Multiplex ligation dependent probe amplification - A useful, fast and cost-effective method for identification of small supernumerary marker chromosome in children with developmental delay and congenital heart defect

Abbreviations

CHD -

congenital heart disease

CNVs -

copy number variants

AVC -

atrioventricular canal

PDA -

persistent ductus arteriosus

VSD –

ventricular septal defects

ASD –

atrial septal defects

FISH -

fluorescence in situ hybridization

MLPA -

multiplex ligation-dependent probe amplification

CGH -

comparative genomic hybridization

WGA -

whole-genome array