References
- 1. Cinteza EE, Cinteza M. Biomarkers in Obesity. Rev Romana Med Lab. 2018;26(3):353-8. DOI: 10.2478/rrlm-2018-0027
- 2. Duicu C, Mărginean CO, Voidăzan S, Tripon F, Bănescu C. FTO rs 9939609 SNP Is Associated With Adiponectin and Leptin Levels and the Risk of Obesity in a Cohort of Romanian Children Population. Medicine (Baltimore). 2016 May;95(20):e3709. DOI: 10.1097/MD.0000000000003709
- 3. WHO | Commission on Ending Childhood Obesity. WHO [cited 2019 August 28];Available from: http://www.who.int/end-childhood-obesity/en/
- 4. Cole TJ, Lobstein T. Extended international (IOTF) body mass index cut-offs for thinness, overweight and obesity. Pediatr Obes 2012;7:284-94 DOI: 10.1111/j.2047-6310.2012.00064.x
- 5. Pascanu I, Pop R, Barbu CG, Dumitrescu CP, Gherlan I, Marginean O, et al. development of synthetic growth charts for romanian population. Acta Endocrinol (Bu-char). 2016 Jul-Sep;12(3):309-18. DOI: 10.4183/aeb.2016.309
- 6. Popa S, Moţa M, Popa A, Moţa E, Serafinceanu C, Guja C, et al. Prevalence of overweight/obesity, abdominal obesity and metabolic syndrome and atypical cardiometabolic phenotypes in the adult Romanian population: PREDATORR study. J Endocrinol Invest 2016;39(9): 1045-53. DOI: 10.1007/s40618-016-0470-4
- 7. Chirita-Emandi A, Barbu CG, Cinteza EE, Chesaru BI, Gafencu M, Mocanu V, et al. Overweight and Under-weight Prevalence Trends in Children from Romania- Pooled Analysis of Cross-Sectional Studies between 2006 and 2015. Obes Facts. 2016;9(3):206-20. DOI: 10.1159/000444173
- 8. Mechanick JI, Hurley DL, Garvey WT. Adiposity-based chronic disease as a new diagnostic term: The American Association of Clinical Endocrinologists and American College of Endocrinology Position statement. Endocr Pract. 2017 Mar;23(3):372-78. DOI: 10.4158/EP161688.PS
- 9. Leal Vde O, Mafra D. Adipokines in obesity. Clin Chim Acta. 2013 Apr;419:87-94. DOI: 10.1016/j. cca.2013.02.003
- 10. Bahíllo-Curieses MP, Hermoso-López F, Martínez-Sopena MJ, Cobreros-García P, García-Saseta P, Tríguez-García M, et al. Prevalence of insulin resistance and impaired glucose tolerance in a sample of obese Spanish children and adolescents. Endocrine. 2012 Apr;41(2):289-95. DOI: 10.1007/s12020-011-9540-8
- 11. Damiani D, Kuba VM, Cominato L, Damiani D, Dichtchekenian V, Menezes HC. Metabolic syndrome in children and adolescents: doubts about terminology but not about cardiometabolic risks. Arq Bras Endocrinol Metabol. 2011 Nov;55(8):576-82. DOI: 10.1590/S0004-27302011000800011
- 12. Stastny J, Bienertova-Vasku J, Vasku A. Visfatin and its role in obesity development. Diabetes Metab Syndr. 2012 Apr-Jun;6(2):120-4. DOI: 10.1016/j. dsx.2012.08.011
- 13. Garten A, Petzold S, Barnikol-Oettler A, Körner A, Thasler WE, Kratzsch J, et al. Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes. Biochem Biophys Res Commun. 2010 Jan;391(1):376-81. DOI: 10.1016/j.bbrc.2009.11.066
- 14. Costford SR, Bajpeyi S, Pasarica M, Albarado DC, Thomas SC, Xie H, et al. Skeletal muscle NAMPT is induced by exercise in humans. Am J Physiol Endocrinol Metab. 2010 Jan;298(1):E117-26. DOI: 10.1152/ajpendo.00318.2009
- 15. Martínez Larrad MT, Corbatón Anchuelo A, Fernández Pérez C, Pérez Barba M, Lazcano Redondo Y, Serra-no Ríos M, et al. Obesity and Cardiovascular Risk: Variations in Visfatin Gene Can Modify the Obesity Associated Cardiovascular Risk. Results from the Segovia Population Based-Study. Spain. PloS One. 2016 May;11(5):e0153976. DOI: 10.1371/journal. pone.0153976
- 16. Alkhzouz C, Miclea D, Farcas M, Bucerzan S, Cabau G, Popp RA. Is there a correlation between GAD2 gene -243 A>G polymorphism and obesity? Rev Romana Med Lab. 2019;27(4):413-20. DOI: 10.2478/rrlm-2019-0033
- 17. Pigeyre M, Yazdi FT, Kaur Y, Meyre D. Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity. Clin Science. 2016 Jun;130(12):943-86. DOI: 10.1042/CS20160136
- 18. World Health Organization. Growth reference 5-19 years. 2007. WHO [cited 2019 August 28]; Available from: http://www.who.int/growthref/who2007_bmi_for_age/en/
- 19. Prader A, Largo RH, Molinari L, Issler C. Physical growth of Swiss children from birth to 20 years of age. First Zurich longitudinal study of growth and development. Helv Paediatr Acta Suppl. 1989 Jun;52:1-125.
- 20. National Health and Nutrition Examination Survey. Anthropometry Procedures Manual. 2017. Available from: https://wwwn.cdc.gov/nchs/data/nhanes/2017-2018/manuals/2017_Anthropometry_Procedures_Manual.pdf
- 21. WHO. Waist circumference and waist-hip ratio. WHO [cited 2019 August 28]; Available from: http://www.who.int/nutrition/publications/obesity/WHO_report_waistcircumference_and_waisthip_ratio/en/
- 22. Martin-Calvo N, Moreno-Galarraga L, Martinez-Gonzalez MA. Association between Body Mass Index, Waist-to-Height Ratio and Adiposity in Children: A Systematic Review and Meta-Analysis. Nutrients. 2016;8(8), pii: E512. DOI: 10.3390/nu8080512
- 23. Tanita Corporation of America Inc. „TANITA - Total Body Composition Analyzer SC-331S - Instruction Manual. 2016.
- 24. Mihai G, Gasparik AI, Pascanu IM, Cevei M, Hutanu A, Pop RM. The influence of Visfatin, RBP-4 and insulin resistance on bone mineral density in women with treated primary osteoporosis. Aging Clin Exp Res. 2019 Jun;31(6):889-95. DOI: 10.1007/s40520-019-01206-6
- 25. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta−cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985 Jul;28(7):412-9. DOI: 10.1007/BF00280883
- 26. Andrade MI, Oliveira JS, Leal VS, Lima NM, Costa EC, Aquino NB, et al. Identification of cutoff points for Homeostatic Model Assessment for Insulin Resistance index in adolescents: systematic review. Rev Paul Pediatr. 2016 Jun;34(2):234-42. DOI: 10.1016/j. rppede.2016.01.004
- 27. Ricco RC, Ricco RG, Almeida CAN, Ramos APP. Comparative study of risk factors among children and adolescents with an anthropometric diagnosis of over-weight or obesity. Rev Paul Pediatr. 2010;28(4):320-5. DOI: 10.1590/S0103-05822010000400006
- 28. Castro AV, Kolka CM, Kim SP, Bergman RN. Obesity, insulin resistance and comorbidities? Mechanisms of association. Arq Bras Endocrinol Metabol. 2014 Aug;58(6):600-9. DOI: 10.1590/0004-2730000003223
- 29. Kostovski M, Simeonovski V, Mironska K, Tasic V, Gucev Z. Metabolic Profiles in Obese Children and Adolescents with Insulin Resistance. Open Access Maced J Med Sci. 2018 Mar;6(3):511-8 DOI: 10.3889/oamjms.2018.097
- 30. Pinhas-Hamiel O, Lerner-Geva L, Copperman NM, Jacobson MS. Lipid and insulin levels in obese children: changes with age and puberty. Obes Silver Spring Md. 2007 Nov;15(11):2825-31. DOI: 10.1038/oby.2007.335
- 31. Romualdo MC, Nóbrega FJ, Escrivão MA. Insulin resistance in obese children and adolescents. J Pediatr (Rio J). 2014 Nov-Dec;90(6):600-7. DOI: 10.1016/j. jped.2014.03.005
- 32. Serrano HM, Carvalho GQ, Pereira PF, Peluzio Mdo C, Franceschini Sdo C, Priore SE. Body composition, biochemical and clinical changes of adolescents with excessive adiposity. Arq Bras Cardiol. 2010 Oct;95(4):464-72. DOI: 10.1590/S0066-782X2010005000109
- 33. Chang YH, Chang DM, Lin KC, Shin SJ, Lee YJ. Visfatin in overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome and cardiovascular diseases: a meta-analysis and systemic review. Diabetes Metab Res Rev. 2011 Sept;27(6):515-27. DOI: 10.1002/dmrr.1201
- 34. Kolsgaard ML, Wangensteen T, Brunborg C, Joner G, Holven KB, Halvorsen B, et al. Elevated visfatin levels in overweight and obese children and adolescents with metabolic syndrome. Scand J Clin Lab Invest. 2009;69:858-64. DOI: 10.3109/00365510903348677
- 35. Salama HM, Galal A, Motawie AA, Kamel AF, Ibrahim DM, Aly AA, et al. Adipokines Vaspin and Visfatin in Obese Children. Open Access Maced J Med Sci. 2015 Dec;3(4):563-6. DOI: 10.3889/oamjms.2015.123
- 36. Jian WX, Luo TH, Gu YY, Zhang HL, Zheng S, Dai M, et al. The visfatin gene is associated with glucose and lipid metabolism in a Chinese population. Diabet Med J Br Diabet Assoc. 2006 Sept;23(9):967-73. DOI: 10.1111/j.1464-5491.2006.01909.x
- 37. Li RZ, Ma Xn, Hu XF, Kang SX, Chen SK, Cianflone K, et al. Elevated visfatin levels in obese children are related to proinflammatory factors. J Pediatr Endocrinol Metab. 2013;26(1-2):111-8.
- 38. Filippatos TD, Derdemezis CS, Kiortsis DN, Tselepis AD, Elisaf MS. Increased plasma levels of visfatin/ pre-B cell colony-enhancing factor in obese and over-weight patients with metabolic syndrome. J Endocrinol Invest. 2007 Apr;30(4):323-6. DOI: 10.1007/BF03346300
- 39. Ooi SQ, Chan RM, Poh LK, Loke KY, Heng CK, Chan YH, et al. Visfatin and its genetic variants are associated with obesity-related morbidities and cardiometabolic risk in severely obese children. Pediatr Obes. 2014 Apr;9(2):81-91. DOI: 10.1111/j.2047-6310.2013.00149.x
- 40. Stastny J, Bienertova-Vasku J, Tomandl J, Tomandlova M, Zlamal F, Forejt M, et al. Association of genetic variability in selected regions in visfatin (NAMPT) gene with anthropometric parameters and dietary composition in obese and non-obese Central-European population. Diabetes Metab Syndr. 2013 Jul-Sep;7(3):166-71. DOI: 10.1016/j.dsx.2013.06.001
- 41. Lai A, Chen W, Helm K. Effects of visfatin gene polymorphism RS4730153 on exercise-induced weight loss of obese children and adolescents of Han Chinese. Int J Biol Sci. 2013;9(1):16-21 DOI: 10.7150/ijbs.4918
- 42. Körner A, Böttcher Y, Enigk B, Kiess W, Stumvoll M, Kovacs P. Effects of genetic variation in the visfatin gene (PBEF1) on obesity, glucose metabolism, and blood pressure in children. Metabolism. 2007 Jun;56(6):772-7. DOI: 10.1016/j.metabol.2007.01.009
- 43. Ferrari G, Lima Rodrigues J, Fernandes I, Bueno Jr C. Association between rs4730153 Gene SNP and fasting glucose, triglyceride, HDL and body mass index levels in overweight brazilian adults. Int J Cardiovasc Sci. 2016;29(6):471-76. DOI: 10.5935/2359-4802.20160067
- 44. Duicu C. Genetic testing in pediatrics - a narrative essay of challenges and possibilities in Romania. Rev Romana Med Lab. 2019;27(4):355-9. DOI: 10.2478/rrlm-2019-0041