahrt-Veje C, et al. Anthropometry, DXA, and leptin reflect subcutaneous but not visceral abdominal adipose tissue on MRI in 197 healthy adolescents. Pediatr Res. 2017 Oct; 82(4): 620-28. DOI: 10.1038/pr.2017.13810.1038/pr.2017.13828604756
- 29. Fu S, Ying L, Ping P, Luo L,Ye P. Overall obesity had similar ability to identify the insulin resistance and pancreatic β-cell function compared with abdominal obesity in chinese community-dwelling population without type 2 diabetes. Int J Clin Exp Med. 2017; 10(3): 5293-9.
- 30. Fernandes TAP, Gonçalves LML, Brito JAA. Relationships between Bone Turnover and Energy Metabolism. J Diabetes Res. 2017; 2017: 9021314. DOI: 10.1155/2017/902131410.1155/2017/9021314548550828695134
- 31. Rutti S, Dusaulcy R, Hansen JS, Howald C, Dermitzakis ET, Pedersen BK, et al. Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflamma-tory cytokines. Sci Rep. 2018 Jul; 8(1): 10072. DOI: 10.1038/s41598-018-28117-210.1038/s41598-018-28117-2603012329968746
- 32. Hussain MA, Akalestou E, Song WJ. Inter-organ communication and regulation of beta cell function. Diabetologia. 2016 Apr; 59(4): 659-67. DOI: 10.1007/s00125-015-3862-710.1007/s00125-015-3862-7480110426791990
- 33. Seufert J. Leptin effects on pancreatic beta-cell gene expression and function. Diabetes. 2004; 53 Suppl 1: S152-8. DOI: 10.2337/diabetes.53.2007.S15210.2337/diabetes.53.2007.S152
- 34. Morioka T, Emoto M, Yamazaki Y, Kurajoh M, Motoyama K, Mori K et al. Plasma soluble leptin receptor levels are associated with pancreatic β-cell dysfunction in patients with type 2 diabetes. J Diabetes Investig. 2018 Jan; 9(1): 55-62. DOI: 10.1111/jdi.1265710.1111/jdi.12657575452128294581
- 35. Ge H, Huang L, Pourbahrami T, Li C. Generation of soluble leptin receptor by ectodomain shedding of membrane-spanning receptors in vitro and in vivo. J Biol Chem. 2002 Nov; 277(48): 45898-903. DOI: 10.1074/jbc.M20582520010.1074/jbc.M20582520012270921
- 36. Lammert A, Kiess W, Bottner A, Glasow A, Kratzsch J. Soluble leptin receptor represents the main leptin binding activity in human blood. Biochem Biophys Res Commun. 2001 May; 283(4): 982-8. DOI: 10.1006/bbrc.2001.488510.1006/bbrc.2001.488511350082