References
- 1. Choquette AC, Lemieux S, Tremblay A, Drapeau V, Bouchard C, Vohl M-C, et al. GAD2 gene sequence variations are associated with eating behaviors and weight gain in women from the Quebec family study. Physiol Behav. 2009 Oct;98(4):505-10. DOI: 10.1016/j.physbeh.2009.08.004
- 2. Karlsen AE, Hagopian WA, Grubin CE, Dube S, Disteche CM, Adler DA, et al. Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10. Proc Natl Acad Sci U S A. 1991 Oct;88(19):8337-41. DOI: 10.1073/pnas.88.19.8337
- 3. Grone BP, Maruska KP. Three Distinct Glutamate Decarboxylase Genes in Vertebrates. Sci Rep. 2016 Sept;6(1):30507. DOI: 10.1038/srep3050710.1038/srep30507
- 4. Popp A, Urbach A, Witte OW, Frahm C. Adult and Embryonic GAD Transcripts Are Spatiotemporally Regulated during Postnatal Development in the Rat Brain. PLoS One. 2009 Feb;4(2):e4371. DOI: 10.1371/journal.pone.000437110.1371/journal.pone.0004371
- 5. Trifonov S, Yamashita Y, Kase M, Maruyama M, Sugimoto T. Glutamic acid decarboxylase 1 alternative splicing isoforms: characterization, expression and quantification in the mouse brain. BMC Neurosci. 2014 Oct;15(1):114. DOI: 10.1186/1471-2202-15-11410.1186/1471-2202-15-114
- 6. Cram DS, Barnett LD, Joseph JL, Harrison LC. Cloning and partial nucleotide sequence of human glutamic acid decarboxylase cDNA from brain and pancreatic islets. Biochem Biophys Res Commun. 1991 May;176(3):1239-44. DOI: 10.1016/0006-291X(91)90418-710.1016/0006-291X(91)90418-7
- 7. Davis KN, Tao R, Li C, Gao Y, Gondré-Lewis MC, Lips-ka BK, et al. GAD2 Alternative Transcripts in the Human Prefrontal Cortex, and in Schizophrenia and Affective Disorders. PLoS One. 2016 Feb;11(2):e0148558. DOI: 10.1371/journal.pone.0148558
- 8. Albert LJ, Inman RD. Molecular Mimicry and Auto-immunity. N Engl J Med. 1999 Dec;341(27):2068-74. DOI: 10.1056/NEJM199912303412707
- 9. Tuomi T, Carlsson A, Li H, Isomaa B, Miettinen A, Nilsson A, et al. Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies. Diabetes. 1999 Jan;48(1):150-7. DOI: 10.2337/diabetes.48.1.15010.2337/diabetes.48.1.150
- 10. Fink AJP, Croce KR, Huang ZJ, Abbott LF, Jessell TM, Azim E. Presynaptic inhibition of spinal sensory feedback ensures smooth movement. Nature. 2014 May;509(7498):43-8. DOI: 10.1038/nature13276
- 11. Boloc D, Mas S, Rodriguez N, Ortiz AE, Morer A, Plana MT, et al. Genetic Associations of Serotoninergic and GABAergic Genes in an Extended Collection of Early-Onset Obsessive-Compulsive Disorder Trios. J Child Adolesc Psychopharmacol. 2019 Mar;29(2):152-7. DOI: 10.1089/cap.2018.007310.1089/cap.2018.0073
- 12. Lizarbe B, Soares AF, Larsson S, Duarte JMN. Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet. Front Neurosci. 2019 Jan;12:985. DOI: 10.3389/fnins.2018.0098510.3389/fnins.2018.00985
- 13. Jarvie BC, King CM, Hughes AR, Dicken MS, Dennison CS, Hentges ST. Caloric restriction selectively reduces the GABAergic phenotype of mouse hypothalamic proopiomelanocortin neurons. J Physiol. 2017 Jan;595(2):571-82. DOI: 10.1113/JP27302010.1113/JP273020
- 14. Wang Q, Ren L, Wan Y, Prud’homme GJ. GABAergic regulation of pancreatic islet cells: Physiology and anti-diabetic effects. J Cell Physiol. 2019 Jan;12:985.
- 15. Boutin P, Froguel P. GAD2: a polygenic contribution to genetic susceptibility for common obesity? Pathol Biol (Paris). 2005 Jul;53(6):305-7. DOI: 10.1016/j.patbio.2004.09.00810.1016/j.patbio.2004.09.008
- 16. Boutin P, Dina C, Vasseur F, Dubois S, Corset L, Séron K, et al. GAD2 on Chromosome 10p12 Is a Candidate Gene for Human Obesity. John Bell, editor. PLoS Biol. 2003 Nov;1(3):e68. DOI: 10.1371/journal.pbio.000006810.1371/journal.pbio.0000068
- 17. Meyre D, Boutin P, Tounian A, Deweirder M, Aout M, Jouret B, et al. Is Glutamate Decarboxylase 2 (GAD2) a Genetic Link between Low Birth Weight and Subsequent Development of Obesity in Children? J Clin Endocrinol Metab. 2005 Apr;90(4):2384-90. DOI: 10.1210/jc.2004-146810.1210/jc.2004-1468
- 18. Prakash J, Mittal B, Awasthi S, Srivastava N. Association of the -243A>G, +61450C>A Polymorphisms of the Glutamate Decarboxylase 2 (GAD2) Gene with Obesity and Insulin Level in North Indian Population. Iran J Public Health. 2016 Apr;45(4):460-8.
- 19. Swarbrick MM, Waldenmaier B, Pennacchio LA, Lind DL, Cavazos MM, Geller F, et al. Lack of support for the association between GAD2 polymorphisms and severe human obesity. PLoS Biol. 2005 Sep;3(9):e315. DOI: 10.1371/journal.pbio.003031510.1371/journal.pbio.0030315
- 20. Obesity and overweight. 22 iulie 2019 [citat 22 iulie 2019]; Available at: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
- 21. Hager J, Dina C, Francke S, Dubois S, Houari M, Vatin V, et al. A genome-wide scan for human obesity genes reveals a major susceptibilitylocus on chromosome 10. Nat Genet. 1998 Nov;20(3):304-8. DOI: 10.1038/3123
- 22. Cinteza EE, Cinteza M. Biomarkers in Obesity. Rev Romana Med Lab. 2018;26(3):353-8. DOI: 10.2478/rrlm-2018-0027
- 23. Kosse C, Schöne C, Bracey E, Burdakov D. Orexin-driven GAD65 network of the lateral hypothalamus sets physical activity in mice. Proc Natl Acad Sci. 2017 Apr;114(17):4525-30. DOI: 10.1073/pnas.161970011410.1073/pnas.1619700114
- 24. Duicu C, Mărginean CO, Voidăzan S, Tripon F, Bănes-cu C. FTO rs 9939609 SNP Is Associated With Adiponectin and Leptin Levels and the Risk of Obesity in a Cohort of Romanian Children Population. Medicine (Baltimore). 2016 May;95(20):e3709. DOI: 10.1097/MD.000000000000370910.1097/MD.0000000000003709
- 25. Tilinca MC, Barabas-Hajdu EC, Tusa Ferencz G, Nemes-Nagy E. Involvement of inflammatory cytokines in obesity and its complications. Rev Romana Med Lab. 2018;26(3):359-71. DOI: 10.2478/rrlm-2018-001910.2478/rrlm-2018-0019