Have a personal or library account? Click to login
Prognostic value of immunohistochemical expression of ZAP-70 and CD38 in chronic lymphocytic leukaemia detected on bone marrow and lymph node biopsies  / Valoarea prognostică a expresiei imunohistochimice a ZAP-70 si CD38 în leucemia limfocitară cronică detectată pe biopsii osteomedulare și limfoganglionare Cover

Prognostic value of immunohistochemical expression of ZAP-70 and CD38 in chronic lymphocytic leukaemia detected on bone marrow and lymph node biopsies / Valoarea prognostică a expresiei imunohistochimice a ZAP-70 si CD38 în leucemia limfocitară cronică detectată pe biopsii osteomedulare și limfoganglionare

Open Access
|Dec 2014

References

  1. 1. Keating MJ, Chiorazzi N, Messmer B, Damle RN, Allen SL, Rai KR, et al. Biology and Treatment of Chronic Lymphocytic Leukemia. Hematology Am Soc Hematol Educ Program. 2003; 153-75. DOI: 10.1182/ asheducation-2003.1.15310.1182/asheducation-2003.1.15314633781
  2. 2. Shanafelt TD, Geyer SM, Kay NE. Prognosis at diagnosis: integrating molecular biologic insights into clinical practice for patients with CLL. Blood. 2004 Feb 15; 103(4):1202-10. DOI: 10.1182/blood-2003-07-228110.1182/blood-2003-07-228114576043
  3. 3. Siddon AJ, Rinder HM. Pathology consulatation on evaluating prognosis in incidental monoclonal lymphocytosis and chronic lymphocytic leukemia. Am J Clin Pathol. 2013 Jun; 139(6):708-12. DOI: 10.1309/ AJCPLIR4GZWX3XKA10.1309/AJCPLIR4GZWX3XKA23690112
  4. 4. Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leuke mia. Blood. 1999 Sep 15; 94(6):1848-54.10.1182/blood.V94.6.1848.418k05_1848_1854
  5. 5. Hamblin TJ. Searching for surrogates for IGVH mutations in chronic lymphocytic leukemia. Leuk Res. 2011 Nov;35(11):1432-5. DOI: 10.1016/j.leukres. 2011.07.020
  6. 6. Crespo M, Bosch F, Villamor N, Bellosillo B, Colomer D, Rozman M, et al. ZAP-70 expression as a surrogate for immunoglobulin variable-region mutations in chronic lymphocytic leukemia. N Engl J Med. 2003 May 1; 348(18):1764-75. DOI: 10.1056/NEJMoa02314310.1056/NEJMoa02314312724482
  7. 7. Wiggers TGH, Westra G, Westers TM, Abbes AP, Strunk A, Kuiper-Kramer E, et al. ZAP70 in B-CLL Cells Related to the Expression in NK Cells is a Surrogate Marker for Mutational Status. Cytometry Part B. 2014 Jul; 86(4):280-7. DOI: 10.1002/cyto.b.2113210.1002/cytob.2113224124110
  8. 8. Weiss A, Iwashima M, Irving B, van Oers NS, Kadlecek TA, Straus D, et al. Molecular and genetic insights into T cell antigen receptor signal transduction. Adv Exp Med Biol. 1994; 365:53-62. DOI: 10.1007/978-1-4899-0987-9_610.1007/978-1-4899-0987-9_67887313
  9. 9. Weiss A, Chan AC, Iwashima M, Straus D, Irving BA. Regulation of protein tyrosine kinase activation by the T-cell antigen receptor zeta chain. Cold Spring Harb Symp Quant Biol. 1992;57:107-16. DOI: 10.1101/ SQB.1992.057.01.01410.1101/SQB.1992.057.01.0141339649
  10. 10. Nolz JC, Tschumper RC, Pittner BT, Darce JR, Kay NE, Jelinek DF. ZAP-70 is expressed by a subset of normal human B-lymphocytes displaying an activated phenotype. Leukemia. 2005 Jun; 19(6):1018-24. DOI: 10.1038/sj.leu.240372610.1038/sj.leu.240372615800671
  11. 11. Scielzo C, Camporeale A, Geuna M, Alessio M, Poggi A, Zocchi A, et al. ZAP-70 is expressed by normal and malignant human B-cell subsets of different maturational stage. Leukemia. 2006 Apr; 20(4):689-95. DOI: 10.1038/sj.leu.240413810.1038/sj.leu.240413816482211
  12. 12. Chen L, Widhopf G, Huynh L, Rassenti L, Rai KR, Weiss A, et al. Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood. 2002 Dec 15; 100(13):4609-14. DOI: 10.1182/blood-2002-06-168310.1182/blood-2002-06-1683
  13. 13. Crespo M, Bosch F, Villamor N, Bellosillo B, Colomer D, Rozman M, et al. ZAP-70 expression as a surrogate for immunoglobulin variable-region mutations in chronic lymphocytic leukemia. N Engl J Med. 2003; 348(18):1764-75. DOI:10.1056/NEJMoa02314310.1056/NEJMoa023143
  14. 14. Orchard JA, Ibbotson RE, Davis Z, Wiestner A, Rosenwald A, Thomas PW, et al. ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet. 2004 Jan 10;363(9403):105-11. DOI: 10.1016/S0140-6736(03)15260-910.1016/S0140-6736(03)15260-9
  15. 15. Rassenti LZ, Huynh L, Toy TL, Chen L, Keating MJ, Gribben JG et al. ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. N Engl J Med. 2004; 351(9):893-01. DOI: 10.1056/NEJMoa04085710.1056/NEJMoa04085715329427
  16. 16. Gobessi S, Laurenti L, Longo PG, Sica S, Leone G, Efremov DG. ZAP-70 enhances B-cell-receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells. Blood. 2007 Mar 1;109(5):2032-9. DOI: 10.1182/ blood-2006-03-01175910.1182/blood-2006-03-01175917038529
  17. 17. Claus R, Lucas DM, Ruppert AS, Williams KE, Weng D, Patterson K, et al. Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocyticleukemia Blood. 2014 Jul 3;124(1):42-8. DOI: 10.1182/blood-2014-02-55572210.1182/blood-2014-02-555722412535324868078
  18. 18. Deaglio S, Capobianco A, Bergui L, et al. CD38 is a signaling molecule in B-cell chronic lymphocytic leukemia cells. Blood. 2003 Sep 15;102(6):2146-55. DOI: 10.1182/blood-2003-03-098910.1182/blood-2003-03-098912763926
  19. 19. Jaksic O, Paro MM, Kardum Skelin I, Kusec R, Pejsa V, Jaksic B. CD38 on B-cell chronic lymphocytic leukemia cells has higher expression in lymph nodes than in peripheral blood or bone marrow. Blood. 2004 Mar 1; 103(5):1968-9. DOI: 10.1182/blood-2003-11-389010.1182/blood-2003-11-389014976064
  20. 20. Adams RLC, Cheung C, Banh R, Saal R, Cross D, Gill D, et al. Prognostic value of ZAP-70 expression in chronic lymphocytic leukemia as assessed by quantitative polymerase chain reaction and flow cytometry. Cytometry B Clin Cytom. 2014 Mar; 86(2):80-90. DOI: 10.1002/cyto.b.2113810.1002/cytob.2113824127306
  21. 21. Shanafelt TD, Geyer SM, Kay NE. Prognosis at diagnosis: integrating molecular biologic insights into clinical practice for patients with CLL. Blood. 2004 Feb 15; 103(4):1202-10. DOI: 10.1182/blood-2003-07-228110.1182/blood-2003-07-228114576043
  22. 22. Durig J, Naschar M, Schmucker U, Renzing-Kohler K, Holter T, Huttmann A et al. Cd38 expression is an important prognostic marker in chronic lymphocytic leukaemia. Leukemia 2002 Jan; 16(1):30-510.1038/sj.leu.240233911840260
  23. 23. Zanotti R, Ambrosetti A, Lestani M, Ghia P, Pattaro C, Remo A, et al. ZAP-70 expression, as detected by immunohistochemistry on bone marrow biopsies from early-phase CLL patients, is a strong adverse prognostic factor. Leukemia. 2007 Jan; 21(1):102-9. DOI: 10.1038/sj.leu.240445810.1038/sj.leu.240445817082778
  24. 24. Carreras J, Villamor N, Colomo L, Moreno C, Ramon y Cajal S, Crespo M, et al. Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasms. J Pathol. 2005 Mar; 205(4):507-13. DOI: 10.1002/path.172710.1002/path.172715685592
  25. 25. Gibbs G, Bromidge T, Howe D, Hopkins J, Johnson S. Comparison of flow cytometric methods for the mea surement of ZAP-70 expression in a routine diagnostic laboratory. Clin Lab Haematol. 2005 Aug;27(4):258-66. DOI: 10.1111/j.1365-2257.2005.00703.x10.1111/j.1365-2257.2005.00703.x16048494
  26. 26. Tsimberidou AM, Keating MJ, Bueso-Ramos CE, Kurzrock R. Epstein-Barr virus in patients with chronic lymphocytic leukemia: a pilot study. Leuk Lymphoma. 2006 May; 47(5):827-36. DOI: 10.1080/1042819050039885610.1080/1042819050039885616753866
  27. 27. Tsimberidou AM, O’Brien S, Kantarjian HM, Koller C, Hagemeister FB, Fayad L, et al. Hodgkin transformation of chronic lymphocytic leukemia: the M. D. Anderson Cancer Center experience. Cancer. 2006 Sep 15; 107(6):1294-302. DOI: 10.1002/cncr.2212110.1002/cncr.2212116902984
  28. 28. Petrella T, Yaziji N, Collin F, Rifle G, Morlevat F, Arnould L, et al. Implication of the Epstein-Barr virus in the progression of chronic lymphocytic leukaemia/ small lymphocytic lymphoma to Hodgkin-like lymphomas. Anticancer Res. 1997 sep-Oct; 17(5B):3907-13.
DOI: https://doi.org/10.2478/rrlm-2014-0041 | Journal eISSN: 2284-5623 | Journal ISSN: 1841-6624
Language: English
Page range: 497 - 505
Submitted on: Aug 13, 2014
|
Accepted on: Nov 4, 2014
|
Published on: Dec 30, 2014
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2014 Bogdan Fetica, Ana-Maria Fit, Luminița Blaga, Annamaria Fulop, Bogdan Pop, Delia Dima, Andrei Cucuianu, Ljubomir Petrov, published by Romanian Association of Laboratory Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.