Genotype comparison of Candida albicans isolates from different clinical samples

Bostănaru, Andra-Cristina; Roșca, Irina; Minea, Bogdan; Năstasă, Valentin; Foia, Liliana; Marincu, Iosif; Mares, Mihai; Mederle, Ovidiu-Alexandru

doi:10.2478/rrlm-2019-0027

Abstract

Background: Fungal infections are a health issue paradoxically fuelled by the developments in medical care. Objectives: Our study is an investigation on the correlation between the infection site and the genotypes of Candida albicans strains isolated from Romanian patients. Methods: A total number of 301 isolates from different clinical sites were investigated in terms of genotype determination. Results: The isolates were clustered in three groups according to their genotype: 55.81% showed genotype A, 14.62% genotype B, and 29.57% genotype C. Conclusions: No significant correlation was found between the genotype and the infection site, but a significant correlation was found between genotype C and isolates from HIV patients proving that C. albicans pathogenicity probably relies on factors related to the host.

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Genotype comparison of Candida albicans isolates from different clinical samples

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